scholarly journals A rapid, simple, and sensitive immunoagglutination assay with silica nanoparticles for serotype identification of Pseudomonas aeruginosa

2019 ◽  
Vol 18 (8) ◽  
pp. 1936-1943
Author(s):  
Xiu-mei DONG ◽  
Jing TAO ◽  
Ting-ting LI ◽  
Ping ZHANG ◽  
Yan ZHU ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Silica Nanoparticles ◽  
Serotype Identification

Antimicrobial and antibiofilm activities of meropenem loaded-mesoporous silica nanoparticles against carbapenem-resistant Pseudomonas aeruginosa

2021 ◽  
pp. 088532822110038
Author(s):  
Mohammad Yousef Memar ◽  
Mina Yekani ◽  
Hadi Ghanbari ◽  
Edris Nabizadeh ◽  
Sepideh Zununi Vahed ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Carbapenem Resistant ◽  
Toxicity In Vitro ◽  
Different Levels

The aims of the present study were the determination of antimicrobial and antibiofilm effects of meropenem-loaded mesoporous silica nanoparticles (MSNs) on carbapenem resistant Pseudomonas aeruginosa ( P. aeruginosa) and cytotoxicity properties in vitro. The meropenem-loaded MSNs had shown antibacterial and biofilm inhibitory activities on all isolates at different levels lower than MICs and BICs of meropenem. The viability of HC-04 cells treated with serial concentrations as MICs and BICs of meropenem-loaded MSNs was 92–100%. According to the obtained results, meropenem-loaded MSNs display the significant antibacterial and antibiofilm effects against carbapenem resistant and biofilm forming P. aeruginosa and low cell toxicity in vitro. Then, the prepared system can be an appropriate option for the delivery of carbapenem for further evaluation in vivo assays.

scholarly journals Bifunctional silica nanoparticles for the exploration of Pseudomonas aeruginosa biofilm

2016 ◽  
Author(s):  
L. Mauline ◽  
M. Gressier ◽  
P. Hammer ◽  
S. J. L. Ribeiro ◽  
J. M. A. Caiut ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Silica Nanoparticles

scholarly journals Acute exposure to silica nanoparticles enhances mortality and increases lung permeability in a mouse model of Pseudomonas aeruginosa pneumonia

2015 ◽  
Vol 12 (1) ◽  
Author(s):  
Mathilde Delaval ◽  
Sonja Boland ◽  
Brigitte Solhonne ◽  
Marie-Anne Nicola ◽  
Stéphane Mornet ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Mouse Model ◽  
Silica Nanoparticles ◽  
Acute Exposure ◽  
Lung Permeability
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