scholarly journals In vitro antiplasmodial activity of ethanolic extracts of South Indian medicinal plants against Plasmodium falciparum

2012 ◽  
Vol 2 (3) ◽  
pp. 180-183 ◽  
Author(s):  
Sundaram Ravikumar ◽  
Samuel Jacob Inbaneson ◽  
Palavesam Suganthi
Keyword(s):  
Plasmodium Falciparum ◽  
Medicinal Plants ◽  
Antiplasmodial Activity ◽  
South Indian ◽  
Ethanolic Extracts ◽  
Indian Medicinal Plants

In vitro screening of Indian medicinal plants for antiplasmodial activity

2001 ◽  
Vol 74 (2) ◽  
pp. 195-204 ◽  
Author(s):  
Henrik Toft Simonsen ◽  
Jesper Brændegaard Nordskjold ◽  
Ulla Wagner Smitt ◽  
Ulf Nyman ◽  
Pushpangadan Palpu ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Antiplasmodial Activity ◽  
In Vitro Screening ◽  
Indian Medicinal Plants

In vitro antiplasmodial activity of ethanolic extracts of seaweed macroalgae against Plasmodium falciparum

2010 ◽  
Vol 108 (6) ◽  
pp. 1411-1416 ◽  
Author(s):  
Sundaram Ravikumar ◽  
Samuel Jacob Inbaneson ◽  
Palavesam Suganthi ◽  
Ramasamy Gokulakrishnan ◽  
Malaiyandi Venkatesan
Keyword(s):  
Plasmodium Falciparum ◽  
Antiplasmodial Activity ◽  
Ethanolic Extracts

scholarly journals In Vitro Assessment Of The Antiplasmodial Activity Of Three Plants Extracts Used In Local Traditional Medicine In Saloum (Senegal)

2016 ◽  
Vol 12 (12) ◽  
pp. 157 ◽  
Author(s):  
Ousmane Niass ◽  
Serigne Omar Sarr ◽  
Baba Dieye ◽  
Amadou Diop ◽  
Yerim Mbagnick Diop
Keyword(s):  
Plasmodium Falciparum ◽  
Medicinal Plants ◽  
Aerial Part ◽  
Antiplasmodial Activity ◽  
Phytochemical Compounds ◽  
In Vitro Assessment ◽  
Strychnos Spinosa ◽  
Ethyl Acetate Extracts ◽  
Important Activity

Against the scourge of malaria in Africa and the development of chemo-resistance, discovering new natural cures is a major concern for many researchers. As a consequence, the present study was carried out in order, first, to identify the phytochemical compounds, and second, to assess the antiplasmodial activity, of three medicinal plants extracts, selected from an ethno-botany survey conducted in Senegal. The parts of the plants used were Strychnos spinosa (Strychnaceae) leaves and stems, Combretum glutinosum (Combretaceae) barks, and the whole aerial part of Pennisetum polystachion (Poaceae). Among these plants, the hydromethanolic extracts of Strychnos spinosa stems showed the most important activity against Plasmodium falciparum strains, with a IC50 of 15 μg/ml, followed by the leaves chlorophormic extracts and the ethyl acetate extracts of Pennisetum polystachion, with respective IC50 of 20 μg/ml and 21 μg/ml. Combretum glutinosum extracts showed the least important activity, in all tests.

scholarly journals Antiplasmodial activity of Anthocleista djalonensis leaves extracts against clinical isolates of Plasmodium falciparum and multidrug resistant K1 strains

2020 ◽  
Vol 8 (3) ◽  
pp. 130-138
Author(s):  
Brice Kouakou Bla ◽  
Oléfongo Dagnogo ◽  
Rolland Gueyraud Kipré ◽  
Opportune Gogo Ballé ◽  
Jonhson David Trébissou ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Multidrug Resistant ◽  
Traditional Healers ◽  
Antiplasmodial Activity ◽  
Clinical Isolates ◽  
Aqueous Extracts ◽  
Phytochemical Screening ◽  
Primary Health ◽  
Ethanolic Extracts

Information collected from nine (09) traditional healers in the Moronou village in the Department of Toumodi revealed that Anthocleista djanlonensis is regularly used by the population for primary health care in the processing of malaria. Evaluation of the In vitro antiplasmodial activity showed that the aqueous extracts inhibit growth of clinical isolates and chloroquinoresistant strains (K1) with IC50 of 8.29 µg/mL and 10.23 µg/mL while the ethanolic extracts had IC50 of 37.65 µg/mL and 46.07 µg/mL on the same strains respectively. Results of the In vitro antimalarial bioassay showed that aqueous extracts have promising antiplasmodial effects on clinical isolates and on Plasmodium falciparum multidrug resistant K1 strain (3 µg/mL <IC50 <15 µg/mL). Phytochemical screening revealed that the extracts contain mainly alkaloids, polyphenols, polyterpenes and flavonoids

scholarly journals Assessment of Antimalarial Activity againstPlasmodium falciparumand Phytochemical Screening of Some Yemeni Medicinal Plants

2009 ◽  
Vol 6 (4) ◽  
pp. 453-456 ◽  
Author(s):  
Mohammed A. Alshawsh ◽  
Ramzi A. Mothana ◽  
Hassan A. Al-shamahy ◽  
Salah F. Alsllami ◽  
Ulrike Lindequist
Keyword(s):  
Medicinal Plants ◽  
Antimalarial Activity ◽  
Traditional Healers ◽  
Antiplasmodial Activity ◽  
World Health ◽  
Moderate Activity ◽  
Phytochemical Screening ◽  
Cissus Rotundifolia ◽  
Health Organization

Developing countries, where malaria is one of the most prevalent diseases, still rely on traditional medicine as a source for the treatment of this disease. In the present study, six selected plants (Acalypha fruticosa,Azadirachta indica,Cissus rotundifolia,Echium rauwalfii,Dendrosicyos socotranaandBoswellia elongata) commonly used in Yemen by traditional healers for the treatment of malaria as well as other diseases, were collected from different localities of Yemen, dried and extracted with methanol and water successfully. The antiplasmodial activity of the extracts was evaluated against fresh clinical isolates ofPlasmodium falciparum. The selectivity parameters to evaluate the efficacy of these medicinal plants were measured byin vitromicro test (Mark III) according to World Health Organization (WHO) 1996 & WHO 2001 protocols of antimalarial drug tests. Among the investigated 12 extracts, three were found to have significant antiplasmodial activity with IC50values less than 4 µg/ml, namely the water extracts ofA. fruticosa,A. indicaandD. socotrana. Six extracts showed moderate activity with IC50values ranging from 10 to 30 µg/ml and three appeared to be inactive with IC50values more than 30 µg/ml. In addition, preliminary phytochemical screening of the methanolic and aqueous extracts indicated the presence of saponins, tannins, flavonoids, terpenoids, polysaccharides and peptides.

scholarly journals Screening Indian Medicinal Plants to Control Diabetes – An In silico and In vitro Approach

2017 ◽  
Vol 05 (02) ◽  
Author(s):  
Fazeela Mehaboob Begum SM ◽  
Zakia Fathima S ◽  
Priya S ◽  
Sundararajan R ◽  
Hemalatha S
Keyword(s):  
Medicinal Plants ◽  
In Silico ◽  
Indian Medicinal Plants ◽  
Control Diabetes
Sign in / Sign up

Export Citation Format

Share Document