The impact of COVID-19 on bladder cancer patients: Irish experience from a tertiary care teaching hospital

Objective: A sharp increase in chronic diseases for elderly patients has been observed in recent years resulting in polypharmacy, which may lead to drug-drug interactions (DDI’s), drug-related problems, adverse drug reactions (ADR’s), and many more issues in these patients. The present study was conducted to assess the clinical consequences of polypharmacy and its prevalence in the older adult population. Methods: Our work is a prospective, observational study carried out in a tertiary care teaching hospital. The polypharmacy prescriptions were identified (taking at least five medications), and drug-drug interactions were detected by Micromedex® DrugReax® System 2.0 version. The medication profiles were also checked for inappropriate prescribing according to Beers Criteria 2015. Results: In the study, the mean age of patients was found to be 72.4±8.8 years. Most of the patients (81.8%) had more than two and less than five diseases. The mean number of drugs prescribed in all the prescriptions was found to be 7.4±2.6. According to Beers Criteria-2015, 3.83% of the total medications prescribed were inappropriate, 74.1% of moderate DDI’s were observed in patients, and 50.2% of the DDI’s observed theoretically were documented as fair. Conclusion: The impact of polypharmacy on consequences such as the length of stay, DDI’s, and DRP’s was also found to be significant. This study concludes that the medication profile of older adult patients should be assessed regularly for the rationality of drug therapy to maximize the therapeutic response positively with the lowest number of medications possible.

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4CPS-023 Impact of drug and therapeutic committee intervention on rationalisation of albumin use in cancer patients admitted to surgery wards of a tertiary care teaching hospital

10.1136/ejhpharm-2018-eahpconf.114 ◽

2018 ◽

Author(s):

S Ebrahim Poor ◽

M Mohammadi ◽

S Namazi ◽

Z Jahangard-Rafsanjani

Keyword(s):

Cancer Patients ◽

Teaching Hospital ◽

Tertiary Care ◽

Tertiary Care Teaching Hospital ◽

Care Teaching

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A study of drug-drug interactions in cancer patients of a south Indian tertiary care teaching hospital

Journal of Postgraduate Medicine ◽

10.4103/0022-3859.85207 ◽

2011 ◽

Vol 57 (3) ◽

pp. 206 ◽

Cited By ~ 13

Author(s):

G Kannan ◽

VanithaN Rani ◽

J Alosh ◽

JR Martin ◽

R Anitha ◽

...

Keyword(s):

Drug Interactions ◽

Cancer Patients ◽

Teaching Hospital ◽

Tertiary Care ◽

Tertiary Care Teaching Hospital ◽

Care Teaching ◽

South Indian

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Evaluation of trigger tool method for adverse drug reaction reporting by nursing staff at a tertiary care teaching hospital

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20192175 ◽

2019 ◽

Vol 8 (6) ◽

pp. 1139

Author(s):

Urmila J. Menat ◽

Chetna K. Desai ◽

Megha K. Shah ◽

Asha N. Shah

Keyword(s):

Teaching Hospital ◽

Adverse Drug Reaction Reporting ◽

Tertiary Care ◽

Educational Interventions ◽

Drug Event ◽

Trigger Tool ◽

Medicine Department ◽

Tertiary Care Teaching Hospital ◽

Care Teaching ◽

The Impact

Background: To sensitize nurses about Trigger Tool Method (TTM) and to evaluate the impact of TTM on adverse drug event (ADE) reporting by nurses at a tertiary care teaching hospital in India.Methods: This was prospective, interventional, single center study conducted among nursing health professionals of Civil Hospital Ahmedabad (CHA) posted in Medicine Department. They were sensitized about ADE reporting, pharmacovigilance, methods of ADRs reporting and details about TTM. Also, a list of 17 triggers was prepared by the investigator and given to nurses. They were educated to report ADEs using TTM. At the initiation and end of study, questionnaires were given to evaluate knowledge, attitude and practice of ADR reporting among participant nurses. All triggers and ADEs reported were analyzed in terms of association between them, effectiveness of trigger in detecting an ADR and in terms of Positive Predictive Value (PPV). Reported ADRs were also assessed for causality, severity and preventability.Results: A total 758 patients were admitted during the study period in the respective medicine department. List of 17 triggers consists of 9 drug triggers (DT), 1 laboratory trigger (LT) and 7 patient triggers (PT). Of these 17 triggers, 14 triggers were identified by nurses. These 14 triggers were noticed 130 times. These included DT (100 times), LT (0 times) and PT (30 times). Of the various triggers observed, 7 DT and 4 PT were related to ADRs. Hence, 11 triggers (64.70%) were positive (related to ADRs), out of 17 total triggers under evaluation. 21 ADRs were observed using TTM by nurses.Conclusions: The TTM helps to detect and report ADRs by nurses. Educational interventions about TTM help in better detection and reporting of ADRs.

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