scholarly journals Evaluation of trigger tool method for adverse drug reaction reporting by nursing staff at a tertiary care teaching hospital

Author(s):  
Urmila J. Menat ◽  
Chetna K. Desai ◽  
Megha K. Shah ◽  
Asha N. Shah

Background: To sensitize nurses about Trigger Tool Method (TTM) and to evaluate the impact of TTM on adverse drug event (ADE) reporting by nurses at a tertiary care teaching hospital in India.Methods: This was prospective, interventional, single center study conducted among nursing health professionals of Civil Hospital Ahmedabad (CHA) posted in Medicine Department. They were sensitized about ADE reporting, pharmacovigilance, methods of ADRs reporting and details about TTM. Also, a list of 17 triggers was prepared by the investigator and given to nurses. They were educated to report ADEs using TTM. At the initiation and end of study, questionnaires were given to evaluate knowledge, attitude and practice of ADR reporting among participant nurses. All triggers and ADEs reported were analyzed in terms of association between them, effectiveness of trigger in detecting an ADR and in terms of Positive Predictive Value (PPV). Reported ADRs were also assessed for causality, severity and preventability.Results: A total 758 patients were admitted during the study period in the respective medicine department. List of 17 triggers consists of 9 drug triggers (DT), 1 laboratory trigger (LT) and 7 patient triggers (PT). Of these 17 triggers, 14 triggers were identified by nurses. These 14 triggers were noticed 130 times. These included DT (100 times), LT (0 times) and PT (30 times). Of the various triggers observed, 7 DT and 4 PT were related to ADRs. Hence, 11 triggers (64.70%) were positive (related to ADRs), out of 17 total triggers under evaluation. 21 ADRs were observed using TTM by nurses.Conclusions: The TTM helps to detect and report ADRs by nurses. Educational interventions about TTM help in better detection and reporting of ADRs.

Cureus ◽  
2021 ◽  
Author(s):  
Srikanta Padhan ◽  
Pugazhenthan T ◽  
Ramesh Chandrakar ◽  
Abhiruchi Galhotra ◽  
Nitinkumar B Borkar

2020 ◽  
Vol 13 (4) ◽  
pp. 350-355
Author(s):  
M. Sreenivasulu ◽  
K. Sivaiah ◽  
V.Jagadeesh Naik

Background: An interaction is alleged to occur once the consequences of one drug is changed by the presence of another drug, herbal medicine, food, drink or by some environmental chemical agents. As per American psychological association drug interaction is defined as chemical or physiological reaction that can occur when two different drugs are taken together. Objective: This study was conducted for the detection of various drug interactions in dermatology in a tertiary care teaching hospital. Methods: An observational, prospective study was conducted for a period of six months (July 2017 to December 2017) among 108 patients in dermatology department of Santhiram Medical College and General Hospital, Nandyal. Results: A total of 108 patients were included in the study. Among them, 63 (58.3%) were males and 45(41.7%) were females. Of total 108 prescriptions, sever drug-drug interactions were present in 42 (38.9 %) prescriptions. Whereas, moderate drug-drug interactions were found in 14 (13%) and 52 prescriptions doesn’t have drug-drug interactions respectively. The study found the associations of potential drug interactions with age, sex, number of drugs per prescription. There was a direct link between polypharmacy and occurrence of drug interactions. To lower the frequency of potential interactions it could be necessary to make a careful selection of therapeutic alternatives, and in cases without other options, patients should be continuously monitored to identify adverse events. Conclusion: we concluded that educational interventions can minimize the incidence of drug interactions.


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