scholarly journals A study of drug-drug interactions in cancer patients of a south Indian tertiary care teaching hospital

2011 ◽  
Vol 57 (3) ◽  
pp. 206 ◽  
Author(s):  
G Kannan ◽  
VanithaN Rani ◽  
J Alosh ◽  
JR Martin ◽  
R Anitha ◽  
...  
Keyword(s):  
Drug Interactions ◽  
Cancer Patients ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
South Indian

scholarly journals A STUDY ON THE PREVALENCE AND SEVERITY OF POSSIBLE DRUG-DRUG INTERACTIONS IN PEDIATRICS DEPARTMENT AT AN INDIAN TERTIARY CARE TEACHING HOSPITAL

2018 ◽  
Vol 10 (7) ◽  
pp. 52
Author(s):  
Ramam Sripada ◽  
S. V. Suresh Kumar ◽  
N. Devanna ◽  
Kandula Ravindra Reddy
Keyword(s):  
Drug Interactions ◽  
Pharmaceutical Care ◽  
Teaching Hospital ◽  
Medical Records ◽  
Pediatric Population ◽  
Tertiary Care ◽  
Moderate Severity ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Ambulatory Patients

Objective: To study the prevalence and severity of possible drug-drug interactions in the department of pediatrics.Methods: Case records of the in-patients of the pediatrics department from the medical records department were included and the records of the ambulatory patients were excluded from the study. All the collected cases were subjected to check for the drug-drug interactions by using the software micromedex 2.0 and the interactions were categorized based on the severity into minor, moderate and major.Results: A total of 142 cases were screened for possible drug-drug interactions (DDIs) and among them 76 cases were observed to be with possible DDIs.  The prevalence was found to be 53.5% in this study. Majority of the cases with possible DDIs were observed to be in females. Results of the age wise categorization revealed that majority of the possible DDIS were observed in children (2-12 y) followed by the infants (1 mo–2 y). The drug combinations amikacin+ampicillin, paracetamol+phenytoin and ofloxacin+ondansetron were found to be the frequently observed possible DDIs of minor, moderate and major severities respectively.Conclusion: Majority of the possible DDIs were of moderate severity followed by major. Clinical pharmacists should take the responsibility in assisting the pediatricians for screening the possible DDIs in the prescriptions there by preventing them and providing a better pharmaceutical care for the pediatric population.  

scholarly journals STUDY OF POTENTIAL DRUG INTERACTIONS AMONG EIGHT MAJOR DEPARTMENTS-GENERAL MEDICINE, ORTHOPEDICS, GYNECOLOGY, PULMONOLOGY, GENERAL SURGERY, PSYCHIATRY, OTOLARYNGOLOGY AND DERMATOLOGY OF A TERTIARY CARE TEACHING HOSPITAL IN SOUTHERN INDIA

2020 ◽  
pp. 59-67
Author(s):  
TALHA JABEEN ◽  
MOHD ABDUL KHADER ◽  
A. V. KISHORE BABU ◽  
A. SRINIVASA RAO
Keyword(s):  
Drug Interactions ◽  
Teaching Hospital ◽  
General Surgery ◽  
Tertiary Care ◽  
General Medicine ◽  
Potential Drug ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Study Population ◽  
The Mean

Objective: To identify frequency, type, severity and predictors of potential drug-drug interactions(pDDIs), potential drug-food interactions(pDFIs), potential drug-alcohol interactions(pDAIs) and potential drug-tobacco interactions(pDTIs) and most frequently interacting drug combination pairs in hospitalized patients from departments(depts) of General Medicine(GM), Orthopedic(Ortho), Gynecology(OBG), Pulmonology(Pulmo), General Surgery (GS), Psychiatry (Psych), Otolaryngology(ENT) and Dermatology (Derm) of study population. Methods: A Prospective Observational Study was conducted in eight major dept's of a tertiary care teaching hospital for a period of 6 mo. A sample size of 650 prescriptions reflecting admission no's for each department were used. Results: A total of 650 patients were included in the study. Among them, 282(43.4%) were males and 368(56.6%) were females. The mean age of the study population was 39.67±15.23. A total of 487 pDDIs, 734 pDFIs, 586 pDAIs and 159 pDTIs were found out of 650 hospitalized episodes. OBG showed the highest pDDIs and pDAIs. Highest pDFIs and pDTIs were seen in Pulmo. The majority of DDIs were minor, DFIs and DAIs were moderate and DTIs were of major in severity. Pharmacokinetic types of interactions were seen in the majority of the depts. Logistic regression analysis showed that Polypharmacy was associated with the occurrence of DIs. Most of the DIs repeated several times in particular depts and a list of these combinations was prepared. Conclusion: With the high occurrence of overall DIs and characteristic patterns of DIs combination pairs among different departments of the hospital, the presence of clinical pharmacists in hospitals can play a great role, especially in developing nations like India where their role in hospitalized settings is always controversial.

scholarly journals An Assessment of Anti-hyperglycemic Drug Utilization Patterns and Adherence to AACE/ACE 2015 Guidelines in South Indian Tertiary Care Teaching Hospital

2016 ◽  
Vol 9 (4) ◽  
pp. 225-230
Author(s):  
Siddhartha Nuthakki ◽  
Sivaprasad Pendyala ◽  
Charan Vallabhu ◽  
Naveenbabu Kilaru ◽  
Siva R Challa ◽  
...  
Keyword(s):  
Drug Utilization ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
South Indian ◽  
Utilization Patterns

Assessment of the Sociodemographic Profile, Pattern, and Outcomes of Intentional Poisoning Cases in an Emergency Department of a Tertiary Care Teaching Hospital

Crisis ◽  
2020 ◽  
Vol 41 (6) ◽  
pp. 490-494
Author(s):  
Abhimanyu Parashar ◽  
Madhan Ramesh
Keyword(s):  
Emergency Department ◽  
Teaching Hospital ◽  
Strong Association ◽  
Tertiary Care ◽  
Care Hospital ◽  
Major Health Problem ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
South Indian ◽  
Sociodemographic Profile

Abstract. Background: Intentional self-poisoning has become a major health problem in low- and middle-income countries. Aims: We aimed to assess the sociodemographic profile, pattern, and outcomes of intentional poisoning cases in the emergency department of a tertiary care teaching hospital. Method: A prospective observational study was conducted at the department of emergency medicine of a South Indian tertiary care hospital for 1 year to study the sociodemographic profile, pattern, and outcomes of intentional poisoning cases. Results: The majority of poisonings were observed in the male population (64.5%) and among the age group of 19–40 years (65.2%). Poisoning was prevalent in rural/semi-urban populations (77.5%) and in people engaged in agriculture (28.4%) for their livelihood. Pesticides were the most common agents implicated (65.9%) in poisonings. Based on the Glasgow Coma Scale (GCS) and Poison Severity Scale (PSS), the majority of people with poisoning presented with mild (53.9%) and minor symptoms (36.3%). In 78.5% of the cases, patients recovered while mortality was observed in 5.4% of cases. Conclusion: There was a strong association between outcomes of poisoning and age. Organophosphate pesticides were the most commonly implicated substances in poisonings. Regulation policies should be made by the government to regulate the transport, distribution, and use of insecticides and pesticides.

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