Both Extremes of Arterial Carbon Dioxide Pressure and the Magnitude of Fluctuations in Arterial Carbon Dioxide Pressure Are Associated With Severe Intraventricular Hemorrhage in Preterm Infants

2008 ◽  
Vol 2008 ◽  
pp. 159-160
Author(s):  
S. Shankaran
1980 ◽  
Vol 48 (3) ◽  
pp. 468-472 ◽  
Author(s):  
F. A. Leahy ◽  
D. Cates ◽  
M. MacCallum ◽  
H. Rigatto

To determine 1) the effect of arterial CO2 change on the neonatal cerebral circulation and 2) whether 100% O2 would produce significant decrease in cerebral blood flow (CBF), we studied 24 preterm infants to explain the late (5 min) hyperventilation observed in them during hyperoxia. Of these, 12 were studied before and during inhalation of 2-3% CO2 and 12 before and during the inhalation of 100% O2. We measured CBF by a modification of the venous occlusion plethysmography technique and found that CBF increased 7.8% per Torr alveolar carbon dioxide pressure change and that it decreased 15% with 100% O2. These findings suggest that 1) CO2 is an important regulator of CBF in the perterm infant, 2) CBF-CO2 sensitivity in these infants may be greater than in adult subjects, 3) 100% O2 reduced CBF significantly, and 4) a decrease in CBF during administration of 100% O2 may be at least partially responsible for the increase in ventilation with hyperoxia.


1972 ◽  
Vol 36 (6) ◽  
pp. 714-720 ◽  
Author(s):  
Ronald L. Paul ◽  
Octavio Polanco ◽  
Stephen Z. Turney ◽  
T. Crawford McAslan ◽  
R. Adams Cowley

✓ Cerebral vasomotor responses to alterations in arterial carbon dioxide (PaCO2), as manifested by intraventricular pressure changes, were studied in a group of patients with head injuries. These patients could be classified into three types based on various degrees of responsiveness thought to reflect the integrity of their cerebral vasomotor reactivity.


2006 ◽  
Vol 32 (2) ◽  
pp. 309-312 ◽  
Author(s):  
Pablo Rodriguez ◽  
François Lellouche ◽  
Jerome Aboab ◽  
Christian Brun Buisson ◽  
Laurent Brochard

Author(s):  
Jesús Salvador Sánchez-Díaz ◽  
Karla Gabriela Peniche-Moguel ◽  
Gerardo Rivera-Solís ◽  
Enrique Antonio Martínez-Rodríguez ◽  
Luis Del-Carpio-Orantes ◽  
...  

Introduction. Hemodynamic monitoring of a critically ill patient is an indispensable tool both inside and outside intensive care; we currently have invasive, minimally invasive and non-invasive devices; however, no device has been shown to have a positive impact on the patient's evolution; arterial and venous blood gases provide information on the patient's actual microcirculatory and metabolic status and may be a hemodynamic monitoring tool. Objective. To carry out a non-systematic review of the literature of hemodynamic monitoring carried out through the variables obtained in arterial and venous blood gases. Material and methods. A non-systematic review of the literature was performed in the PubMed, OvidSP and ScienceDirect databases with selection of articles from 2000 to 2019. Results. It was found that there are variables obtained in arterial and venous blood gases such as central venous oxygen saturation (SvcO2), venous-to-arterial carbon dioxide pressure (∆pv-aCO2), venous-to-arterial carbon dioxide pressure/arteriovenous oxygen content difference (∆pv-aCO2/∆Ca-vO2) that are related to cellular oxygenation, cardiac output (CO), microcirculatory veno-arterial flow and anaerobic metabolism and allow to assess tissue perfusion status. Conclusion. The variables obtained by arterial and venous blood gases allow for non-invasive, accessible and affordable hemodynamic monitoring that can guide medical decision-making in critically ill patients.


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