scholarly journals Working Effectively with Multicultural Offenders in a Clinical Context

2021 ◽  
pp. 783-799
Author(s):  
Stephane Shepherd ◽  
Arran Rose ◽  
Mary Madu
Keyword(s):  
Clinical Context

Article Reviews: How Safe Is Surgery for PAH Patients?

2013 ◽  
Vol 12 (1) ◽  
pp. 11-11
Author(s):  
Ioana Preston
Keyword(s):  
Pulmonary Hypertension ◽  
Major Surgery ◽  
Clinical Context ◽  
Prospective Survey ◽  
Published Research

Summaries and commentaries from the section editors and invited reviewers present a clinical context for practitioners' application of the latest published research relevant to the care of patients with pulmonary hypertension. In this issue Ioana Preston, MD, discusses a recently published international, prospective survey of patients with PAH undergoing noncardiac and nonobstetric major surgery.

A Serological Storm

1970 ◽  
Vol 9 (2) ◽  
Author(s):  
Bertha Wong MD ◽  
Maria Bagovich MD ◽  
Ivan Blasutig PhD ◽  
Simon Carette MD MPhil
Keyword(s):  
Differential Diagnosis ◽  
Hepatitis C Virus ◽  
Immune System ◽  
Hepatitis C ◽  
Hcv Infection ◽  
Clinical Context ◽  
Autoantibody Profile ◽  
Life Threatening ◽  
Clinically Significant ◽  
Sensory Polyneuropathy

This article describes a patient presenting with a sensory polyneuropathy and multiple autoantibodies, leading to the diagnosis of hepatitis C virus (HCV) infection. His widely positive autoantibody profile in the absence of clinically significant rheumatic disease illustrates the importance of interpreting autoimmune serology in the appropriate clinical context and the concept of HCV being a non-specific activator of the immune system. In addition, it highlights the importance of considering untreated HCV infection in the differential diagnosis of rheumatic complaints, particularly if the workup reveals multiple autoantibodies, as HCV is a potentially severe and life-threatening disease, which can be appropriately managed with effective antiviral therapy.

scholarly journals Publisher Correction: Author Correction: A patient-centric dataset of images and metadata for identifying melanomas using clinical context

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Veronica Rotemberg ◽  
Nicholas Kurtansky ◽  
Brigid Betz-Stablein ◽  
Liam Caffery ◽  
Emmanouil Chousakos ◽  
...  
Keyword(s):  
Clinical Context ◽  
Patient Centric

A Correction to this paper has been published: https://doi.org/10.1038/s41597-021-00879-x.

scholarly journals Find the Flame: Predictive Biomarkers for Immunotherapy in Melanoma

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1819
Author(s):  
Mattia Garutti ◽  
Serena Bonin ◽  
Silvia Buriolla ◽  
Elisa Bertoli ◽  
Maria Antonietta Pizzichetta ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Tumor Biology ◽  
Predictive Biomarkers ◽  
Decision Making Process ◽  
Checkpoint Inhibition ◽  
Clinical Context ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Therapeutic Landscape

Immunotherapy has revolutionized the therapeutic landscape of melanoma. In particular, checkpoint inhibition has shown to increase long-term outcome, and, in some cases, it can be virtually curative. However, the absence of clinically validated predictive biomarkers is one of the major causes of unpredictable efficacy of immunotherapy. Indeed, the availability of predictive biomarkers could allow a better stratification of patients, suggesting which type of drugs should be used in a certain clinical context and guiding clinicians in escalating or de-escalating therapy. However, the difficulty in obtaining clinically useful predictive biomarkers reflects the deep complexity of tumor biology. Biomarkers can be classified as tumor-intrinsic biomarkers, microenvironment biomarkers, and systemic biomarkers. Herein we review the available literature to classify and describe predictive biomarkers for checkpoint inhibition in melanoma with the aim of helping clinicians in the decision-making process. We also performed a meta-analysis on the predictive value of PDL-1.

scholarly journals Contexts between mental health of fledged people and compassion competence in the care

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
S Steiner
Keyword(s):  
Mental Health ◽  
Asylum Seekers ◽  
Online Survey ◽  
Research Question ◽  
Positive Influence ◽  
Clinical Context ◽  
Doctoral Thesis ◽  
Positive Sense ◽  
Screening Scale

Abstract The aim of this doctoral thesis is to investigate the extent to which the competence compassion has a positive influence on the mental health of refugees. The research question was raised in a first step by means of a questionnaire by Mohr & Müller, ‘Depression tendencies in the non-clinical context’. Eighty asylum seekers were questioned in a total of seventeen lodgings. In addition, a survey was conducted with employees and volunteers in refugee care. This survey included 102 people who were assessed using the standardized BOSS1 Burnout Screening Scale. With the help of the Santa Clara Briefing Scale, the differences in the population between people who are not volunteering and those who volunteer in refugee care are being investigated through an online survey. There were 818 people attending. The evaluation of the data showed that the competency compassion lowers the depressive tendencies among the refugees and they have a more positive sense of integration and hope for a better life. The competency of compassion reduces burnout factors and people who have committed themselves voluntarily have significantly higher values in compassion competency. Thus compassion can be confirmed as a valuable competence in refugee care, not only among the refugees, but also among employees and volunteers. Key messages The present study has shown that empathy skills reduce depressive tendencies in people who have escaped. Associations of compassion and low burnout factors confirmed by the study showed that persons with high compassion skills have low burnout scores.

Superficial CD34-Positive Fibroblastic Tumor

2020 ◽  
Vol 28 (8) ◽  
pp. 879-881
Author(s):  
Oliver Foot ◽  
Magnus Hallin ◽  
Silvia Bagué ◽  
Robin L. Jones ◽  
Khin Thway
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumors ◽  
Good Prognosis ◽  
Differential Diagnoses ◽  
Clinical Context ◽  
Aggressive Tumors

Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described entity that, despite significant pleomorphism, carries a good prognosis. We briefly describe this tumor and its principal differential diagnoses. Recognition of SCPFTs, including the clinical context in which they arise, is important to avoid confusion with other pleomorphic soft tissue tumors, particularly neoplasms in the group of pleomorphic sarcomas, which are typically aggressive tumors that could lead to unnecessary overtreatment.

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