scholarly journals Canadian Association of Neuropathologists L’Association Canadienne des Neuropathologistes

The Canadian Association of Neuropathologists (CANP) held their 57th annual meeting at the Inn at the Forks Hotel in Winnipeg, Manitoba from October 12th-14th, 2017, under the leadership of Dr. Marc Del Bigio, CANP president, who also handled the local arrangements. The annual banquet was held at the Assiniboine Park Conservancy where the polar bears captivated the crowd of Neuropathologists.The academic program of 14 scientific abstracts and 11 unknown cases were compiled by the CANP Secretary-Treasurer Dr. Julia Keith into 4 sessions; Infectious/Immune Mediated and Epilepsy Neuropathology, Tumour Neuropathology, Developmental Neuropathology and Neurodegenerative/Neuromuscular Neuropathology. The program also included a guided interactive forum on Quality Assurance and Professional Affairs for Neuropathologists led by Dr Del Bigio.The digital pathology images from the 11 unknown cases are available for viewing online (www.canp.ca) thanks to the CANP webmaster, Dr. Jason Karamchandani. All submitted abstracts were peer reviewed by the CANP Abstract Review committee comprised of Drs. Marie-Christine Guiot, David Munoz, and Harvey Sarnat.The Presidential Symposium explored the theme of Pediatric Head Injuries and Forensic Neuropathology. Dr. Michael J. Ellis (Section of Neurosurgery, University of Manitoba) delivered an invited lecture entitled Current Concepts in Pediatric Concussion. The Dr. Gordon Mathieson invited member lecturer was Dr. David Ramsay (Western University) who spoke on the subject of Observations on Selected Neuropathological Aspects of Suspected Inflicted Head and Spinal Injury in Young Children. The Dr. David Robertson invited lecture was delivered by Dr. Paul Kadar (Department of Pediatrics, Hospital for Sick Children, University of Toronto) Child Maltreatment/Abusive Head Trauma in a “Pre-” and “Post-Goudge” World. The Dr. Jerzy Olszewski guest lecturer was Dr. Waney Squier (Oxford University, UK) who explained the Impact of Legal Changes in the UK on Brain Retention, Evolving Opinions and Controversies about “Shaken Baby Syndrome”. The symposium concluded with a panel discussion and group Question and Answer session with the symposium speakers.The resident awards committee was comprised of Drs. Sidney Croul and Sherry Krawitz. The Mary Tom Award for best clinical science paper was awarded to Dr. Randy van Ommeren (supervisor Dr. Patrick Shannon) for his presentation of Unknown Case #8 and the Morrison H. Finlayson Award went to Dr. Andrew Gao (supervisor Dr. Lili Hazrati) for his presentation Abstract #14 The Role of ATP and P2X Purinoreceptor 7 in the Pathogenesis of Cerebral Tau.The following abstracts were presented at the 2017 Canadian Association of Neuropathologists (CANP) 57th Annual Meeting in October. The material presented contains the abstracts submitted as part of the 2017 Canadian Association of Neuropathologists (CANP) 57th Annual Meeting, as part of the standard processes of The Canadian Journal of Neurological Sciences, and may contain promotional content that does not represent the views or policies of the journal or publisher. The content and the views expressed therein are those of the presenting entity and not the Editors of The Canadian Journal of Neurological Sciences, the Canadian Neurological Sciences Federation, or Cambridge University Press. Authors have not provided standard disclosure forms as part of their submission, although these would have been evident at the time of the meeting.

Author(s):  
Nova Scotia Halifax

Abstracts and unknown cases presented at the 58th annual meetingThe Canadian Association of Neuropathologists (CANP) held their 58th annual meeting at the Halifax Harbourfront Marriott from October 3rd to 6th, 2018, under the leadership of Dr Marc Del Bigio, CANP president, and Dr. Sidney Croul handled the local arrangements. The annual banquet was held at Chives restaurant in Halifax.The academic program of 20 scientific abstracts and 8 unknown cases was compiled by the CANP Secretary-Treasurer Dr Julia Keith into 5 sessions; I. Traumatic and Neurodegenerative Neuropathology, II. Pediatric, Epilepsy and Miscellaneous Neuropathology, III. Tumour Neuropathology, IV. Infectious/Immune Mediated Neuropathology, and V. Quality Assurance in Neuropathology. The Quality Assurance session included a guided interactive forum led by Dr Marc Del Bigio, and the Neurodegenerative session included an invited talk on Butyrylcholinesterase as a Biomarker for Alzheimer’s Disease by Dr Sultan Darvesh (Faculty of Medicine, Dalhousie University). The digital pathology images from the 8 unknown cases are available for viewing online (www.canp.ca) thanks to the CANP webmaster, Dr Jason Karamchandani.The Presidential Symposium explored the theme of Brain Inflammation. Dr Sean Pittock (Dept of Neurology, Mayo Clinic, Rochester, MN) delivered the Dr Jerzy Olszewski Guest Lecture entitled Neural autoantibody discovery: the new era of autoimmune neurology – out with the old and in with the new! Dr Christian Pagnoux (Vasculitis Clinic, Mount Sinai Hospital, Toronto ON) was an invited speaker who spoke on Vasculitis – effects on the nervous system. Dr Alex Easton (Dept of Pathology, Dalhousie University, Halifax NS) was the Dr Gordon Mathieson invited lecturer speaking about The blood brain barrier and inflammation, and Dr Serge Rivest (Directeur du Centre de Recherche du CHU de Québec, Université Laval, Quebec QC) delivered the Dr David Robertson invited lecture on Microglial roles in human neuropathology. The symposium concluded with a panel discussion and group Question and Answer session with the speakers moderated by Dr Marc Del Bigio.Several trainee awards were handed out. The Dr Mary Tom Award for best clinical science paper was awarded to Dr Maryam Abdollahi (supervisor Dr David Munoz) and the Dr Morrison H. Finlayson Award for best basic science/research paper went to Dr Maliha Khara (Drs Zhou, Wong, Renwick).The following abstracts were presented at the 58th annual meeting of the Canadian Association of Neuropathologists (CANP) in October 2018.


The Canadian Association of Neuropathologist – L’ Association Canadienne de Neuropathologistes (CANP-ACNP) held their 59th annual meeting at the Delta Kingston Waterfront from October 23rd to 26th, 2019, under the leadership of Dr. Peter Gould, President of the CANP-ACNP, Dr. Julia Keith, Secretary Treasurer of the CANP-ACNP, and Dr. John Rossiter, local organizer. The annual banquet was held at River Mill Restaurant in Kingston.The academic program comprised 14 Abstracts, 14 unknown cases, a Symposium on Neurodegenerative Neuropathology, and a Neuropathology Practice lecture by Dr. Gerard Jansen entitled CJD, CJD Surveillance, and Occupational Risk. Can worms ever be re-canned? The interactive forum on Neuropathology Practice was moderated by Dr. Gould and Dr. Keith and focused on safety around autopsy diagnosis of CJD, the Neuropathology workforce analysis in Canada 2019 presented by Dr. Patrick Shannon, and accreditation of neuropathology laboratories in Canada. Digital pathology images from the 14 unknown cases are available for viewing online (www.canp.ca) thanks to the CANP webmaster Dr. Jason Karamchandani.The Presidential Symposium 2019 on Neurodegenerative Neuropathology featured the Jerry Olszewski Lecture given by Dr. Douglas Munoz on Using eye tracking to identify behavioural biomarkers of neurodegeneration, the David Robertson lecture given by Dr. Tom Beach on Staging systems for Lewy body diseases, and the Gordon Mathieson lecture given by Dr. Ian Mackenzie on C9orf72: FTD, ALS and beyond. The program was completed Dr. Gabor Kovacs’ presentation on Tau pathologies in the aging brain and Dr. Carmela Tartaglia’s presentation on Dementia; the times they are a changing.The award for best clinical science presentation by a trainee (Dr. Mary Tom Award) in 2019 went to Dr. Suzy Kosteniuk (Supervisor Dr. Lothar Resch), and the award for best basic science presentation by a trainee (Dr. Morrison H. Finlayson Award) was won by Hoang D. Nguyen (Supervisor Dr. Maxime Richer).The following abstracts were presented at the 59th annual meeting of the Canadian Association of Neuropathologists – Association Candienne des Neuropathologistes (CANP-ACNP) in October 2019.


The Canadian Association of Neuropathologist – Association canadienne des neuropathologistes (CANP-ACNP) held their 60th annual meeting via Zoom from October 15th to 17th, 2020, under the leadership of Dr. Peter Gould, President of the CANP-ACNP, Dr. Peter Schutz, Secretary Treasurer of the CANP-ACNP, and with technical support from CANP administrators Heather Dow and Colleen Fifield.The academic program comprised 10 scientific abstracts, 10 unknown cases, a symposium on Neuromuscular Pathology, and a Neuropathology Practice lecture by Dr. Emina Torlakovic entitled The Fall and Rise of Immunohistochemistry. The interactive forum on Neuropathology Practice was moderated by Dr. Gould and Dr. Keith and focused on forensic neuropathology in Canada. The Jerzy Olszewski Lecture was delivered by Dr. Alex Rajput and Dr. Ali Rajput on Neuropathology and Saskatchewan Movement Disorders Program. Digital pathology images from the 10 unknown cases are available for viewing online (www.canp.ca) thanks to the CANP webmaster Dr. Andrew Gao.The Presidential Symposium 2020 on Neuromuscular Pathology featured the David Robertson Lecture given by Dr. Werner Stenzel entitled The Inflammatory Myopathies – Essential Role of Muscle Biopsies for Precise Diagnosis and the Gordon Mathieson Lecture delivered by Dr. Benjamin Ellezam on The Role of Muscle Biopsy in the Molecular Era: Practical Pointers in Diagnostic Pathology of Inherited Myopathies. The program was completed by Dr. Robert Schmidt’s presentation on Perspectives on the Evaluation of Nerve Biopsies, and Dr. Jodi Warman Chardon’s presentation on MRI & Diagnosis of Muscle Disease.The Mary Tom Award for best clinical science presentation by a trainee went to Dr. Noor Alsafwani (Supervisor Dr. A. Gao), and the Morrison H. Finlayson Award for best basic science presentation by a trainee was won by Dr. Delaney Cosma (Supervisor Dr. R. Hammond).The following abstracts were presented at the 60th annual meeting of the Canadian Association of Neuropathologists – Association candienne des neuropathologistes (CANP-ACNP) in October 2020.


PEDIATRICS ◽  
1995 ◽  
Vol 95 (2) ◽  
pp. 259-262 ◽  
Author(s):  
Suzanne P. Starling ◽  
James R. Holden ◽  
Carole Jenny

Objective. Abusive head trauma is the most common cause of morbidity and mortality in physically abused infants. Effective prevention requires the identification of potential perpetrators. No study has specifically addressed the relationship of the perpetrators of abusive head trauma ("shaken baby syndrome") to their victims. The objectives of this study were to identify the abusers and their relationship to victims in these cases. Methods. We reviewed the medical charts of 151 infants who suffered abusive head trauma to determine the perpetrator of the abuse. Caretakers were classified by level of certainty: confession to the crime, legal actions taken, or strong suspicion by the staff. The relationship of abusers to victims was analyzed. Results. Male victims accounted for 60.3% of the cases. Twenty-three percent of the children died, although death rates for boys and girls did not vary significantly. Male perpetrators outnumbered females 2.2:1, with fathers, step-fathers, and mothers' boyfriends committing over 60% of the crimes. Fathers accounted for 37% of the abusers, followed by boyfriends at 20.5%. Female baby-sitters, at 17.3%, were a large, previously unrecognized group of perpetrators. Mothers were responsible for only 12.6% of our cases. All but one of the confessed abusers were with the child at the time of onset of symptoms. Conclusions. Our data suggest male caretakers are at greater risk to abuse infants. Baby-sitters are a concerning risk group, because they represent a significant proportion of abusers, and they more easily escape prosecution. In addition, no prevention efforts have been directed at baby-sitters. These statistics could help change the focus of efforts to prevent abusive head trauma.


Author(s):  
Sandeep K. Narang ◽  
John David Melville ◽  
Christopher S. Greeley ◽  
James D. Anderst ◽  
Shannon L. Carpenter ◽  
...  

2020 ◽  
Vol 135 (1) ◽  
pp. 235-244
Author(s):  
Katharina Feld ◽  
Dustin Feld ◽  
Bernd Karger ◽  
Janine Helmus ◽  
Nneka Schwimmer-Okike ◽  
...  

AbstractThe shaken baby syndrome (SBS) is a common variant of abusive head trauma (AHT) in infants and toddlers. Data on the legal outcome of such cases are still sparse. By means of a retrospective multi-center analysis, 72 cases of living children diagnosed with SBS/AHT from three German university institutes of legal medicine were identified. Forty-six of these cases with 68 accused individuals were available and could be evaluated with regard to basic data on the course of the criminal proceedings as well as the profile of the defendants (sub-divided into suspects, convicts, and confessed perpetrators). Criminal proceedings predominantly commenced with a complaint by the treating hospital (62%) and were found to be closed (without judgment) in 50% of the cases, mostly due to a “lack of sufficient suspicion.” Of the 23 cases with judgment, the court decided on acquittal in 4 cases (17%). Imprisonment was the most frequent sentence (16 out of 19 cases with conviction, 84%), whereby the sentence has been suspended on probation in 63% of the cases. Suspects and perpetrators were mostly male and derived from the close family environment of the injured children. All confessed perpetrators stated an “excessive demand” as the reason for the violent shaking of the child. The results of the present study are in line with data from other studies with other legal systems. As many criminal proceedings were closed and the 4 acquittals occurred because the perpetration could not be ascribed to a specific perpetrator, improving the forensic methods for such an unequivocal assignment would be desirable.


2013 ◽  
Vol 40 (8) ◽  
pp. 1434-1437 ◽  
Author(s):  
April W. Armstrong ◽  
Joel M. Gelfand ◽  
Wolf-Henning Boehncke ◽  
Ehrin J. Armstrong

At the 2012 annual meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) in Stockholm, Sweden, several GRAPPA members led a panel discussion on cardiovascular (CV) comorbidities of psoriasis and psoriatic arthritis (PsA). The panelists discussed the role of insulin resistance in the pathophysiology of psoriasis, the possible effect of tumor necrosis factor inhibitors on CV comorbidities, and the effect of 12/23 monoclonal antibodies on CV outcomes. The panelists also addressed how lessons from CV comorbidity research could be applied to other areas of comorbidity research in psoriasis and PsA and identified future research directions in this area.


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