scholarly journals A semilethal t-haplotype in the Orkney Islands

1981 ◽  
Vol 37 (3) ◽  
pp. 221-226 ◽  
Author(s):  
G. B. Dooher ◽  
R. J. Berry ◽  
K. Artzt ◽  
D. Bennett
Keyword(s):  
Microscopic Examination ◽  
House Mice ◽  
Island Population ◽  
Isolated Population ◽  
Sterile Male ◽  
Wild Mice ◽  
Orkney Islands ◽  
Histological Characteristics ◽  
Wild House Mice ◽  
T Haplotype

SUMMARYBreeding tests of wild house mice, trapped from an isolated population from Sanday in the Orkney Islands, have demonstrated the presence of a semilethal t-haplotype designated tw106. Microscopic examination of sperm and testes from a sterile male obtained from this population revealed the histological characteristics typical for homozygotes for semilethal t-haplotypes. This report is the first description of the recovery of a t-haplotype from an island population of wild mice.

Retention of the bait marker Rhodamine B in wild house mice

2002 ◽  
Vol 29 (2) ◽  
pp. 159 ◽  
Author(s):  
J. Jacob ◽  
D. A. Jones ◽  
G. R. Singleton
Keyword(s):  
Digestive Tract ◽  
Rhodamine B ◽  
Rapid Screening ◽  
House Mice ◽  
Ambient Light ◽  
Medium Term ◽  
Wild Mice ◽  
Quantitative Results ◽  
Wild House Mice ◽  
Males And Females

We investigated the retention of the systemic bait marker Rhodamine�B (RB) in house mice (Mus domesticus) that were fed RB in pellet bait (0.5% RB) and in water solutions (1.6%). Wild mice fed RB baits (3 mg RB) or provided with treated water (0.3 mg RB) were screened for traces of RB in whiskers, blood, urine, faeces, and the digestive tract. The dye was detectable in all tissues and excretions tested 12 h after its uptake in pellet bait or solution. RB was detectable under ambient light in urine and the digestive tract for up to four days and in faeces for up to two days. RB was detectable in blood sera for up to 84 h using a fluorometer. RB-bands were found in whiskers for up to seven weeks after ingestion of RB. There was no difference between males and females regarding the presence of RB in blood and whiskers. A second dose of RB (1.8 mg) one week after the first dose resulted in two bands in mouse whiskers. Fewer mice were scored RB positive when uptake of RB was low. In contrast to whiskers, analysis of blood sera provided quantitative results and allowed rapid screening of animals. We conclude that RB is an appropriate marker for short- and medium-term studies on bait uptake in house mice.

scholarly journals Acute oral toxicity of zinc phosphide: an assessment for wild house mice in Australia

2021 ◽  
Author(s):  
Lyn A Hinds ◽  
Steve Henry ◽  
Nikki Van de Weyer ◽  
Freya Robinson ◽  
Wendy A Ruscoe ◽  
...  
Keyword(s):  
Lethal Dose ◽  
Laboratory Strain ◽  
Zinc Phosphide ◽  
Alternative Food ◽  
House Mice ◽  
Oral Toxicity ◽  
Oral Gavage ◽  
Wild Mice ◽  
Time To Death ◽  
Wild House Mice

BACKGROUND: The efficacy of zinc phosphide (ZnP) for broadacre control of wild house mice in Australia is being reported by growers as increasingly variable. Have mice become less sensitive over time or are they taking a sub-lethal dose and developing aversion? In this laboratory study the sensitivity of groups of wild caught and an outbred laboratory strain of mice was assessed using oral gavage of a range of ZnP concentrations. The willingness of mice to consume ZnP-coated grains was then determined. RESULTS: Each mouse group had very similar LD50 values (72 to 79 mg ZnP per kg body weight) which are significantly higher than previously reported. Time to death post-gavage ranged between 2.5 to 48 h. ZnP coated grains (50 mg ZnP per kg grain) presented in the absence of alternative food were consumed and 94 percent of wild mice died. Mice provided with alternative food and ZnP coated wheat grains (either 25 or 50 mg ZnP per kg grain) consumed toxic and non-toxic grains, and mortality was lower (33 to 55 percent). If a sublethal amount of ZnP coated grain was consumed, aversion occurred mostly in the presence of alternative food. CONCLUSIONS: The sensitivity of wild house mice to ZnP in Australia is significantly lower than previously assumed. Under laboratory conditions ZnP coated grains coated with a new higher dose (50 mg ZnP per kg grain) were readily consumed. Consumption of toxic grain occurred when alternative food was available but was decreased. It is important to assess the efficacy of the higher ZnP dose per grain under natural field conditions, especially when background food is low.

scholarly journals Evolution of Boldness and Exploratory Behavior in Giant Mice from Gough Island

2020 ◽  
Author(s):  
Jered A. Stratton ◽  
Mark J. Nolte ◽  
Bret A. Payseur
Keyword(s):  
Inbred Strains ◽  
House Mice ◽  
Island Population ◽  
Phenotypic Evolution ◽  
Behavioral Evolution ◽  
Island Populations ◽  
Recessive Mutations ◽  
Gough Island ◽  
Wild House Mice ◽  
Common Laboratory

AbstractIsland populations are hallmarks of extreme phenotypic evolution. Radical changes in resource availability and predation risk accompanying island colonization drive changes in behavior, which Darwin likened to tameness in domesticated animals. Although many examples of animal boldness are found on islands, the heritability of observed behaviors, a requirement for evolution, remains largely unknown. To fill this gap, we profiled anxiety and exploration in island and mainland inbred strains of house mice raised in a common laboratory environment. The island strain was descended from mice on Gough Island, the largest wild house mice on record. Experiments utilizing open environments across two ages showed that Gough Island mice are bolder and more exploratory, even when a shelter is provided. Concurrently, Gough Island mice retain an avoidance response to predator urine. F1 offspring from crosses between these two strains behave more similarly to the mainland strain for most traits, suggesting recessive mutations contributed to behavioral evolution on the island. Our results provide a rare example of novel, inherited behaviors in an island population and demonstrate that behavioral evolution can be specific to different forms of perceived danger. Our discoveries pave the way for a genetic understanding of how island populations evolve unusual behaviors.

scholarly journals Breeding and handling small wild rodents: a method study

1969 ◽  
Vol 3 (2) ◽  
pp. 107-117 ◽  
Author(s):  
Margaret E. Wallace ◽  
Christine A. Hudson
Keyword(s):  
Mus Musculus ◽  
House Mice ◽  
Wild Rodents ◽  
Breeding Performance ◽  
Wild Mice ◽  
Wild House Mice ◽  
Cleaning Methods

Breeding, handling and cleaning methods for wild house mice ( Mus musculus) are described. In the absence of measures of efficiency in the literature for wild rodents in general, measures of breeding performance and of time needed for handling and cleaning are proposed; figures for these measures are given for the cage, chute and methods here described in reference to wild mice.

Effects of radio collars on wild mice, Mus domesticus

1990 ◽  
Vol 68 (7) ◽  
pp. 1607-1609 ◽  
Author(s):  
Odile Pouliquen ◽  
Michelle Leishman ◽  
Trevor D. Redhead
Keyword(s):  
Adverse Effects ◽  
Social Interactions ◽  
Small Mammals ◽  
House Mice ◽  
Mus Domesticus ◽  
Wild Animals ◽  
Wild Mice ◽  
Wild House Mice

Experiments were conducted in the laboratory and in the field to test the effects of radio collars (1.7–1.9 g) on wild house mice (Mus domesticus). There was a decrease in the activity of the collared animals in the laboratory immediately after collar attachment. There were no adverse effects on social interactions in the laboratory, nor on survival for 4–5 days in the field. Provided that the collar is well adjusted, there should be no need to keep wild animals captive for more than 1 h after collar attachment. These results are consistent with those of other researchers on the effect of transmitters on some species of small mammals.

Female Preference and Variability Among t-Haplotypes in Wild House Mice

1994 ◽  
Vol 143 (5) ◽  
pp. 766-784 ◽  
Author(s):  
Sarah Lenington ◽  
Carol B. Coopersmith ◽  
Mark Erhart
Keyword(s):  
Female Preference ◽  
House Mice ◽  
Wild House Mice

scholarly journals A SECOND GROUP OF SIMILAR LETHALS IN POPULATIONS OF WILD HOUSE MICE

Genetics ◽  
1959 ◽  
Vol 44 (5) ◽  
pp. 795-802 ◽  
Author(s):  
Dorothea Bennett ◽  
L C Dunn ◽  
Susan Badenhausen
Keyword(s):  
House Mice ◽  
Wild House Mice

scholarly journals Insights into mammalian biology from the wild house mouse Mus musculus

eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Megan Phifer-Rixey ◽  
Michael W Nachman
Keyword(s):  
House Mouse ◽  
Mus Musculus ◽  
Genetic Model ◽  
Inbred Strains ◽  
Mendelian Inheritance ◽  
Model Organisms ◽  
House Mice ◽  
Small Subset ◽  
Wild Mice ◽  
Wide Range

The house mouse, Mus musculus, was established in the early 1900s as one of the first genetic model organisms owing to its short generation time, comparatively large litters, ease of husbandry, and visible phenotypic variants. For these reasons and because they are mammals, house mice are well suited to serve as models for human phenotypes and disease. House mice in the wild consist of at least three distinct subspecies and harbor extensive genetic and phenotypic variation both within and between these subspecies. Wild mice have been used to study a wide range of biological processes, including immunity, cancer, male sterility, adaptive evolution, and non-Mendelian inheritance. Despite the extensive variation that exists among wild mice, classical laboratory strains are derived from a limited set of founders and thus contain only a small subset of this variation. Continued efforts to study wild house mice and to create new inbred strains from wild populations have the potential to strengthen house mice as a model system.

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