Endogenous Growth, Trend Output, and the Industrial Revolution: Reply to Crafts and Mills

1997 ◽  
Vol 57 (4) ◽  
pp. 957-960 ◽  
Author(s):  
David Greasley ◽  
Les Oxley
Keyword(s):  
Endogenous Growth ◽  
Industrial Revolution ◽  
Alternative View ◽  
Industrial Output ◽  
Long Term Effects ◽  
Growth Trend ◽  
Important Paper ◽  
Parsimonious Models ◽  
Stochastic Properties

The origins of this exchange stem from an important paper by N. F. R. Crafts, Steven Leybourne, and Terence Mills, which argues that underlying trends in British industrial output for the period 1700 to 1913 are stochastic rather than linearly deterministic. Using parsimonious methods, we propose an alternative view that the output series have alternating stochastic properties. Specifically we distinguish the period 1780 to 1851 as an Industrial Revolution epoch during which shocks had long-term effects. Out model simplifies to help understand the complexities of the Industrial Revolution, and we agree with Clive Granger and Zhuanxin Ding, that “While it is correct to search over a specific set of parsimonious models … the model so achieved is, at best, an approximation to the truth”.

scholarly journals PSYCHOLOGICAL RECURRENCES AND INTERVENTION PROPOSAL FOR PATIENTS FOLLOWING BARIATRIC SURGERY

2013 ◽  
Vol 5 (1) ◽  
pp. 89-95
Author(s):  
Aída M. Reséndiz Barragán ◽  
Mariana A. Sierra Murguía
Keyword(s):  
Bariatric Surgery ◽  
Psychological Intervention ◽  
World Health ◽  
Long Term Results ◽  
Long Term Effects ◽  
Growth Trend ◽  
Behavioral Group ◽  
Health Organization ◽  
Post Bariatric Surgery

Obesity has been declared by the World Health Organization (WHO) as an epidemic, due to a growth trend in obesity rates over the past 60 years and it is estimated that by 2015 there will be approximately 2.3 billion overweighed adults and 700 million obese adults worldwide. Bariatric surgery has shown to be the most effective intervention for the treatment of severe obesity with better long-term results. While most post-operative patients of bariatric surgery show improvement in psychopathology and quality of life, psychological recurrences have been identified thereafter. It has been reported that for people who have not been able to implement changes in their lifestyle, the result of the operation may not be optimal and may even be counterproductive with undesirable outcomes, such as recovery of lost weight, malnutrition, depression and anxiety, as well as using food as a soothing agent to stressful stimuli, present failures in following the diet, as well as dissatisfaction with the staff of the clinic In recent years the number of bariatric surgeries performed annually has tripled showing a tendency to continue increasing, psychosocial and behavioral factors play a fundamental role in the long- term effects of the surgery; for this reason, the objective of this study is to describe the main psychological recurrences after bariatric surgery as well as a proposal for post-surgical cognitive behavioral group psychological support. Key words: bariatric surgery, obesity, post bariatric surgery, psychological intervention.

The Atlantic Slave Trade and its Lasting Impact

2018 ◽  
pp. 59-75
Author(s):  
Wasiq Khan
Keyword(s):  
Industrial Revolution ◽  
Slave Trade ◽  
Academic Research ◽  
Long Term Effects ◽  
Slave Labor ◽  
Source Regions ◽  
Transatlantic Trade ◽  
Economic Motives ◽  
Second World

This chapter describes aspects of the transatlantic slave trade specific to regions that now comprise Nigeria and provides a review of academic research since the Second World War on the causes, effects, and character of the trade. Because of its volume, duration, and destabilizing effects, the trade had a profound impact on Nigeria’s political and economic evolution. Modern scholarship has centered around five recurring questions: How large was the trade? How efficient and productive was slave labor relative to free labor? Did the trade catalyze the Industrial Revolution in England? Did the trade retard the long-term economic development of Africa? Why did Africa, as opposed to many other potential source regions, become the New World’s primary provider of slave labor? Despite decades of research and scholarly debate, questions about the economic motives for the transatlantic trade and its long-term effects on Africa’s development remain unsettled.

scholarly journals Exploring the Concepts of Abuse and Neglect of Children in Victorian Novel: A Revisitation of Dickens’ Works

2019 ◽  
Vol 5 (09) ◽  
Author(s):  
Ibrahim YEKINI
Keyword(s):  
Industrial Revolution ◽  
Physical Violence ◽  
Well Being ◽  
Self Esteem ◽  
Victorian Novel ◽  
Long Term Effects ◽  
Deep Impact ◽  
Self Image ◽  
Abuse And Neglect

The long term abuse of children, physically, emotionally, sexually or through neglect can have major long-term effects on all aspects of a child's health, development and well-being. This emotional violence is likely to have a deep impact on the child's self-image and self-esteem, and on his or her future life. This article is a critical exploration of Charles Dickens’ novels, Oliver Twist and David Copperfield that has been slightly adapted from my doctoral dissertation, to pinpoint aspects of moral and physical violence Victorian children are exposed to during the Industrial Revolution in England, in order to examine its impacts on their emotional development and make suggestions for a sustained solutions to the same plights devastating African children.

The epidemic of COVID-19 prompted widespread use of mRNA vaccinations

2021 ◽  
Author(s):  
Moataz Dowaidar
Keyword(s):  
Industrial Revolution ◽  
Genetic Diseases ◽  
Phase Iii ◽  
Significant Shift ◽  
Long Term Effects ◽  
The Enlightenment ◽  
Number Of Patients ◽  
Distribution Limits ◽  
Extrahepatic Tissues

COVID-19 challenge resulted in huge expenditure in mRNA-lipid-based nanoparticles (LNPs) manufacturing. Hundreds of billions are produced for human use. This is a significant shift, inconceivable only a year ago. If an LNP platform can traverse thick mucus in patients with respiratory difficulties (such as cystic fibrosis) or target extrahepatic tissues in the future, multi-billion-dose procedures are in place to serve a significant number of patients with unusual genetic diseases (>100,000 individuals). Due to LNPs' versatility in delivering genome editing components, a successful strategy might be easily scaled up and employed to successfully eliminate a rare disease with a single treatment.COVID-19 led to widespread usage of mRNA vaccines. For years, academic and industrial scientists have worked intensely to produce these technologies. Although not enough time to analyze the long-term effects of mRNA vaccines, phase III clinical studies of Pfizer/BioNTech and Moderna vaccines showed around 95 percent efficacy and outstanding safety profiles. The COVID-19 outbreak laid the stage for scaling and overcoming distribution limits that would otherwise have taken decades. RNA treatments and nanomedicine as a field will never be the same again, and will take center stage. The Enlightenment Age of the RNA nanotherapeutics sector is coming to an end, and the area is ready for a full-scale industrial revolution.

Ovarian Dysfunction in Fetally Irradiated Beagles

1977 ◽  
Vol 35 ◽  
pp. 658-659
Author(s):  
T. M. Seed ◽  
M. H. Sanderson ◽  
D. L. Gutzeit ◽  
T. E. Fritz ◽  
D. V. Tolle ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Long Term Effects ◽  
Ovarian Dysfunction ◽  
Dose Rates ◽  
Highly Sensitive ◽  
Microscopic Evaluation ◽  
Ovarian Pathology ◽  
Normal Offspring

The developing mammalian fetus is thought to be highly sensitive to ionizing radiation. However, dose, dose-rate relationships are not well established, especially the long term effects of protracted, low-dose exposure. A previous report (1) has indicated that bred beagle bitches exposed to daily doses of 5 to 35 R 60Co gamma rays throughout gestation can produce viable, seemingly normal offspring. Puppies irradiated in utero are distinguishable from controls only by their smaller size, dental abnormalities, and, in adulthood, by their inability to bear young.We report here our preliminary microscopic evaluation of ovarian pathology in young pups continuously irradiated throughout gestation at daily (22 h/day) dose rates of either 0.4, 1.0, 2.5, or 5.0 R/day of gamma rays from an attenuated 60Co source. Pups from non-irradiated bitches served as controls. Experimental animals were evaluated clinically and hematologically (control + 5.0 R/day pups) at regular intervals.

Ultrastructural investigations of MDL 19,660-induced effects on the canine platelet and megakaryocyte

1990 ◽  
Vol 48 (3) ◽  
pp. 374-375
Author(s):  
D.E. Loudy ◽  
J. Sprinkle-Cavallo ◽  
J.T. Yarrington ◽  
F.Y. Thompson ◽  
J.P. Gibson
Keyword(s):  
Antidepressant Drug ◽  
Beagle Dogs ◽  
Long Term Effects ◽  
Short Term ◽  
Platelet Counts ◽  
Toxicological Studies ◽  
Induced Aggregation ◽  
Internal Architecture

Previous short term toxicological studies of one to two weeks duration have demonstrated that MDL 19,660 (5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3Hl, 2,4-triazole-3-thione), an antidepressant drug, causes a dose-related thrombocytopenia in dogs. Platelet counts started to decline after two days of dosing with 30 mg/kg/day and continued to decrease to their lowest levels by 5-7 days. The loss in platelets was primarily of the small discoid subpopulation. In vitro studies have also indicated that MDL 19,660: does not spontaneously aggregate canine platelets and has moderate antiaggregating properties by inhibiting ADP-induced aggregation. The objectives of the present investigation of MDL 19,660 were to evaluate ultrastructurally long term effects on platelet internal architecture and changes in subpopulations of platelets and megakaryocytes.Nine male and nine female beagle dogs were divided equally into three groups and were administered orally 0, 15, or 30 mg/kg/day of MDL 19,660 for three months. Compared to a control platelet range of 353,000- 452,000/μl, a doserelated thrombocytopenia reached a maximum severity of an average of 135,000/μl for the 15 mg/kg/day dogs after two weeks and 81,000/μl for the 30 mg/kg/day dogs after one week.

Long-Term Effects of Head Lice Tx Unknown

2012 ◽  
Vol 43 (3) ◽  
pp. 42
Author(s):  
MITCHEL L. ZOLER
Keyword(s):  
Head Lice ◽  
Long Term Effects

The response of skin perfusion and of rheological and immunological variables to intravenous prostanoid administration in Raynaud’s phenomenon secondary to collagenosis

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 243-249 ◽  
Author(s):  
Drinda ◽  
Neumann ◽  
Pöhlmann ◽  
Vogelsang ◽  
Stein ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Plasma Viscosity ◽  
Laser Doppler ◽  
Erythrocyte Aggregation ◽  
Control Group ◽  
Long Term Effects ◽  
Doppler Flowmetry

Background: Prostanoids are used in the treatment of Raynaud’s phenomenon and acral perfusion disorders secondary to collagenosis. In subjective terms, intravenous administration of these agents produces success in more than 50% of patients. The therapeutic outcome of clinical administration of alprostadil or iloprost may vary from individual to individual. Patients and methods: The following variables were analysed in a cross-over study in 27 patients with collagenosis and Raynaud’s phenomenon: plasma viscosity and erythrocyte aggregation (rheological variables), partial pressure of oxygen and laser Doppler flowmetry in the finger region, and lymphocyte phenotyping and interleukin (IL) determinations (immunological variables). Results: Laser Doppler flowmetry revealed significant differences between patients with secondary Raynaud’s phenomenon and a control group of 25 healthy subjects. Laser Doppler readings did not change significantly as a result of the treatments. Therapy with iloprost produced a reduction in IL-1beta, L-selectin (CD 62 L) and IL-6. Conclusion: The change in immunological variables due to iloprost may explain the long-term effects of prostaglandins in the treatment of Raynaud’s phenomenon. From our results it is not possible to infer any preference for iloprost or alprostadil.

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