Radiological study of primary spontaneous CSF rhinorrhoea

1991 ◽  
Vol 105 (4) ◽  
pp. 274-277 ◽  
Author(s):  
N. S. Tolley ◽  
G. A. S. Lloyd ◽  
H. O. L. Williams

AbstractA radiological study of skull base anatomy was performed in patients presenting with primary spontaneous CSF rhinorrhoea. Radiology correctly identified the fistula site in 90 per cent of cases. Contrast CT imaging was found to be the most suitable technique for identifying the presence and site of CSF fistulae. However, pre-contrast bony dehiscences were identified in all patients leaking from the cribriform plate region. More significantly, all of these patients showed deviation of their crista galli, a radiological sign hitherto unreported. These findings support the theory that congenital bony dehiscence is the aetiological basis for this condition. The importance of radiology in the management of this condition is emphasized.

2014 ◽  
Vol 75 (S 02) ◽  
Author(s):  
Gerlig Widmann ◽  
P. Schullian ◽  
R. Hoermann ◽  
E. Gassner ◽  
H. Riechelmann ◽  
...  

2020 ◽  
Author(s):  
Christopher Pool ◽  
Roshan Nayak ◽  
Meghan Wilson

Author(s):  
Danyal Z. Khan ◽  
Hani J. Marcus ◽  
Hugo Layard Horsfall ◽  
Soham Bandyopadhyay ◽  
Benjamin E. Schroeder ◽  
...  

2021 ◽  
pp. 194589242110205
Author(s):  
Gian Luca Fadda ◽  
Alessio Petrelli ◽  
Federica Martino ◽  
Giovanni Succo ◽  
Paolo Castelnuovo ◽  
...  

Background Recent developments in endoscopic sinus surgery (ESS) have increased the need to investigate the complex anatomic variations in the ethmoid roof and skull base, to inform the surgeon about the risk of damaging these crucial areas during ESS. Objective To offer a detailed description of sinus anatomy focusing on the key surgical landmarks in ESS and frontal recess surgery to standardize a systematic approach during the preoperative sinuses imaging evaluation. Methodology: A total of 220 computed tomography (CT) scans were reviewed to obtain six sets of measurements: the depth of the cribriform plate (CP); the length of the lateral lamella of the cribriform plate (LLCP); the angle formed by the LLCP and the continuation of the horizontal plane passing through the CP; the position of the anterior ethmoidal artery (AEA) at the skull base; the extent of frontal sinus pneumatization (FSP); the type of superior attachment of the uncinate process (SAUP). Results The length of the LLCP was statistically significantly correlated with the different Keros classification types, the angle formed by the LLCP with the continuation of the horizontal plane passing through the CP, and with the AEA position at the skull base. The depth of the olfactory fossa was correlated with FSP. Conclusions According to the Keros and Gera classifications, the data obtained from these evaluations allow the assessment of anatomic-radiological risk profiles and can help identify those patients who are high risk for ethmoid roof injury.


2009 ◽  
pp. 53-57
Author(s):  
M. Tschabitscher ◽  
R. J. Galzio

2017 ◽  
Vol 31 (04) ◽  
pp. 177-188 ◽  
Author(s):  
Soroush Farnoosh ◽  
Robert Kellman ◽  
Sherard Tatum ◽  
Jacob Feldman

AbstractTraumatic injuries to the skull base can involve critical neurovascular structures and present with symptoms and signs that must be recognized by physicians tasked with management of trauma patients. This article provides a review of skull base anatomy and outlines demographic features in skull base trauma. The manifestations of various skull base injuries, including CSF leaks, facial paralysis, anosmia, and cranial nerve injury, are discussed, as are appropriate diagnostic and radiographic testing in patients with such injuries. While conservative management is sometimes appropriate in skull base trauma, surgical access to the skull base for reconstruction of traumatic injuries may be required. A variety of specific surgical approaches to the anterior cranial fossa are discussed, including the classic anterior craniofacial approach as well as less invasive and newer endoscope-assisted approaches to the traumatized skull base.


2019 ◽  
Vol 47 (9) ◽  
pp. e774-e781 ◽  
Author(s):  
Ludovic Broche ◽  
Pauline Pisa ◽  
Liisa Porra ◽  
Loïc Degrugilliers ◽  
Alberto Bravin ◽  
...  

2019 ◽  
Vol 129 ◽  
pp. 372-377 ◽  
Author(s):  
Ioannis Kournoutas ◽  
Vera Vigo ◽  
Ricky Chae ◽  
Minghao Wang ◽  
Jose Gurrola ◽  
...  

2019 ◽  
Vol 34 (3) ◽  
pp. 342-347
Author(s):  
John P. Flynn ◽  
Anna Pavelonis ◽  
Luke Ledbetter ◽  
Vidur Bhalla ◽  
Sameer A. Alvi ◽  
...  

Background Intrathecal fluorescein (IF) has become a common tool for localization of cerebrospinal fluid (CSF) leak, but despite frequent use, IF lacks Food and Drug Administration approval. The diagnostic ability of high-resolution computed tomography (HRCT) has increased over several decades. Subspecialized rhinology training within otolaryngology has, similarly, allowed for dedicated skull base surgeons to become more adept at CSF leak localization. Objectives To evaluate the utility of HRCT and IF in CSF leak localization. To identify certain patient populations in which IF has added utility. To analyze the ability of fellowship-trained neuroradiologist and rhinologist to localize CSF leak sites. Methods Data were collected from a single, tertiary care academic institution. Patients admitted for CSF leak between 2003 and 2016 were included. Diagnostic yield of preoperative imaging and IF for identification of leak site was analyzed. Fellowship-trained neuroradiologist and rhinologist performed retrospective review of CT imaging and identified CSF leak sites. Results One hundred and two patients underwent CSF leak repair. Skull base defects were preoperatively localized to exact sinus on imaging report in 67% of patients. Preoperative imaging stratified by CT slice thickness of 0.625 mm identified leak site in 88.9% of cases. Blinded retrospective review by a neuroradiologist and rhinologist was able to localize the CSF leak to the correct or adjacent sinus in >80% of cases. IF was useful for intraoperative localization in 73% of cases. When preoperative imaging failed at leak site localization, IF was able to correctly identify leak site in 75% of cases. Conclusions The diagnostic yield of IF and CT imaging was equivalent, with each modality localizing leak site approximately two-thirds of the time. CT imaging with 0.625 mm slice thickness proved more efficacious in identification of skull base defects. IF demonstrated increased utility in instances where preoperative imaging has failed at leak site identification.


2018 ◽  
Vol 19 (01) ◽  
pp. 1850043 ◽  
Author(s):  
Samireh Badrigilan ◽  
Behrouz Shaabani ◽  
Nahideh Ghareh Aghaji ◽  
Asghar Mesbahi

By integrating high-performance CT imaging and photothermal therapy (PTT) into one nanoprobe, an effective theranostic can be achieved for clinical cancer treatment. In this study, the graphene quantum dots (GQDs)-coated bismuth (Bi) nanoparticle (NP) as a theranostic nanoprobe is synthesized and its capabilities for computed tomography (CT) imaging and PTT are investigated. Such nanotheranostic exhibits good physiological dispersity with satisfactory blood compatibility and cytotoxicity. Most importantly, the GQDs-Bi NPs offer strong and steady absorbance profile in NIR region with excellent photostability, which can remarkably convert photo-to-thermal with the photothermal efficiency of 30.0%. Thanks to the powerful PTT effect, co-delivery of GQDs-Bi NPs/NIR laser can effectively induce HeLa cells death in vitro. Cooperatively, NPs hold X-ray attenuation coefficient for high-contrast CT imaging with the corresponding CT improvement efficacy as high as 32.7[Formula: see text]HU[Formula: see text]mg[Formula: see text]. The obtained results highlight the potential of GQDs-Bi NPs as a successful theranostic nanoagent for CT imaging and cancer photothermal therapy.


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