Horizontal sound localisation and speech perception in Bonebridge-implanted single-sided deafness patients

2020 ◽  
Vol 134 (9) ◽  
pp. 814-821
Author(s):  
C Zhao ◽  
J Yang ◽  
Y Liu ◽  
M Gao ◽  
P Chen ◽  
...  
Keyword(s):  
Speech Perception ◽  
Speech Intelligibility ◽  
Contralateral Side ◽  
Side Condition ◽  
Sound Localisation ◽  
Single Centre Study ◽  
Long Term Follow Up ◽  
Single Sided Deafness ◽  
Study Participants

AbstractObjectiveThis study aimed to investigate the benefit of Bonebridge devices in patients with single-sided deafness.MethodFive patients with single-sided deafness who were implanted with Bonebridge devices were recruited in a single-centre study. Participants’ speech perception and horizontal sound localisation abilities were assessed at 6 and 12 months post-operatively. Speech intelligibility in noisy environments was measured in three different testing conditions (speech and noise presented from the front, speech and noise presented from the front and contralateral (normal ear) side separately, and speech presented from the ipsilateral (implanted Bonebridge) side and noise from the contralateral side). Sound localisation was evaluated in Bonebridge-aided and Bonebridge-unaided conditions at different stimuli levels (65, 70 and 75 dB SPL).ResultsAll participants showed a better capacity for speech intelligibility in quiet environments with the Bonebridge device. The speech recognition threshold with the Bonebridge device was significantly decreased at both short- and long-term follow up in the speech presented from the ipsilateral (implanted Bonebridge) side and noise from the contralateral side condition (p < 0.05). Additionally, participants maintained similar levels of sound localisation between the Bonebridge-aided and unaided conditions (p > 0.05). However, the accuracy of localisation showed some improvement at 70 dB SPL and 75 dB SPL post-operatively.ConclusionThe Bonebridge device provides the benefit of improved speech perception performance in patients with single-sided deafness. Sound localisation abilities were neither improved nor worsened with Bonebridge implantation at the follow-up assessments.

scholarly journals Bone-anchored hearing system, contralateral routing of signals hearing aid or cochlear implant: what is best in single-sided deafness?

2021 ◽  
Author(s):  
Till F. Jakob ◽  
Iva Speck ◽  
Ann-Kathrin Rauch ◽  
Frederike Hassepass ◽  
Manuel C. Ketterer ◽  
...  
Keyword(s):  
Speech Perception ◽  
Cochlear Implant ◽  
Hearing Aids ◽  
Long Term Results ◽  
Speech Perception In Noise ◽  
Sound Localisation ◽  
Therapy Option ◽  
Single Sided Deafness ◽  
Objective Hearing Tests

Abstract Purpose The aim of the study was to compare long-term results after 1 year in patients with single-sided deafness (SSD) who were fitted with different hearing aids. The participants tested contralateral routing of signals (CROS) hearing aids and bone-anchored hearing systems (BAHS). They were also informed about the possibility of a cochlear implant (CI) and chose one of the three devices. We also investigated which factors influenced the choice of device. Methods Prospective study with 89 SSD participants who were divided into three groups by choosing BAHS, CROS, or CI. All participants received test batteries with both objective hearing tests (speech perception in noise and sound localisation) and subjective questionnaires. Results 16 participants opted for BAHS-, 13 for CROS- and 30 for CI-treatment. The greater the subjective impairment caused by SSD, the more likely patients were to opt for surgical treatment (BAHS or CI). The best results in terms of speech perception in noise (especially when sound reaches the deaf ear and noise the hearing ear), sound localization, and subjective results were achieved with CI. Conclusion The best results regarding the therapy of SSD are achieved with a CI, followed by BAHS. This was evident both in objective tests and in the subjective questionnaires. Nevertheless, an individual decision is required in each case as to which SSD therapy option is best for the patient. Above all, the patient's subjective impairment and expectations should be included in the decision-making process.

Long-term Outcomes of Clip Coupler Implantation in Patients with Unilateral Congenital Aural Atresia

2020 ◽  
Vol 129 (12) ◽  
pp. 1221-1228
Author(s):  
Chunli Zhao ◽  
Jinsong Yang ◽  
Yujie Liu ◽  
Mengdie Gao ◽  
Peiwei Chen ◽  
...  
Keyword(s):  
Speech Intelligibility ◽  
Signal To Noise Ratio ◽  
Bone Conduction ◽  
Free Field ◽  
Short Term ◽  
Aural Atresia ◽  
Long Term Follow Up ◽  
Congenital Aural Atresia

Objective: To evaluate the long-term safety and efficacy of the Clip coupler attached to the stapes head in patients with unilateral congenital aural atresia (CAA). Methods: This single-center retrospective study included 16 Mandarin-speaking patients who had unilateral microtia accompanied by CAA. All patients were divided into two groups: the short-term follow-up group (n = 9) and the long-term follow-up group (n = 7). The floating mass transducer of the Vibrant Soundbridge (VSB) was positioned in the stapes head by the Clip coupler. The safety of the VSB was investigated by comparing preoperative and postoperative bone-conduction (BC) thresholds as well as by complications. The effectiveness was evaluated by functional gain (FG), word recognition score (WRS), speech reception threshold (SRT) and signal-to-noise ratio (SNR). Results: Pre- and post-operative BC thresholds were no different in all patients. And no complications developed. VSB-aided thresholds in the free-field had improved significantly in both short- and long-term follow-up groups. The improvements of WRS were observed in two groups. The monosyllabic VSB-aided WRS in the long-term follow-up group was significantly higher than that in the short-term follow-up group. When speech was from the impaired ear and noise presented to the side of normal ear (SVSBNCL), lower SNRs were found in two groups after VSB implantation. However, there was no statistical difference in aided SNR between the two groups at SVSBNCL status. Conclusions: Our results show that the FMT connected to the stapes head is a secure and useful device for patients with unilateral CHL/MHL, not only in terms of improved hearing thresholds, but also improved speech intelligibility in quiet and noisy environments.

scholarly journals Cochlear Implants in Single-Sided Deafness. Comparison Between Children and Adult Populations With Post-lingually Acquired Severe to Profound Hearing Loss

2021 ◽  
Vol 12 ◽  
Author(s):  
Nadia Falcón Benítez ◽  
Juan Carlos Falcón González ◽  
Ángel Ramos Macías ◽  
Silvia Borkoski Barreiro ◽  
Ángel Ramos de Miguel
Keyword(s):  
Hearing Loss ◽  
Speech Perception ◽  
Cochlear Implantation ◽  
Speech Test ◽  
Deaf Adults ◽  
Common Etiology ◽  
Single Sided Deafness ◽  
Positive Results ◽  
Auditory Lateralization

Objective: To determine audiological and clinical results of cochlear implantation (CI) comparing two populations with single-sided deafness (SSD): post-lingually deaf children between 6 and 12 years of age, and post-lingually deaf adults, in order to evaluate the effect of CI in different age groups.Design: Retrospective case review.Setting: Tertiary clinic.Patients and Method: Twenty-three children and twenty-one adult patients that were candidates for CI with single-side deafness were included. In all cases we evaluate: Speech perception thresholds; disyllabic words test (65 dB SPL) were performed in the modalities S0–SCI–SNH and Auditory Lateralization Test. The Speech, Spatial, and Qualities of Hearing Scale (SSQ) questionnaire was also used. All results were obtained after 12 months of CI activation.Results: In children, the most common etiology was idiopathic sensory-neural hearing loss. They showed positive results in the Auditory Lateralization Test. In the Speech Test, word recognition in noise improved from 2% preoperatively to 61.1% at a mean follow-up of 1 year (S0 condition) in children [test with signal in CI side 60% and signal normal hearing side (plugged) 31%]. The processor was used for &gt;12 h in all cases. With respect to the SSQ questionnaire, parents were more satisfied within the postoperative period than within the preoperative period. For adults, the most common etiology was idiopathic sudden sensorineural hearing loss (SNHL). Positive results in the Auditory Lateralization Test were found. With respect to the Speech Test in quiet conditions: Word recognition in noise improved from 5.7% preoperatively to 71.8% at a mean follow-up of 1 year [test with signal in CI side 68% and signal normal hearing side (plugged) 41%]. The processor was used for &gt;12 h. In the SSQ questionnaire, the post-operative results showed a beneficial effect of the CI. No adverse events were reported during the study period. No differences were found between children and adults in all tests in this study.Conclusions: Cochlear implantation in post-lingually deaf adults and children with SSD can achieve a speech perception outcome comparable with CI in conventional candidates. Improvements in spatial hearing were also observed. Careful patient selection and counseling regarding potential benefits are important to optimize outcomes.

NIDCD/VA Hearing Aid Clinical Trial and Follow-Up: Background

2007 ◽  
Vol 18 (04) ◽  
pp. 274-281 ◽  
Author(s):  
Gene W. Bratt ◽  
Mia A.L. Rosenfeld ◽  
David W. Williams
Keyword(s):  
Clinical Trial ◽  
Hearing Aids ◽  
Speech Intelligibility ◽  
Hearing Aid ◽  
Calidad De Vida ◽  
Hearing Aid Use ◽  
Life Issues ◽  
Long Term Follow Up

This report provides background regarding the Long Term Follow-Up of Patients in the NIDCD/VA Hearing Aid Clinical Trial study and serves as an introduction to the detailed reports that follow in this issue of Journal of the American Academy of Audiology. The authors investigated five- to seven-year benefit/satisfaction in participants from the original NIDCD/VA Hearing Aid Clinical Trial. The new study was designed to investigate current use of the original study hearing aids, to compare changes in selected audiological measures, and to assess possible predictors of long-term hearing aid use. The outcome measures included estimates of speech intelligibility in quiet and noise, self-reported patterns of hearing aid usage, self-reported estimates of activity limitations and quality-of-life issues, estimates of hearing aid satisfaction, and self-reported hearing aid benefit. Overall, the short-term benefits of hearing aid use observed during the original trial were noted to persist in the long term. Este reporte suministra información relacionada con el Seguimiento a Largo Plazo de los Pacientes del Estudio Clínico de Auxiliares Auditivos del NIDCD/VA, y sirve como una introducción de los reportes detallados que siguen a continuación en esta edición del Journal de la Academia Americana de Audiología. Los autores investigaron por cinco a siete años la satisfacción/beneficio en los participantes del Estudio Clínico de Auxiliares Auditivos del NIDCD/VA original. El nuevo estudio fue designado para investigar el uso actual de los auxiliares auditivos (AA) originales del estudio, para comparar cambios en las medidas audiológicas seleccionadas, y evaluar posibles elementos de predicción a largo plazo en el uso de AA. Las medidas de resultado incluyeron estimados de la inteligibilidad del lenguaje en silencio y en ruido, patrones auto-reportados de uso del AA, estimaciones auto-reportadas de limitación en la actividad y en asuntos de calidad de vida, estimaciones de satisfacción en el uso del AA y auto-reportes de beneficios con el AA. Globalmente, los beneficios a corto plazo del uso de auxiliares auditivos durante el estudio original persistieron en el largo plazo.

scholarly journals Clinical, biochemical and molecular phenotype of congenital disorders of glycosylation: long-term follow-up

2020 ◽  
Author(s):  
Anna Bogdańska ◽  
Patryk Lipiński ◽  
Paulina Szymańska-Rożek ◽  
Aleksandra Jezela-Stanek ◽  
Dariusz Rokicki ◽  
...  
Keyword(s):  
Failure To Thrive ◽  
Congenital Disorders ◽  
Type I ◽  
Congenital Disorders Of Glycosylation ◽  
Diagnostic Features ◽  
Strong Negative Correlation ◽  
Single Centre Study ◽  
Long Term Follow Up

Abstract Background: Congenital disorders of glycosylation (CDG) result from defects in the synthesis of glycans and the attachment of glycans to proteins and lipids. Our study aimed to describe the clinical, biochemical and molecular findings of CDG patients, and to present the long-term follow-up. Material and methods: A single-centre study (1995-2019 years) of patients with congenital disorders of N-glycosylation and combined N- and O-hypoglycosylation, diagnosed based on the serum transferrin (Tf) and apolipoprotein C-III (apoC-III) isoforms analysis, and confirmed molecularly, was performed. Results: Among 32 patients included into the study, 24 had type I Tf isoform profile, in 12 of them deficient PMM2 activity was detected. Three patients were diagnosed with ALG13-CDG; serum Tf isoform profile was normal in one of them, in one other was indicative for type I. Four patients had type II Tf isoform profile. The phenotypic and genotypic spectrum of 32 patients with CDG during long-term (in some cases over 20 years) observation was characterised and several measurements of serum Tf isoforms taken. Statistical analysis revealed strong negative correlation between Asialo-Tf and Tetrasialo-Tf, as well as between Disialo-Tf and Tetrasialo-Tf. Positive correlation was shown between Tetrasialo-Tf and Penasialo-Tf. Within type I CDG, no difference in % Tf isoforms was revealed between PMM2-CDG and non-PMM2-CDG patients. However, these two groups differed significantly in the such diagnostic features as: cerebellar ataxia, failure to thrive, hypothyroidism, pericardial effusion, cardiomyopathy, inverted nipples, prolonged INR. The effect of treatment with mannose in 2 patients with MPI-CDG were assesed and we found that % of Asialo-Tf, Monosialo-Tf, and Disialo-Tf was significanty lowered, whereas Tetrasialo- Tf and Pentasialo-Tf rose, coming closer or falling into the reference range. Conclusions: The novel finding was an abnormal Tf IEF pattern in two ALG13-CDG patients and normal in one ALG1-CDG patient. Clinical manifestation of presented CDG patients was similar to that reported in the literature. Mannose supplementation in MPI-CDG patients, as well as galactose supplementation in PGM-CDG patient improved patients’ clinical picture and Tf isoform profiles.

scholarly journals Nipple Reconstruction Techniques: Which is the Best Choice?

2018 ◽  
Vol 5 (1) ◽  
pp. 62-75 ◽  
Author(s):  
Nicolò Bertozzi ◽  
Francesco Simonacci ◽  
Marianna Pesce ◽  
PierLuigi Santi ◽  
Edoardo Raposio
Keyword(s):  
Donor Site ◽  
Donor Site Morbidity ◽  
Contralateral Side ◽  
Skin Thickness ◽  
Nipple Reconstruction ◽  
Areolar Complex ◽  
Long Term Follow Up ◽  
Case Basis

Nipple-Areolar Complex (NAC) reconstruction represents the final, concluding journey of breast reconstruction by being able to give to reconstructed breasts the shape of a natural breast mound. Nevertheless an enormous amount of nipple reconstruction techniques are described in literature, given the fact that most reconstructive options fail to give satisfactory outcomes in relation to the long-term nipple projection. In this review, the authors will browse most common nipple reconstruction techniques, taking into account: Indication, outcome, and side effect. Composite nipple grafts, traditional flaps, flaps with autologous graft augmentation, flaps with allograft augmentation, and flaps with alloplastic augmentation are the main strategies employed nowadays. Composite nipple grafts give the best guarantee of color-texture match with the contralateral side and show satisfactory nipple projection even at long-term follow-up. Skate, star, C-V, and arrow flap are by far the most commonly employed and the most reliable local flaps, however loss of projection of up to 70 percent are reported in literature. Alloplastic grafts were associated with the lowest rates of projection loss followed by autologous and allogenic ones. Nevertheless allogenic grafts are also associated with the highest complication rate, while autologous and allogenic ones have similar rates. Infection, seroma, and fat necrosis are the more commonly reported complications of autologous grafting along with donor site morbidity, while allogenic and alloplastic augmentation grafts may also experience the risk of overcorrection and graft exposure. Given the numerous techniques described in literature it is clear that the ideal nipple reconstruction hasn’t been found yet. Whereas it should be chosen on case to case basis depending on type of mastectomy, radiotherapy, type of reconstruction, skin thickness, tissue condition, and patients’ expectations to ensure the best cosmetic outcome.

scholarly journals Arthroscopic Wrist Debridement and Radial Styloidectomy for Advanced Scapholunate Advanced Collapse Wrist: Long-term Follow-up

Hand ◽  
2017 ◽  
Vol 13 (6) ◽  
pp. 659-665 ◽  
Author(s):  
Peter C. Noback ◽  
Mani Seetharaman ◽  
Jonathan R. Danoff ◽  
Michael Birman ◽  
Melvin P. Rosenwasser
Keyword(s):  
Return To Work ◽  
Severe Disease ◽  
Contralateral Side ◽  
Pain Patient ◽  
Dash Score ◽  
Wrist Motion ◽  
Relieve Pain ◽  
Flexion Extension ◽  
Long Term Follow Up

Background: Symptomatic stage 2 or 3 scapholunate advanced collapse (SLAC) wrist is aggressively treated with salvage procedures, such as proximal row carpectomy or partial wrist fusion with resultant pain relief but limited motion. We hypothesize that arthroscopic synovectomy, radial styloidectomy, and neurectomy will preserve wrist motion, relieve pain, and delay or avoid salvage procedures. Methods: We evaluated outcomes in 13 wrists through questionnaires and 11 of these through additional physical examination at a mean follow-up of 5.0 years. Eight wrists were stage 2 and 5 were stage 3. Data at final follow-up included mobility/strength measurements, subjective outcome scores (Disabilities of the Arm, Shoulder, and Hand [DASH] and visual analog scale [VAS] pain), patient satisfaction, and return to work statistics. Results: Patients had an average flexion-extension arc of 88.0° in the treated wrist and an average grip strength that was 95.0% of the contralateral side. No patients required revision surgery at follow-up. The 13 wrists reported an average DASH score of 16.4 and mean VAS pain score at rest and with activity of 17.9 and 31.6, respectively. All patients working prior to the procedure (n = 8) were able to immediately return to work. In all, 84.6% of patients were satisfied. Conclusions: The procedure studied may have advantages in relieving pain, while preserving wrist motion for SLAC stage 2 or 3 disease. This procedure does not preclude future salvage procedures in those patients with severe disease who prefer to maintain wrist motion for the short term. Patients experience good functional outcomes with the majority experiencing a reduction in pain with the ability to return to work.

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