Absence of interactions between social support and stressful life events in the prediction of major depression and depressive symptomatology in women

2000 ◽  
Vol 30 (4) ◽  
pp. 965-974 ◽  
Author(s):  
TRACEY D. WADE ◽  
KENNETH S. KENDLER
Keyword(s):  
Social Support ◽  
Major Depression ◽  
Life Events ◽  
Stressful Life Events ◽  
Depressive Symptomatology ◽  
Stressful Life

scholarly journals Factors related to age at depression onset: the role of SLC6A4 methylation, sex, exposure to stressful life events and personality in a sample of inpatients suffering from major depression

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Simon Sanwald ◽  
◽  
Katharina Widenhorn-Müller ◽  
Carlos Schönfeldt-Lecuona ◽  
Christian Montag ◽  
...  
Keyword(s):  
Major Depression ◽  
Life Events ◽  
Depressive Disorders ◽  
Stressful Life Events ◽  
Depressive Symptomatology ◽  
Age At Onset ◽  
Stressful Life ◽  
Entire Group ◽  
Affective Neuroscience ◽  
Depression Severity

Abstract Background An early onset of depression is associated with higher chronicity and disability, more stressful life events (SLEs), higher negative emotionality as described by the primary emotion SADNESS and more severe depressive symptomatology compared to depression onset later in life. Additionally, methylation of the serotonin transporter gene (SLC6A4) is associated with SLEs and depressive symptoms. Methods We investigated the relation of SLEs, SLC6A4 methylation in peripheral blood, the primary emotions SADNESS and SEEKING (measured by the Affective Neuroscience Personality Scales) as well as depressive symptom severity to age at depression onset in a sample of N = 146 inpatients suffering from major depression. Results Depressed women showed higher SADNESS (t (91.05) = − 3.17, p = 0.028, d = − 0.57) and higher SLC6A4 methylation (t (88.79) = − 2.95, p = 0.02, d = − 0.55) compared to men. There were associations between SLEs, primary emotions and depression severity, which partly differed between women and men. The Akaike information criterion (AIC) indicated the selection of a model including sex, SLEs, SEEKING and SADNESS for the prediction of age at depression onset. SLC6A4 methylation was not related to depression severity, age at depression onset or SLEs in the entire group, but positively related to depression severity in women. Conclusions Taken together, we provide further evidence that age at depression onset is associated with SLEs, personality and depression severity. However, we found no associations between age at onset and SLC6A4 methylation. The joint investigation of variables originating in biology, psychology and psychiatry could make an important contribution to understanding the development of depressive disorders by elucidating potential subtypes of depression.

scholarly journals Predictors of Prenatal Depression: A Cross-Sectional Study in Rural Pakistan

2021 ◽  
Vol 12 ◽  
Author(s):  
Rukhsana Khan ◽  
Ahmed Waqas ◽  
Zille Huma Mustehsan ◽  
Amna Saeed Khan ◽  
Siham Sikander ◽  
...  
Keyword(s):  
Social Support ◽  
Pregnant Women ◽  
Life Events ◽  
Stressful Life Events ◽  
Depressive Symptomatology ◽  
Perceived Social Support ◽  
Stressful Events ◽  
Prenatal Depression ◽  
Stressful Life ◽  
Personal Factors

Objective: To determine the prevalence and association of prenatal depression with socioeconomic, demographic and personal factors among pregnant women living in Kallar Syedan, Rawalpindi, Pakistan.Methods: Five hundred women in the second and third trimester of pregnancy, living in Kallar Syedan, a rural area of district Rawalpindi Pakistan, were included in the study. Depression was assessed using “Patient health questionnaire” (PHQ9) in Urdu, with a cut-off score of 10. Multi-dimensional scale of perceived social support (MSPSS) was used to assess perceived social support. Life Events and Difficulties Schedule (LEDS) were used to measure stressful life events in past 1 year. Tool to assess intimate partner violence (IPV) was based on WHO Multi Country Study on “Women's Health and Domestic Violence against Women.”Results: Prevalence of prenatal depression was found to be 27%. Number of pregnancies was significantly associated with prenatal depression (p < 0.01). Women living in a joint family and those who perceived themselves as moderately satisfied or not satisfied with their life in the next 4 years were found to be depressed (p < 0.01, OR 6.9, CI 1.77–26.73). Depressive symptomatology in women who experienced more than five stressful life events in last 1 year was three times higher (p < 0.001, OR 3.2, CI 1.68–5.98) than in women with 1–2 stressful events. Women who were supported by their significant others or their family members had 0.9 times (p < 0.01, OR 0.9, CI 0.85–0.96) less chance of getting depressed. Pregnant women who were psychologically abused by their partners were 1.5 times more depressed (p < 0.05 CI 1.12–2.51). Odds of having depression was also high in women who had less mean score of MSSI (p < 0.05, OR 1.1, CI 1.01–1.09). Women who had suitable accommodation had 0.5 times less chance of having depression than others (p < 0.05, OR 0.5, CI 0.27–0.92).Conclusion: Over a quarter of the women in the study population reported prenatal depression, which were predicted predominantly by psychosocial variables.

The Impact of Stressful Life Events and Social Support on Drinking among Older Adults: A General Population Survey

1992 ◽  
Vol 35 (2) ◽  
pp. 99-123 ◽  
Author(s):  
Karen M. Jennison
Keyword(s):  
Social Support ◽  
Older Adults ◽  
Life Events ◽  
Stressful Life Events ◽  
Prolonged Exposure ◽  
Drinking Behavior ◽  
National Sample ◽  
Stressful Life ◽  
Stress Buffering ◽  
The Impact

This article is an analysis of stressful life events, the buffering hypothesis, and alcohol use in a national sample of 1,418 respondents 60 years of age and over. The results indicate that older adults who experience stressful losses are significantly more likely to drink excessively than those who have not experienced such losses or who have experienced them to a lesser extent. Increased drinking among older adults may therefore be a reaction to life circumstances in which alcohol represents an attempt to cope with traumatic loss, personal as well as within the kinship network. Supportive resources of spouse, family, friends, and church appear to have a stress-buffering effects that reduces the excessive-drinking response to life crisis. Data suggest, however, that older persons are vulnerable to the magnitude of losses experienced as they grow older and lose more of their family, friends, and peers. These stressors appear to seriously impact their drinking behavior and are not effectively buffered. Respondents report that drinking may increase during periods of prolonged exposure to emotionally depleting life change and loss, when supportive needs may exceed the capacities of personal and social support resources.

The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR in major depression

2013 ◽  
Vol 47 (8) ◽  
pp. 1032-1035 ◽  
Author(s):  
Robert A. Power ◽  
Lucy Lecky-Thompson ◽  
Helen L. Fisher ◽  
Sarah Cohen-Woods ◽  
Georgina M. Hosang ◽  
...  
Keyword(s):  
Major Depression ◽  
Child Maltreatment ◽  
Life Events ◽  
Stressful Life Events ◽  
Stressful Life

Stressful Life Events Interacting With Cognitive/Personality Styles to Predict Late-Onset Major Depression

2002 ◽  
Vol 10 (3) ◽  
pp. 297-304 ◽  
Author(s):  
Carolyn M. Mazure ◽  
Paul K. Maciejewski ◽  
Selby C. Jacobs ◽  
Martha L. Bruce
Keyword(s):  
Major Depression ◽  
Life Events ◽  
Stressful Life Events ◽  
Late Onset ◽  
Stressful Life ◽  
Personality Styles

scholarly journals Assessment of Gender Differences in Depression- A Cross-Sectional study

2021 ◽  
pp. 28-33
Author(s):  
Tushar Agravat
Keyword(s):  
Gender Differences ◽  
Statistical Analysis ◽  
Major Depression ◽  
Life Events ◽  
Stressful Life Events ◽  
Nuclear Family ◽  
Demographic Characteristics ◽  
Stressful Life ◽  
Significant Difference ◽  
One Year

Background and Aim: Major depression in both women and men is a debilitating disorder that disrupts relationship and daily lives and affects nearly 10% of general populations. The aims and objectives of this study were to determine the gender differences in major depression with respect to following: Demographic characteristics, Clinical manifestations, Stressful life events, Risk factors. Materials and Methods: Total of 100 patients was included in the study. All the included patients meet the criteria for DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) diagnosis of major depression. The included patients were interviewed at the department of Psychiatry, B. J. Medical College & civil hospital Ahmedabad. Based on the Life Events Scale by Holmes and Rahe (1967), its Indian adaptation PSLE (Presumptive stressful life events scale) was done by Gurmeet Singh (1983). The statistical analysis was done by using SPSS IX version. Results: Their ages range from 18 to 70 years. Most of the patients were married, were from urban background, and nuclear family. On Hamilton Depression rating scale when the statistical analysis was done, there was no significant difference between males and females. Men had higher mean life events score than women but this was not statistically significant. In female, there was significant positive correlation between number of life events in one year and severity of depression as well as impact score during one year prior to onset of depression and Hamilton rating scores. Conclusion: Male and female major depression patients did not differ as regards demographic characteristics, except that most women were homemakers and men were employed. Number of stressful life events experienced during 1 year prior to onset of MDD was similar. Early insomnia, middle insomnia and somatic symptoms general were more severely present in female patients.

scholarly journals Effect of OPRM1 and stressful life events on symptoms of major depression in African American adolescents

2014 ◽  
Vol 162 ◽  
pp. 12-19 ◽  
Author(s):  
Gregory Swann ◽  
Gayle R. Byck ◽  
Danielle M. Dick ◽  
Fazil Aliev ◽  
Shawn J. Latendresse ◽  
...  
Keyword(s):  
African American ◽  
Major Depression ◽  
Life Events ◽  
Stressful Life Events ◽  
African American Adolescents ◽  
Stressful Life
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