scholarly journals Electroclinical Analysis of Postictal Noserubbing

2000 ◽  
Vol 27 (2) ◽  
pp. 131-136 ◽  
Author(s):  
Richard Wennberg
Keyword(s):  
Temporal Lobe ◽  
Seizure Onset ◽  
Scalp Eeg ◽  
Autonomic Activation ◽  
Ictal Activity ◽  
Primary Generalized Epilepsy ◽  
Generalized Epilepsy ◽  
Temporal Lobe Seizure ◽  
Intracranial Electrodes ◽  
Video Eeg

ABSTRACT:Background:Postictal noserubbing (PIN) has been identified as a good, albeit imperfect, lateralizing and localizing sign in human partial epilepsy, possibly related to ictal autonomic activation.Methods:PIN was studied prospectively in a group of consecutive patients admitted for video-EEG monitoring, with the laterality of noserubbing correlated with electrographic sites of seizure onset, intra- and interhemispheric spread, and sites of seizure termination.Results:PIN was significantly more frequent in temporal than extratemporal epilepsy (p<0.001; 23/41 (56%) patients and 41/197 (21%) seizures in temporal lobe epilepsy compared with 4/34 (12%) patients and 12/167 (7%) seizures in extratemporal epilepsy). The hand used to rub the nose was ipsilateral to the side of seizure onset in 83% of both temporal and extratemporal seizures. Seizures with contralateral PIN correlated with spread to the contralateral temporal lobe on scalp EEG (p<0.04). All extratemporal seizures with PIN showed spread to temporal lobe structures. One patient investigated with intracranial electrodes showed PIN only when ictal activity spread to involve the amygdala: seizures confined to the hippocampus were not associated with PIN. PIN was not observed in 63 nonepileptic events in 17 patients. Unexpectedly, one patient with primary generalized epilepsy showed typical PIN after 1/3 recorded absence seizures.Conclusions:This study confirms PIN as a good indicator of ipsilateral temporal lobe seizure onset. Instances of false lateralization and localization appear to reflect seizure spread to contralateral or ipsilateral temporal lobe structures, respectively. Involvement of the amygdala appears to be of prime importance for induction of PIN.

Ictal Blinking: Reappraisal of the Lateralization and Localization Value in Focal Seizures

2022 ◽  
pp. 155005942110708
Author(s):  
Ayse Nur Ozdag Acarli ◽  
Ayse Deniz Elmali ◽  
Nermin Gorkem Sirin ◽  
Betul Baykan ◽  
Nerses Bebek
Keyword(s):  
The Other ◽  
Eeg Monitoring ◽  
Seizure Onset ◽  
Future Studies ◽  
Focal Seizures ◽  
Scalp Eeg ◽  
Ictal Activity ◽  
Generalized Epilepsy ◽  
Video Eeg ◽  
Sign Method

Introduction. Although ictal blinking is significantly more frequent in generalized epilepsy, it has been reported as a rare but useful lateralizing sign in focal seizures when it is not associated with facial clonic twitching. This study aimed to raise awareness of eye blinking as a semiological lateralizing sign. Method. Our database over an 11-year period reviewed retrospectively to assess patients who had ictal blinking associated with focal seizures. Results. Among 632 patients, 14 (2.2%), who had 3 to 13 (7 ± 3) seizures during video-EEG monitoring, were included. Twenty-five percent of all 92 seizures displayed ictal blinking and each patient had one to five seizures with ictal blinking. Ictal blinking was unilateral in 17%, asymmetrical in 22% and symmetrical in 61%. The blinking appeared with a mean latency of 6.3 s (range 0-39) after the clinical seizure-onset, localized most often to fronto-temporal, then in frontal or occipital regions. Blinking was ipsilateral to ictal scalp EEG lateralization side in 83% (5/6) of the patients with unilateral/asymmetrical blinking. The exact lateralization and localization of ictal activity could not have been determined via EEG in most of the patients with symmetrical blinking, remarkably. Conclusions. Unilateral/asymmetrical blinking is one of the early components of the seizures and appears as a useful lateralizing sign, often associated with fronto-temporal seizure-onset. Symmetrical blinking, on the other hand, did not seem to be valuable in lateralization and localization of focal seizures. Future studies using invasive recordings and periocular electrodes are needed to evaluate the value of blinking in lateralization and localization.

scholarly journals False lateralization of seizure onset by scalp EEG in neocortical temporal lobe epilepsy

Seizure ◽  
2011 ◽  
Vol 20 (6) ◽  
pp. 494-499 ◽  
Author(s):  
Bola Adamolekun ◽  
Pegah Afra ◽  
F.A. Boop
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Seizure Onset ◽  
Scalp Eeg

scholarly journals False Lateralization of Seizure Onset by Scalp EEG in Non-lesional Temporal Lobe Epilepsy : A Surgical Case Report

2014 ◽  
Vol 23 (9) ◽  
pp. 744-749
Author(s):  
Masaki Iwasaki ◽  
Kazutaka Jin ◽  
Kazuhiro Kato ◽  
Shin-ichiro Osawa ◽  
Yoshiteru Shimoda ◽  
...  
Keyword(s):  
Case Report ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Seizure Onset ◽  
Surgical Case ◽  
Scalp Eeg

scholarly journals Three-dimensional hippocampal atrophy maps distinguish two common temporal lobe seizure-onset patterns

Epilepsia ◽  
2009 ◽  
Vol 50 (6) ◽  
pp. 1361-1370 ◽  
Author(s):  
Jennifer A. Ogren ◽  
Anatol Bragin ◽  
Charles L. Wilson ◽  
Gil D. Hoftman ◽  
Jack J. Lin ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Three Dimensional ◽  
Hippocampal Atrophy ◽  
Seizure Onset ◽  
Temporal Lobe Seizure

scholarly journals Functional and Anatomic Correlates of Two Frequently Observed Temporal Lobe Seizure-Onset Patterns

2000 ◽  
Vol 7 (1-2) ◽  
pp. 49-63 ◽  
Author(s):  
Ana Luisa Velascol ◽  
Charles L. Wilson ◽  
Thomas L. Babb ◽  
Jerome Engel Jr
Keyword(s):  
Temporal Lobe ◽  
Low Voltage ◽  
Low Frequency ◽  
Neuronal Loss ◽  
High Amplitude ◽  
Seizure Onset ◽  
Depth Electrodes ◽  
Cell Counts ◽  
Number Of Patients ◽  
Temporal Lobe Seizure

Intracranial depth electrode EEG records of 478 seizures, recorded in 68 patients undergoing diagnostic monitoring with depth electrodes, were evaluated to investigate the correlates of electrographic onset patterns in patients with temporal lobe seizures. The seizure onsets in 78% of these patients were identified as either hypersynchronous onsets, beginning with low-frequency, high-amplitude spikes, or low-voltage fast (LVF) onsets, increasing in amplitude as the seizure progressed. The number of patients (35) having hypersynchronous seizure onsets was nearly twice that of patients (18) having LVF onsets. Three major differences were seen among patients with the two seizure-onset patterns. When compared with patients having LVF onsets, patients with hypersynchronous seizure onsets had a significantly greater probability of having (1) focal rather than regional seizure onsets (p<0.01), (2) seizures spreading more slowly to the contralateral mesial temporal lobe (p<0.003), and (3) cell counts in resected hippocampal tissue showing greater neuronal loss (p<0.001). The results provide evidence that the most frequent electrographic abnormality associated with mesial temporal seizures is local hypersynchrony, a condition associated with major neuronal-loss in the hippocampus. The results also indicate that LVF seizure onsets more frequently represent widely distributed discharges, which interact with and spread more rapidly to surrounding neocortical areas.

Do dichotic word listening asymmetries predict side of temporal lobe seizure onset?

1994 ◽  
Vol 19 (2) ◽  
pp. 153-160 ◽  
Author(s):  
Gregory P. Lee ◽  
David W. Loring ◽  
Nils R. Varney ◽  
Richard J. Roberts ◽  
Jason R. Newell ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Seizure Onset ◽  
Temporal Lobe Seizure

The Epileptic Pre-Aura

2002 ◽  
Vol 33 (2) ◽  
pp. 58-61 ◽  
Author(s):  
E. Niedermeyer
Keyword(s):  
Good Reason ◽  
Frontal Region ◽  
Vascular Changes ◽  
Seizure Onset ◽  
Quantified Eeg ◽  
Primary Generalized Epilepsy ◽  
Generalized Epilepsy

The term “pre-aura” is used for the designation of earliest pre-ictal manifestations that escape detection by conventional EEG and both objective and subjective behavioral signs. Fairly recent reports have indicated earliest pre-ictal vascular changes (perifocal ischemia and hyperemia) and also changes found in various methods of quantified EEG. These changes may precede the seizure onset (in conventional terms) by 1 to 20 minutes. There is good reason to assume that pre-auras are limited to focal epilepsies and do not occur in the various subforms of primary generalized epilepsy. The electrodecremental type of seizure onset, mostly found in the frontal region, could also denote a pre-aura in the earliest decremental phase. The very earliest pre-aura phenomena are most likely to be neuronal rather than vascular. Further proof could come with the use of ultrafast EEG frequency recordings.

Hyposexuality and epilepsy: a community survey of hormonal and behavioural changes in male epileptics

1989 ◽  
Vol 19 (4) ◽  
pp. 937-943 ◽  
Author(s):  
B. K. Toone ◽  
J. Edeh ◽  
M. N. Nanjee ◽  
M. Wheeler
Keyword(s):  
Sexual Activity ◽  
Temporal Lobe ◽  
Free Testosterone ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Healthy Population ◽  
Male Patients ◽  
Primary Generalized Epilepsy ◽  
Generalized Epilepsy ◽  
Hormonal Analysis

SYNOPSISA survey of five group practices in South London identified 60 male patients currently undergoing treatment for epilepsy. Fifty-four agreed to participate in a detailed enquiry into aspects of their sexual activity and behaviour. Anterior pituitary and sex-hormone levels were measured. The epileptic patients were characterized by low levels of sexual activity and interest. Temporal-lobe and non-temporal-lobe epileptics were indistinguishable in these respects, but when the latter group was further subdivided into primary generalized epilepsy and focal non-temporal lobe epilepsy, the focal groups (both temporal lobe and non-temporal lobe) were more impaired. Hormonal analysis confirmed earlier hospital-clinic-based reports. In the epilepsy group, plasma free testosterone and percentage free testosterone values were decreased, sex hormone binding globulin, luteinizing hormone (LH) and follicle stimulating hormone (FSH) were increased compared to values in a normal healthy population. As association between the behavioural and hormonal indices of hyposexuality was shown, particularly for LH, but this was less apparent than in previous work.

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