scholarly journals The evolution and distribution of phage ST160 within Salmonella enterica serotype Typhimurium

2010 ◽  
Vol 139 (8) ◽  
pp. 1262-1271 ◽  
Author(s):  
M. PRICE-CARTER ◽  
P. ROY-CHOWDHURY ◽  
C. E. POPE ◽  
S. PAINE ◽  
G. W. DE LISLE ◽  
...  
Keyword(s):  
New Zealand ◽  
Salmonella Enterica ◽  
Recent Past ◽  
Major Threat ◽  
Serovar Typhimurium ◽  
The Usa ◽  
Clonal Spread ◽  
Important Disease

SUMMARYSalmonellosis is an internationally important disease of mammals and birds. Unique epidemics in New Zealand in the recent past include two Salmonella serovars: Salmonella enterica subsp. enterica serovar Typhimurium definitive type (DT) 160 (S. Typhimurium DT160) and S. Brandenburg. Although not a major threat internationally, in New Zealand S. Typhimurium DT160 has been the most common serovar isolated from humans, and continues to cause significant losses in wildlife. We have identified DNA differences between the first New Zealand isolate of S. Typhimurium DT160 and the genome-sequenced strain, S. Typhimurium LT2. All the differences could be accounted for in one cryptic phage ST64B, and one novel P22-like phage, ST160. The majority of the ST160 genome is almost identical to phage SE1 but has two regions not found in SE1 which are identical to the P22-like phage ST64T, suggesting that ST160 evolved from SE1 via two recombination events with ST64T. All of the New Zealand isolates of DT160 were identical indicating the clonal spread of this particular Salmonella. Some overseas isolates of S. Typhimurium DT160 differed from the New Zealand strain and contained SE1 phage rather than ST160. ST160 was also identified in New Zealand isolates of S. Typhimurium DT74 and S. Typhimurium RDNC-April06 and in S. Typhimurium DT160 isolates from the USA. The emergence of S. Typhimurium DT160 as a significant pathogen in New Zealand is postulated to have occurred due to the sensitivity of the Salmonella strains to the ST160 phage when S. Typhimurium DT160 first arrived.

scholarly journals Antimicrobial and Antivirulence Impacts of Phenolics on Salmonella Enterica Serovar Typhimurium

Antibiotics ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 668
Author(s):  
Zabdiel Alvarado-Martinez ◽  
Paulina Bravo ◽  
Nana-Frekua Kennedy ◽  
Mayur Krishna ◽  
Syed Hussain ◽  
...  
Keyword(s):  
Salmonella Enterica ◽  
Salmonella Enterica Serovar Typhimurium ◽  
Infectious Agent ◽  
Resistance Pattern ◽  
Fluorescent Intensity ◽  
Antimicrobial Potential ◽  
Serovar Typhimurium ◽  
Morphological Defects ◽  
The Usa ◽  
Alternative Antimicrobials

Salmonella enterica serovar Typhimurium (ST) remains a major infectious agent in the USA, with an increasing antibiotic resistance pattern, which requires the development of novel antimicrobials capable of controlling ST. Polyphenolic compounds found in plant extracts are strong candidates as alternative antimicrobials, particularly phenolic acids such as gallic acid (GA), protocatechuic acid (PA) and vanillic acid (VA). This study evaluates the effectiveness of these compounds in inhibiting ST growth while determining changes to the outer membrane through fluorescent dye uptake and scanning electron microscopy (SEM), in addition to measuring alterations to virulence genes with qRT-PCR. Results showed antimicrobial potential for all compounds, significantly inhibiting the detectable growth of ST. Fluorescent spectrophotometry and microscopy detected an increase in relative fluorescent intensity (RFI) and red-colored bacteria over time, suggesting membrane permeabilization. SEM revealed severe morphological defects at the polar ends of bacteria treated with GA and PA, while VA-treated bacteria were found to be mid-division. Relative gene expression showed significant downregulation in master regulator hilA and invH after GA and PA treatments, while fliC was upregulated in VA. Results suggest that GA, PA and VA have antimicrobial potential that warrants further research into their mechanism of action and the interactions that lead to ST death.

Salmonella entericaserotypes and antibiotic susceptibility in New Zealand, 2002–2007

2009 ◽  
Vol 138 (3) ◽  
pp. 322-329 ◽  
Author(s):  
E. I. BROUGHTON ◽  
H. M. HEFFERNAN ◽  
C. L. COLES
Keyword(s):  
New Zealand ◽  
Salmonella Enterica ◽  
Antibiotic Susceptibility ◽  
Serovar Typhimurium ◽  
Common Serotypes ◽  
Almost All ◽  
Changes Over Time ◽  
Over Time

SUMMARYWe analysed the serotypes and antibiotic susceptibility of 1560 human and 1505 non-humanSalmonellaisolated in New Zealand (NZ) between 2002 and 2007. The most common serotypes in humans wereSalmonella entericaserovar Typhimurium,S. Enteritidis,S. Brandenburg andS. Infantis. Over the 6-year period human cases due toS. Agona andS. Enteritidis increased and cases due toS. Typhimurium decreased. The most common serotypes from non-human sources wereS. Typhimurium,S. Brandenberg,S. Hindmarsh andS. Infantis, and there were no significant changes over time. More isolates were non-susceptible to streptomycin than to any other antibiotic. Almost all isolates were susceptible to ciprofloxacin and gentamicin. There were significant trends of increasing non-susceptibility to streptomycin and sulfonamides in isolates from human and non-human sources, while ampicillin, tetracycline and multidrug non-susceptibility also increased in human isolates. Despite these increases, rates of antibiotic non-susceptibility inSalmonellain NZ are still lower than in many international settings.

scholarly journals Genomic Analysis of Salmonella enterica Serovar Typhimurium DT160 Associated with a 14-Year Outbreak, New Zealand, 1998–2012

2017 ◽  
Vol 23 (6) ◽  
pp. 906-913 ◽  
Author(s):  
Samuel J. Bloomfield ◽  
Jackie Benschop ◽  
Patrick J. Biggs ◽  
Jonathan C. Marshall ◽  
David T.S. Hayman ◽  
...  
Keyword(s):  
New Zealand ◽  
Salmonella Enterica ◽  
Salmonella Enterica Serovar Typhimurium ◽  
Genomic Analysis ◽  
Serovar Typhimurium

An Immigrant Filmmaker Substitutes an Alternative Vision of Adolescence: The Scarecrow (Sam Pillsbury, 1982)

2018 ◽  
Author(s):  
Alistair Fox
Keyword(s):  
New Zealand ◽  
Cinematic Adaptation ◽  
Alternative Vision ◽  
The Face ◽  
The Usa ◽  
Genre Film

By comparing Sam Pillsbury’s cinematic adaptation of Ronald Hugh Morrieson’s The Scarecrow (1963) with the original, this chapter shows how the filmmaker, who was raised in the USA and immigrated to New Zealand in his teens, empties the source novel of the moral ambiguities and transgressive elements that had made the original a genuinely New Zealand work, in so far as it reflected puritan guilt over transgressive impulses in the face of repression, and thus turned the story into a genre film that that is much more anodyne in its vision.

The Influence of the Infomercial in New Zealand

2019 ◽  
pp. 67-80
Author(s):  
Rosser Johnson
Keyword(s):  
New Zealand ◽  
Primary Sources ◽  
Cultural Impact ◽  
Cultural Importance ◽  
The Usa ◽  
The 1950S ◽  
As If

New Zealand television networks introduced infomercials (30 minute advertisements designed to appear as if they are programmes) in late 1993. Although infomercials date from the 1950s in the USA, they were unknown in this country and quickly came to be seen as a peculiarly “intense” form of hyper-commercial broadcasting. This article aims to sketch out the cultural importance of the infomercial by analysing historical published primary sources (from the specialist and general press) as they reflect the views and opinions that resulted from the introduction of the infomercial. Specifically, it outlines the three main areas where that cultural importance was located. It concludes by analysing the significance of the cultural impact of the infomercial, both within broadcasting and within wider society.

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