Increased risk of tuberculosis in patients with end-stage renal disease: a population-based cohort study in Taiwan, a country of high incidence of end-stage renal disease

2013 ◽  
Vol 142 (1) ◽  
pp. 191-199 ◽  
Author(s):  
H. Y. HU ◽  
C. Y. WU ◽  
N. HUANG ◽  
Y. J. CHOU ◽  
Y. C. CHANG ◽  
...  
Keyword(s):  
Cohort Study ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Proportional Hazards ◽  
Population Based ◽  
Cox Proportional Hazards ◽  
Chronic Obstructive ◽  
Increased Risk ◽  
Stage Renal Disease ◽  
End Stage

SUMMARYThis nationwide population-based cohort study investigated the risk of tuberculosis (TB) in patients with end-stage renal disease (ESRD) and receiving dialysis. The evaluations included 4131 incident ESRD patients receiving dialysis and 16 524 age- and gender-matched controls, recruited between 1998 and 2009. We used Cox proportional hazards regression analysis to measure the association between TB and ESRD. Compared to the controls, the ESRD cohort had a significantly higher risk of TB within 1 year [incident rate ratio (IRR) 4·13], and 1–2 years (IRR 2·12), of occurrence of ESRD. The Cox proportional hazards model revealed that ESRD [hazard ratio (HR) 2·40], age >65 years (HR 2·41), male sex (HR 1·94), diabetes mellitus (HR 1·36), silicosis (HR 7·70) and chronic obstructive pulmonary disease (HR 1·61) are independent risk factors for TB. Patients with ESRD are associated with an increased risk of TB, and should thus be monitored more carefully for TB, especially within 2 years of onset of ESRD.

scholarly journals Erythropoietin Use and the Risk of Stroke in Patients on Hemodialysis: A Retrospective Cohort Study in Taiwan

2021 ◽  
Author(s):  
Peir‐Haur Hung ◽  
Chih‐Ching Yeh ◽  
Chih‐Yen Hsiao ◽  
Chih‐Hsin Muo ◽  
Kuan‐Yu Hung ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Proportional Hazards Regression ◽  
Defined Daily Doses ◽  
Hazard Ratios ◽  
Increased Risk ◽  
Stage Renal Disease ◽  
End Stage

Background Targeting higher hemoglobin levels with erythropoietin to treat anemia in patients with chronic kidney disease is associated with increased cardiovascular risk, including that of stroke. The risks of the subtypes of stroke, ischemic, hemorrhagic, and unspecified, following the administration of erythropoietin in patients with end‐stage renal disease receiving hemodialysis remain unclear. Methods and results Overall, 12 948 adult patients with end‐stage renal disease treated during 1999 to 2010 who had undergone hemodialysis were included. The study end points were the incidences of stroke and its subtypes. We used Cox proportional hazards regression models to estimate hazard ratios (HRs) of stroke and its subtypes in erythropoietin recipients compared with nonrecipients. Patients in the erythropoietin cohort did not have an increased risk of stroke compared with those in the nonerythropoietin cohort (adjusted HR, 1.03; 95% CI, 0.92–1.15). Compared with patients in the nonerythropoietin cohort, the risks of ischemic, hemorrhagic, or unspecified stroke were not higher in patients in the erythropoietin cohort (adjusted HRs, 1.08 [95% CI, 0.93–1.26], 0.96 [95% CI, 0.78–1.18], and 1.03 [95% CI, 0.80–1.32], respectively). Increased risks of stroke and its subtypes were not observed with even large annual defined daily doses of erythropoietin (>201). Conclusions Erythropoietin in patients receiving hemodialysis is not associated with increased risk of stroke or any of its subtypes.

scholarly journals Comparison of Risk for End-Stage Renal Disease Between Physicians and the General Population: A Nationwide Population-Based Cohort Study

2019 ◽  
Vol 16 (12) ◽  
pp. 2211
Author(s):  
Chin-Kai Yen ◽  
Tian-Hoe Tan ◽  
I-Jung Feng ◽  
Chung-Han Ho ◽  
Chien-Chin Hsu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Peritoneal Dialysis ◽  
Renal Transplantation ◽  
General Population ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Population Based ◽  
Easy Access ◽  
Stage Renal Disease ◽  
End Stage

Physicians experience high stress and have much responsibility during a night shift, which contributes to increased sympathetic activity, the risk factor for renal disease. The risk for end-stage renal disease (ESRD) in physicians is still unclear. Therefore, we conducted a nationwide population-based cohort study to clarify this issue. Using Taiwan’s National Health Insurance Research Database, we identified 30,268 physicians and 60,536 individuals from the general population matched with a ratio of 1:2 by age and sex. All participants who had ESRD before 2006 and residents were excluded. ESRD risk between physicians and the general population and among physician subgroups was compared by following up their medical histories until 2012. We also compared the treatments between both cohorts with ESRD. Physicians had a lower ESRD risk than the general population (adjusted odds ratio (AOR): 0.5; 95% confidence interval (CI): 0.4–0.7), particularly in the middle-age subgroup (35–64 years) (AOR: 0.4; 95% CI: 0.3–0.7); however, there was no difference in the older age subgroup (≥65 years) (AOR: 1.0; 95% CI: 0.6–1.7). More physicians received peritoneal dialysis (63.0% vs. 11.1%) and renal transplantation (5.6% vs. 1.7%) than the general population after being diagnosed with ESRD. Compared with the general population, physicians had a lower ESRD risk and higher treatment selection for peritoneal dialysis and renal transplantation after being diagnosed with ESRD. Better medical knowledge, a greater awareness of diseases and their risk factors, more rigorous implementation of preventive measures, and easy access to medical care may play a role in this aspect. Further studies are warranted for elucidating the associated mechanisms.

Risk of idiopathic peripheral neuropathy in end‐stage renal disease: A population‐based cohort study

2020 ◽  
Vol 75 (1) ◽  
Author(s):  
Shih‐Yi Lin ◽  
Cheng‐Li Lin ◽  
Wu‐Huei Hsu ◽  
Cheng‐Chieh Lin ◽  
Sui‐Foon Lo ◽  
...  
Keyword(s):  
Cohort Study ◽  
Peripheral Neuropathy ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Population Based ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Risk of acute coronary syndrome after parathyroidectomy in patients with end-stage renal disease: A population-based cohort study in Taiwan

Nephrology ◽  
2018 ◽  
Vol 23 (2) ◽  
pp. 139-147 ◽  
Author(s):  
Tsung Liang Ma ◽  
Rei Yeuh Chang ◽  
Hsuan Ju Chen ◽  
Chun Yi Liu ◽  
Chih Cheng Hsu ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Cohort Study ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Population Based ◽  
Coronary Syndrome ◽  
Stage Renal Disease ◽  
End Stage
Sign in / Sign up

Export Citation Format

Share Document