scholarly journals Chlamydia pneumoniae is a risk factor for coronary heart disease in symptom-free elderly men, but Helicobacter pylori and cytomegalovirus are not

1998 ◽  
Vol 120 (1) ◽  
pp. 93-99 ◽  
Author(s):  
J. M. OSSEWAARDE ◽  
E. J. M. FESKENS ◽  
A. DE VRIES ◽  
C. E. VALLINGA ◽  
D. KROMHOUT
Keyword(s):  
Coronary Heart Disease ◽  
Helicobacter Pylori ◽  
Heart Disease ◽  
Coronary Heart Disease Risk ◽  
Chlamydia Pneumoniae ◽  
Disease Risk ◽  
Coronary Event ◽  
Elderly Men ◽  
H Pylori ◽  
Heart Disease Risk

To test the hypothesis that chronic infection with Chlamydia pneumoniae, Helicobacter pylori or cytomegalovirus is associated with coronary heart disease risk in elderly men, a nested case-control study in a cohort investigated in 1985 and 1990 in the town of Zutphen, The Netherlands, was designed. Fifty-four cases with a first diagnosed coronary event between 1985 and 1990, and 108 age-matched control subjects free of coronary heart disease during follow up were included in the study. The overall prevalence of antibodies to cytomegalovirus was 74·7%, to H. pylori 75·9% and to C. pneumoniae 84·0%. A high level of antibodies to C. pneumoniae was associated with an increased coronary heart disease risk (OR=2·76; 95% CI=1·31–5·81). This association was stronger in cases developing both myocardial infarction and angina pectoris, than in cases developing only one of these. This association was independent of potential confounders. Antibodies to cytomegalovirus or H. pylori were not associated with coronary heart disease risk. These results support the hypothesis of a role of chronic C. pneumoniae infections in the immunopathogenesis of atherosclerosis.

Non-invasively measured structural and functional arterial characteristics and coronary heart disease risk in middle aged and elderly men

2006 ◽  
Vol 187 (1) ◽  
pp. 110-115 ◽  
Author(s):  
Marijke J.C.A. van Trijp ◽  
Willem J.W. Bos ◽  
Yvonne T. van der Schouw ◽  
Majon Muller ◽  
Diederick E. Grobbee ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Heart Disease Risk ◽  
Disease Risk ◽  
Middle Aged ◽  
Elderly Men ◽  
Heart Disease Risk

TRACE METALS AND CORONARY HEART DISEASE RISK INDICATORS IN 152 ELDERLY MEN (THE ZUTPHEN STUDY)

1985 ◽  
Vol 122 (3) ◽  
pp. 378-385 ◽  
Author(s):  
D. KROMHOUT ◽  
A. A. E. WIBOWO ◽  
R. F. M. HERBER ◽  
L. M. DALDERUP ◽  
H. HEERDINK ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Trace Metals ◽  
Coronary Heart Disease Risk ◽  
Disease Risk ◽  
Risk Indicators ◽  
Elderly Men ◽  
Heart Disease Risk

The Joy of Statistics

2019 ◽  
Author(s):  
Steve Selvin
Keyword(s):  
Coronary Heart Disease ◽  
Short Stories ◽  
Heart Disease ◽  
Infant Mortality ◽  
Statistical Methods ◽  
Ethnic Differences ◽  
Coronary Heart Disease Risk ◽  
Disease Risk ◽  
Mortality Rates ◽  
Heart Disease Risk

The Joy of Statistics consists of a series of 42 “short stories,” each illustrating how elementary statistical methods are applied to data to produce insight and solutions to the questions data are collected to answer. The text contains brief histories of the evolution of statistical methods and a number of brief biographies of the most famous statisticians of the 20th century. Also throughout are a few statistical jokes, puzzles, and traditional stories. The level of the Joy of Statistics is elementary and explores a variety of statistical applications using graphs and plots, along with detailed and intuitive descriptions and occasionally using a bit of 10th grade mathematics. Examples of a few of the topics are gambling games such as roulette, blackjack, and lotteries as well as more serious subjects such as comparison of black/white infant mortality rates, coronary heart disease risk, and ethnic differences in Hodgkin’s disease. The statistical description of these methods and topics are accompanied by easy to understand explanations labeled “how it works.”

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