Identification and expression analysis of Dazl homologue in Cynops cyanurus
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Summary The Dazl (deleted in azoospermia-like) gene encodes an RNA-binding protein containing an RNA recognition motif (RRM) and a DAZ motif. Dazl is essential for gametogenesis in vertebrates. In this study, we report the cloning of Dazl cDNA from Cynops cyanurus. Ccdazl mRNA showed a germline-specific expression pattern as expected. Ccdazl expression gradually decreased during oogenesis, suggesting that it may be involved in oocyte development. Phylogenetic analysis revealed that the Ccdazl protein shares conserved motifs/domains with Dazl proteins from other species. Cloning of Ccdazl provides a new tool to carry out comparative studies of germ cell development in amphibians.
2021 ◽
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2009 ◽
Vol 284
(50)
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pp. 35015-35028
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2013 ◽
Vol 69
(10)
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pp. 1107-1109
Keyword(s):
1997 ◽
Vol 110
(15)
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pp. 1741-1750
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Keyword(s):
1993 ◽
Vol 13
(6)
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pp. 3494-3504
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