Extensive coronary and systemic arterial aneurysm development in severe refractory Kawasaki disease

2016 ◽  
Vol 27 (2) ◽  
pp. 375-376 ◽  
Author(s):  
Niall Johnston ◽  
David Coleman ◽  
Colin J. McMahon

AbstractWe describe the case of an 8-week-old infant with late presentation of severe refractory atypical Kawasaki disease. In addition to developing giant coronary arterial aneurysms and coronary thrombosis, she formed extensive bilateral arterial aneurysms throughout her systemic circulation.

PEDIATRICS ◽  
1981 ◽  
Vol 68 (6) ◽  
pp. 885-888 ◽  
Author(s):  
Charles E. Canter ◽  
Richard J. Bower ◽  
Arnold W. Strauss

Kawasaki disease (mucocutaneous lymph node syndrome), initially described in Japan, is now being seen with increasing frequency in the United States.1 The diagnosis is based on the typical constellation of signs and symptoms.1,2 Mortality is 1% to 2%, and significant morbidity results from aneurysmal formation in midsize arteries, especially the coronary arteries, which may result in rupture or myocardial infarction. We report an unusual case of Kawasaki disease. The initial febrile illness was an atypical presentation. A large abdominal aortic aneurysm developed, which subsequently was resected. Seven months after the febrile illness an asymptomatic myocardial infarction secondary to bilateral coronary arterial aneurysms was documented.


2009 ◽  
Vol 19 (4) ◽  
pp. 395-396
Author(s):  
Rebeca Sarrat Torres ◽  
Pedro Betrián Blasco ◽  
María Dolores García de la Calzada

2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Rahul D. Bhiwgade ◽  
M. C. Nischitha ◽  
Bhushan Shahare ◽  
Shobhna Bitey

Abstract Background Adolescents with coronavirus disease 2019 (COVID-19) associated multisystem inflammatory syndrome (MIS) can present with shock and myocardial injury and mimic Kawasaki disease. Case presentation We describe 4 previously well adolescents (age 13–14 years), presenting with clinical features of MIS in children (MIS-C). All patients had nearly similar clinical presentation. Hematological investigations revealed elevated inflammatory markers, anemia, thrombocytopenia, and decreased neutrophil:lymphocyte ratio. All patients were negative on real-time polymerase chain reaction against severe acute respiratory syndrome coronavirus 2, but had elevated immunoglobulin G titers. Two patients had atypical Kawasaki disease. Three patients had severe disease with hypotensive shock and required intensive care with fluids and inotropes. Two patients required non-invasive respiratory support for dyspnea and one patient had biventricular dysfunction. All received empiric antibiotics, low-molecular weight heparin, steroids, and intravenous immunoglobulin. One patient succumbed, while others recovered well. Conclusions MIS-C may be a late presentation in adolescent with COVID-19. Individualized treatment with empiric antibiotics, immunomodulation, and thromboprophylaxis can result in significantly better outcome.


2006 ◽  
Vol 64 (3a) ◽  
pp. 676-680 ◽  
Author(s):  
Fernando Campos Gomes Pinto ◽  
Leandro Valiengo ◽  
Pedro Paulo Mariani Lima Santos ◽  
Hamilton Matushita ◽  
José Píndaro Pereira Plese

A case of an intracranial arterial aneurysm at internal carotid bifurcation in a 10-year-old girl is described with the special features of cerebral aneurysm which occur in children, comparing with the adults. We alert for the necessity of carefully operative technique in order to avoid damage and intraoperative rupture of the aneurysm due to the very thin vessel wall that this population can develop. Our recommendation is early surgery in these patients.


1991 ◽  
Vol 1 (3) ◽  
pp. 254-255
Author(s):  
Jane W. Newburger

Kawasaki disease is an acute vasculitis of unknown etiology that occurs predominantly in infancy and early childhood. It is characterize by fever, bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, changes in the extremities, rash, and cervical lymphadenopathy.1,2 Coronary arterial aneurysms, or ectasia, develop in approximately 15 to 25% of children with the disease, and may lead to myocardial infarction, sudden death, or chronic coronary arterial insufficiency.2–4


2015 ◽  
Vol 2 ◽  
pp. 2333794X1559964 ◽  
Author(s):  
Elis Yuexian Lee ◽  
Jean Yin Oh ◽  
Chia Yin Chong ◽  
Jonathan Tze Liang Choo ◽  
Arjandas Mahadev ◽  
...  

2000 ◽  
Vol 124 (6) ◽  
pp. 880-882
Author(s):  
Shoji Yamanaka ◽  
Yukichi Tanaka ◽  
Motoyoshi Kawataki ◽  
Rieko Ijiri ◽  
Kiyoshi Imaizumi ◽  
...  

Abstract We present an autopsy case of a 46-day-old male infant with chromosome 22q11 deletion, which is considered the primary cause of several diseases, including DiGeorge syndrome and velocardiofacial syndrome. The patient had 2 notable congenital abnormalities: multiple dissecting pulmonary arterial aneurysms distributed in both lungs and multiple jejunal atresia with apple-peel deformity. The former, a very rare pathologic condition especially in infancy, was found incidentally at autopsy and was the primary cause of death. To our knowledge, neither of these lesions has been reported previously in a patient with chromosome 22q11 deletion.


2018 ◽  
pp. bcr-2017-221456 ◽  
Author(s):  
Nichkamol Lertamornkitti ◽  
Anchalee Wangjirapan

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