scholarly journals On biosignatures for Mars

2021 ◽  
pp. 1-17
Author(s):  
Frances Westall ◽  
Keyron Hickman-Lewis ◽  
Barbara Cavalazzi ◽  
Frédéric Foucher ◽  
Laura Clodoré ◽  
...  
Keyword(s):  
Life On Mars ◽  
Lines Of Evidence ◽  
Geological Context

Abstract In this work, we address the difficulty of reliably identifying traces of life on Mars. Several independent lines of evidence are required to build a compelling body of proof. In particular, we underline the importance of correctly interpreting the geological and mineralogical context of the sites to be explored for the presence of biosignatures. We use as examples to illustrate this, ALH84001 (where knowledge of the geological context was very limited) and other terrestrial deposits, for which this could be properly established. We also discuss promising locations and formations to be explored by ongoing and future rover missions, including Oxia Planum, which, dated at 4.0 Ga, is the most ancient Mars location targeted for investigation yet.

Fluency: A trigger of familiarity for relational representations?

2019 ◽  
Vol 42 ◽  
Author(s):  
Talya Sadeh
Keyword(s):  
Memory Model ◽  
Lines Of Evidence

Abstract According to Bastin et al.’s integrative memory model, familiarity may be attributed to both entity representations and relational representations. However, the model does not specify what triggers familiarity for relational representations. I argue that fluency is a key player in the attribution of familiarity regardless of the type of representation. Two lines of evidence are reviewed in support of my claim.

Much Ado about (Practically) Nothing

2010 ◽  
Author(s):  
David Fisher
Keyword(s):  
Energy Source ◽  
Atomic Nucleus ◽  
The Sun ◽  
Scientific Journals ◽  
Rare Gases ◽  
Important Work ◽  
The Earth ◽  
Wide Range ◽  
Life On Mars ◽  
The Universe

There are eight columns in the Periodic Table. The eighth column is comprised of the rare gases, so-called because they are the rarest elements on earth. They are also called the inert or noble gases because, like nobility, they do no work. They are colorless, odorless, invisible gases which do not react with anything, and were thought to be unimportant until the early 1960s. Starting in that era, David Fisher has spent roughly fifty years doing research on these gases, publishing nearly a hundred papers in the scientific journals, applying them to problems in geophysics and cosmochemistry, and learning how other scientists have utilized them to change our ideas about the universe, the sun, and our own planet. Much Ado about (Practically) Nothing will cover this spectrum of ideas, interspersed with the author's own work which will serve to introduce each gas and the important work others have done with them. The rare gases have participated in a wide range of scientific advances-even revolutions-but no book has ever recorded the entire story. Fisher will range from the intricacies of the atomic nucleus and the tiniest of elementary particles, the neutrino, to the energy source of the stars; from the age of the earth to its future energies; from life on Mars to cancer here on earth. A whole panoply that has never before been told as an entity.

scholarly journals Response to Comment on “Circadian rhythms in the absence of the clock gene Bmal1”

Science ◽  
2021 ◽  
Vol 372 (6539) ◽  
pp. eabf1941
Author(s):  
Sandipan Ray ◽  
Utham K. Valekunja ◽  
Alessandra Stangherlin ◽  
Steven A. Howell ◽  
Ambrosius P. Snijders ◽  
...  
Keyword(s):  
Circadian Rhythms ◽  
Clock Gene ◽  
Statistical Significance ◽  
Statistical Measures ◽  
Statistical Algorithm ◽  
Low Amplitude ◽  
Lines Of Evidence

Abruzzi et al. argue that transcriptome oscillations found in our study in the absence of Bmal1 are of low amplitude, statistical significance, and consistency. However, their conclusions rely solely on a different statistical algorithm than we used. We provide statistical measures and additional analyses showing that our original analyses and observations are accurate. Further, we highlight independent lines of evidence indicating Bmal1-independent 24-hour molecular oscillations.

scholarly journals Animating Idolatry: Making Ancestral Kin and Personhood in Ancient Peru

Religions ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 287
Author(s):  
George F. Lau
Keyword(s):  
Family Members ◽  
Small Scale ◽  
Shed Light ◽  
Lines Of Evidence ◽  
Ritual Practices

Historical and archaeological records help shed light on the production, ritual practices, and personhood of cult objects characterizing the central Peruvian highlands after ca. AD 200. Colonial accounts indicate that descendant groups made and venerated stone images of esteemed forebears as part of small-scale local funerary cults. Prayers and supplications help illuminate how different artifact forms were seen as honored family members (forebears, elders, parents, siblings). Archaeology, meanwhile, shows the close associations between carved monoliths, tomb repositories, and restricted cult spaces. The converging lines of evidence are consistent with the hypothesis that production of stone images was the purview of family/lineage groups. As the cynosures of cult activity and devotion, the physical forms of ancestor effigies enabled continued physical engagements, which vitalized both the idol and descendant group.

Volatile Anesthetics Affect Nutrient Availability in Yeast

Genetics ◽  
2002 ◽  
Vol 161 (2) ◽  
pp. 563-574
Author(s):  
Laura K Palmer ◽  
Darren Wolfe ◽  
Jessica L Keeley ◽  
Ralph L Keil
Keyword(s):  
Amino Acids ◽  
Nutrient Availability ◽  
Wild Type Strain ◽  
Volatile Anesthetic ◽  
Volatile Anesthetics ◽  
Wild Type ◽  
Anesthetic Exposure ◽  
Sites Of Action ◽  
Insight Into ◽  
Lines Of Evidence

Abstract Volatile anesthetics affect all cells and tissues tested, but their mechanisms and sites of action remain unknown. To gain insight into the cellular activities of anesthetics, we have isolated genes that, when overexpressed, render Saccharomyces cerevisiae resistant to the volatile anesthetic isoflurane. One of these genes, WAK3/TAT1, encodes a permease that transports amino acids including leucine and tryptophan, for which our wild-type strain is auxotrophic. This suggests that availability of amino acids may play a key role in anesthetic response. Multiple lines of evidence support this proposal: (i) Deletion or overexpression of permeases that transport leucine and/or tryptophan alters anesthetic response; (ii) prototrophic strains are anesthetic resistant; (iii) altered concentrations of leucine and tryptophan in the medium affect anesthetic response; and (iv) uptake of leucine and tryptophan is inhibited during anesthetic exposure. Not all amino acids are critical for this response since we find that overexpression of the lysine permease does not affect anesthetic sensitivity. These findings are consistent with models in which anesthetics have a physiologically important effect on availability of specific amino acids by altering function of their permeases. In addition, we show that there is a relationship between nutrient availability and ubiquitin metabolism in this response.

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