Ogilvie's syndrome presented with delirium in an older lady with corticobasal syndrome

2021 ◽  
pp. 1-3
Author(s):  
Feyza Mutlay ◽  
Derya Kaya ◽  
Ahmet Turan Isik

Abstract Objective Corticobasal syndrome (CBS) is one of an atypical parkinsonian syndromes characterized by extrapyramidal features as well as cortical involvement signs. A variety of factors may lead to delirium in older adults with chronic progressive life-limiting neurological illnesses like CBS. Ogilvie's syndrome (OS) is an acute colonic pseudo-obstruction in which abdominal distension, nausea, vomiting, and constipation can be seen. We report a case of OS identified as the underlying possible cause of delirium in an 80-year-old woman with CBS. We also discuss the importance of holistic approach which is essential to manage the underlying cause and to preserve the quality of life in particular for the frail geriatric population who potentially needs palliative care or already benefits from palliative care. Method An older patient with CBS presented with symptoms similar to that of acute colonic obstruction and subsequently developed delirium. The patient was found to have colonic pseudo-obstruction (OS). Result Neostigmin infusion was therefore given to treat it and delirium was resolved. Significance of results To the best of our knowledge, clinical manifestation of delirium as OS in a patient with CBS has not been previously reported. OS may be superimposed to CBS in older patients, and OS in such patients may play a role as a precipitating factor for the development of delirium. Given the fact that CBS is progressive and rare neurodegenerative disease and almost all of these patients need palliative care, eventually, health-care professionals, especially in palliative care, should be aware of distinctive challenges of life-limiting chronic neurological illnesses, such as conditions that may lead to the development of acute colonic pseudo-obstruction because the rapid treatment of them prevents the use of potentially harmful drugs, surgical procedures, or inappropriate interventions.

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Pradhum Ram ◽  
Abhinav Goyal ◽  
Marvin Lu ◽  
Joshua Sloan ◽  
William McElhaugh

Ogilvie’s syndrome (OS) is a functional obstruction of the bowel due to an autonomic imbalance. It often presents with diarrhea and is associated with hypokalemia. We present a case of a 70-year-old male who developed severe abdominal distension, watery diarrhea, and persistent hypokalemia status after left hip arthroplasty after suffering from a femoral neck fracture due to a fall and was diagnosed with OS. The persistent hypokalemia was slow to improve despite aggressive repletion because of the high potassium losses in the stool. This is most likely mediated through the increased expression of BK channels in the colonic mucosa. Aldosterone is theorized to have a role in the regulation of BK channels. Spironolactone was subsequently given and resulted in marked improvement of the diarrhea and hypokalemia. Thus, this case suggests a novel therapeutic approach for the treatment of Ogilvie’s syndrome-associated diarrhea and hypokalemia.


2005 ◽  
Vol 24 (9) ◽  
pp. 481-483 ◽  
Author(s):  
Sahin Aslan ◽  
Fatih Bilge ◽  
Bulent Aydinli ◽  
Tarik Ocak ◽  
Mustafa Uzkeser ◽  
...  

Amitraz is an insecticide/acaricide of formamidine pesticides used worldwide for ectoparasites in animals. Because of its widespread use, amitraz poisoning is frequently encountered in Turkey. Case report: A 36-year-old, comatose female was admitted to the hospital. Although it was stated that she had taken a glass of water containing amitraz, the exact volume of the substance was unknown. On admission, her Glasgow Coma Scale score was 10/15. Clinical findings were vomiting, miosis, bradycardia and hypotension. The patient's vital signs were body temperature 37.28C, pulse 54 bpm, blood pressure 80/50 mmHg and pulse-oximetry 84%. Supportive treatment consisting of oxygen, fluid replacement and gastric lavage, activated charcoal and atropine was administered. On the second day, signs of Ogilvie's syndrome characterized by severe tenderness, distension and pain in the abdomen were seen. On the third day, the patient's condition improved except for abdominal distension and pain, inability to pass faeces or flatus through the anus. Although continuous nasogastric tube decompression was performed, her complaints were not resolved completely. Neostigmine was administered on the fourth day. On the fifth day, abdominal pain and distension were decreased, and stool passage began. She had a complete clinical and laboratory improvement, which warranted her discharge on the seventh day of admission.


BMJ ◽  
1950 ◽  
Vol 2 (4670) ◽  
pp. 108-108
Author(s):  
A. J. Hobson

2020 ◽  
pp. 1-3
Author(s):  
Renato Costi ◽  
Federico Marchesi ◽  
Filippo Montali ◽  
Gerardo Palmieri ◽  
Renato Costi

Bochdalek hernia is a congenital left diaphragmatic hernia (CDH), usually diagnosed in children following the onset of thoracic symptoms such as dyspnea or tachycardia. Ogilvie’s syndrome (or acute colonic pseudo-obstruction) may be due to several conditions, including neurologic diseases, neuroleptic therapy and systemic syndromes, and is characterized by massive colon dilation in the absence of mechanical obstruction or toxic mega-colon. Sigmoid volvulus, consisting of sigmoid rotation around its axis, is a relatively frequent cause of large bowel obstruction. The three simultaneous conditions in the same patient in an emergency setting are rare, leading to a challenging situation concerning diagnosis and management. Here, we report the case of a mentally disabled 59-year-old female presenting with colonic obstruction caused by sigmoid volvulus after several episodes of Ogilvie’s syndrome-related pseudo-occlusion, found to have a giant left-sided Bochdalek diaphragmatic hernia. The patient was treated by an emergency laparoscopic approach. Despite the resolution of the abdominal picture, the patient died on postoperative day 15 by respiratory failure.


BMJ ◽  
1949 ◽  
Vol 1 (4611) ◽  
pp. 890-891 ◽  
Author(s):  
J. A. Dunlop

2014 ◽  
Vol 14 (3) ◽  
pp. 255-258 ◽  
Author(s):  
Kristopher G. Hooten ◽  
Seth F. Oliveria ◽  
Shawn D. Larson ◽  
David W. Pincus

Ogilvie's syndrome is a rare and potentially fatal disease that can easily be mistaken for postoperative ileus. Also known as acute colonic pseudo-obstruction, early recognition and diagnosis of the syndrome allows for treatment prior to bowel perforation and requisite abdominal surgery. The authors report a case of Ogilvie's syndrome following spinal deformity correction and tethered cord release in an adolescent who presented with acute abdominal distension, nausea, and vomiting on postoperative Day 0. The patient was initially diagnosed with adynamic ileus and treated conservatively with bowel rest, reduction in narcotic dosage, and a regimen of stool softeners, laxatives, and enemas. Despite this treatment, her clinical course failed to improve, and she demonstrated significant colonic distension radiographically. Intravenous neostigmine was administered as a bolus with a rapid and dramatic response. This case is the first reported instance of neostigmine use for Ogilvie's syndrome treatment following a pediatric neurosurgical operation.


2020 ◽  
Vol 19 (4) ◽  
pp. 157-162
Author(s):  
Leah Hawkins ◽  
Sunny Ajayi

A 36-year-old woman presented to maternity unit two days post caesarean section (CS) with abdominal distension, pain and constipation. She was found to be septic on admission. Imaging demonstrated dilated bowel loops without an identifiable site of obstruction highlighting Ogilvie’s syndrome (OS) as the cause of her symptoms. Hospital acquired pneumonia (HAP) was identified as the source of infection with accompanying right sided lower lobe collapse. She was reviewed by multiple specialties to aid management and was subsequently managed conservatively for pseudo-obstruction. She made a good recovery and was able to return home after 10 days in hospital.


2004 ◽  
Vol 63 (3) ◽  
pp. 427-429 ◽  
Author(s):  
Katherine Hopkins

The World Health Organization's (1990) definition of palliative care describes an holistic approach to care for patients with advanced progressive illness. Issues relating to nutrition, lack of appetite and the subsequent weight loss the individuals may experience present a challenge to all concerned with providing both formal and informal care to this patient group. The philosophy of palliative care requires a multidisciplinary approach to the constellation of issues and problems related to food that are faced by both patients and carers in receipt of palliative care. The literature in this area is mainly related to those patients with a cancer diagnosis. The developing role of palliative care in patients with non-malignant disease provides further challenges for health care professionals. The present paper aims to reflect an entire philosophical approach to care through an examination of one area of practice.


Author(s):  
Syed Uzair Mahmood ◽  
Maheen Zaidi ◽  
Syeda Kashaf Zaidi ◽  
Hanaa Tariq ◽  
Mohammad Yasir Umer

Ogilvie’s syndrome (OS) or acute pseudo-obstruction of the large bowel, is a rare condition and the true incidence is unknown. We present a case of acute colonic pseudo-obstruction (OS) post cesarean section in a 35-year-old patient with fetal distress, following cesarean delivery at term under general anesthesia. On the second postoperative day, she complained of abdominal distension, pain, nausea, vomiting, bloating and no passage of stool. As the patient's condition did not improve, she continued to have persistent abdominal distention. A plain abdominal film was taken and abdominal ultrasound was done, which showed massive gaseous distention of the bowels without fluid level. At laparotomy, a huge distended gut, pussy flakes on intestine, and massive dilatation of the whole colon were found. Postoperatively, the patient was managed with fluids, antibiotics, nutritional support, etc., along with the standard guidelines for management of peritonitis. The patient recovered and was discharged after 1 day of intensive care unit management to the ward. The need for awareness about the syndrome and early diagnosis is emphasized. 


BMJ ◽  
1949 ◽  
Vol 2 (4639) ◽  
pp. 1267-1269 ◽  
Author(s):  
J. A. Macfarlane ◽  
S. K. Kay

Sign in / Sign up

Export Citation Format

Share Document