scholarly journals Silica Coated Paper Substrate for Paper-Spray Analysis of Therapeutic Drugs in Dried Blood Spots

2011 ◽  
Vol 84 (2) ◽  
pp. 931-938 ◽  
Author(s):  
Zhiping Zhang ◽  
Wei Xu ◽  
Nicholas E. Manicke ◽  
R. Graham Cooks ◽  
Zheng Ouyang

2016 ◽  
Vol 88 (14) ◽  
pp. 7005-7013 ◽  
Author(s):  
Yajun Zheng ◽  
Qian Wang ◽  
Xiaoting Wang ◽  
Ying Chen ◽  
Xuan Wang ◽  
...  


2014 ◽  
pp. 298-313 ◽  
Author(s):  
Jiangjiang Liu ◽  
Nicholas E. Manicke ◽  
R. Graham Cooks ◽  
Zheng Ouyang


2017 ◽  
Vol 9 (43) ◽  
pp. 6117-6123 ◽  
Author(s):  
Thais P. P. Mendes ◽  
Igor Pereira ◽  
Marcella Rodrigues Ferreira ◽  
Andréa Rodrigues Chaves ◽  
Boniek Gontijo Vaz

Molecularly imprinted polymer-coated paper substrate was used for highly sensitive analysis using paper spray mass spectrometry.



2017 ◽  
Vol 89 (15) ◽  
pp. 7988-7995 ◽  
Author(s):  
Teng Wang ◽  
Yajun Zheng ◽  
Xiaoting Wang ◽  
Daniel E. Austin ◽  
Zhiping Zhang


The Analyst ◽  
2015 ◽  
Vol 140 (23) ◽  
pp. 8048-8056 ◽  
Author(s):  
Qian Wang ◽  
Yajun Zheng ◽  
Xiaoling Zhang ◽  
Xiaoxiao Han ◽  
Teng Wang ◽  
...  

A novel silica coated paper substrate has been developed, which demonstrated a high capacity for direct analysis of pesticides in paper spray mass spectrometry.



2016 ◽  
Vol 409 (1) ◽  
pp. 121-131 ◽  
Author(s):  
Karen E. Yannell ◽  
Kristina R. Kesely ◽  
Huynh Dinh Chien ◽  
Candice B. Kissinger ◽  
R. Graham Cooks


2011 ◽  
Vol 44 (06) ◽  
Author(s):  
L Mercolini ◽  
G Fulgenzi ◽  
M Melis ◽  
G Boncompagni ◽  
LJ Albers ◽  
...  


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Niclas Roxhed ◽  
Annika Bendes ◽  
Matilda Dale ◽  
Cecilia Mattsson ◽  
Leo Hanke ◽  
...  

AbstractSerological testing is essential to curb the consequences of the COVID-19 pandemic. However, most assays are still limited to single analytes and samples collected within healthcare. Thus, we establish a multianalyte and multiplexed approach to reliably profile IgG and IgM levels against several versions of SARS-CoV-2 proteins (S, RBD, N) in home-sampled dried blood spots (DBS). We analyse DBS collected during spring of 2020 from 878 random and undiagnosed individuals from the population in Stockholm, Sweden, and use classification approaches to estimate an accumulated seroprevalence of 12.5% (95% CI: 10.3%–14.7%). This includes 5.4% of the samples being IgG+IgM+ against several SARS-CoV-2 proteins, as well as 2.1% being IgG−IgM+ and 5.0% being IgG+IgM− for the virus’ S protein. Subjects classified as IgG+ for several SARS-CoV-2 proteins report influenza-like symptoms more frequently than those being IgG+ for only the S protein (OR = 6.1; p < 0.001). Among all seropositive cases, 30% are asymptomatic. Our strategy enables an accurate individual-level and multiplexed assessment of antibodies in home-sampled blood, assisting our understanding about the undiagnosed seroprevalence and diversity of the immune response against the coronavirus.



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