scholarly journals Ratiometric Near-Infrared Fluorescent Probes Based On Through-Bond Energy Transfer and π-Conjugation Modulation between Tetraphenylethene and Hemicyanine Moieties for Sensitive Detection of pH Changes in Live Cells

2018 ◽  
Vol 29 (4) ◽  
pp. 1406-1418 ◽  
Author(s):  
Jianbo Wang ◽  
Shuai Xia ◽  
Jianheng Bi ◽  
Mingxi Fang ◽  
Wafa Mazi ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Fluorescent Probes ◽  
Bond Energy ◽  
Near Infrared ◽  
Sensitive Detection ◽  
Live Cells ◽  
Ph Changes

scholarly journals Ratiometric fluorescent probes based on through-bond energy transfer of cyanine donors to near-infrared hemicyanine acceptors for mitochondrial pH detection and monitoring of mitophagy

2020 ◽  
Vol 8 (8) ◽  
pp. 1603-1615 ◽  
Author(s):  
Shuai Xia ◽  
Jianbo Wang ◽  
Yibin Zhang ◽  
Nick Whisman ◽  
Jianheng Bi ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Fluorescent Probes ◽  
Bond Energy ◽  
Near Infrared ◽  
Ph Changes ◽  
Highly Efficient ◽  
Ph Detection

Two ratiometric near-infrared fluorescent probes (A and B) have been developed to selectively and accurately detect mitochondrial pH changes based on highly efficient through-bond energy transfer (TBET) from cyanine donors to near-infrared-emissive hemicyanine acceptors.

scholarly journals Luminescent Probes for Sensitive Detection of pH Changes in Live Cells through Two Near-Infrared Luminescence Channels

ACS Sensors ◽  
2017 ◽  
Vol 2 (7) ◽  
pp. 924-931 ◽  
Author(s):  
Shuwei Zhang ◽  
Tzu-Ho Chen ◽  
Hsien-Ming Lee ◽  
Jianheng Bi ◽  
Avik Ghosh ◽  
...  
Keyword(s):  
Near Infrared ◽  
Sensitive Detection ◽  
Live Cells ◽  
Luminescent Probes ◽  
Ph Changes ◽  
Infrared Luminescence

scholarly journals Fluorescent probes for sensitive and selective detection of pH changes in live cells in visible and near-infrared channels

2017 ◽  
Vol 5 (48) ◽  
pp. 9579-9590 ◽  
Author(s):  
Mingxi Fang ◽  
Rashmi Adhikari ◽  
Jianheng Bi ◽  
Wafa Mazi ◽  
Nethaniah Dorh ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Live Cells ◽  
Selective Detection ◽  
Ph Changes ◽  
Ring Structures

Five fluorescent probes bearing coumarin moieties with spirolactam ring structures have been developed to detect pH changes in visible and near-infrared channels.

scholarly journals Near-infrared fluorescent probes based on TBET and FRET rhodamine acceptors with different pKa values for sensitive ratiometric visualization of pH changes in live cells

2019 ◽  
Vol 7 (2) ◽  
pp. 198-209 ◽  
Author(s):  
Jianbo Wang ◽  
Shuai Xia ◽  
Jianheng Bi ◽  
Yibin Zhang ◽  
Mingxi Fang ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Live Cells ◽  
Pka Values ◽  
Ph Changes ◽  
Ph Variations

Three near-infrared ratiometric fluorescent probes with different pKa values were synthesized to achieve sensitive ratiometric visualization of pH variations in lysosomes.

scholarly journals New near-infrared rhodamine dyes with large Stokes shifts for sensitive sensing of intracellular pH changes and fluctuations

2018 ◽  
Vol 54 (55) ◽  
pp. 7625-7628 ◽  
Author(s):  
Yibin Zhang ◽  
Shuai Xia ◽  
Mingxi Fang ◽  
Wafa Mazi ◽  
Yanbo Zeng ◽  
...  
Keyword(s):  
Intracellular Ph ◽  
Near Infrared ◽  
Sensitive Detection ◽  
Amine Group ◽  
Ph Changes ◽  
Stokes Shifts ◽  
Rhodamine Dyes

New near-infrared rhodamine dyes with large Stokes shifts were developed and applied for sensitive detection of cellular pH changes and fluctuations by incorporating an additional amine group with fused rings.

Turn-on visible and ratiometric near-infrared fluorescent probes for distinction endogenous esterases and chymotrypsins in live cells

2020 ◽  
Vol 306 ◽  
pp. 127567 ◽  
Author(s):  
Jiemin Wang ◽  
Zhidong Teng ◽  
Ting Cao ◽  
Jing Qian ◽  
Lei Zheng ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Live Cells ◽  
Turn On

Near‐Infrared Bioluminescence Imaging with a through‐Bond Energy Transfer Cassette

ChemBioChem ◽  
2019 ◽  
Vol 20 (15) ◽  
pp. 1919-1923 ◽  
Author(s):  
Masahiro Abe ◽  
Ryo Nishihara ◽  
Yuma Ikeda ◽  
Takahiro Nakajima ◽  
Moritoshi Sato ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Bond Energy ◽  
Near Infrared ◽  
Bioluminescence Imaging

scholarly journals Detecting Zn(II) Ions in Live Cells with Near-Infrared Fluorescent Probes

Molecules ◽  
2019 ◽  
Vol 24 (8) ◽  
pp. 1592 ◽  
Author(s):  
Fang ◽  
Xia ◽  
Bi ◽  
Wigstrom ◽  
Valenzano ◽  
...  
Keyword(s):  
Detection Limit ◽  
Oxygen Atom ◽  
Membrane Permeability ◽  
Fluorescent Probes ◽  
Near Infrared ◽  
Emission Spectra ◽  
Live Cells ◽  
Phenolic Oxygen ◽  
Acetyl Group ◽  
Low Cytotoxicity

Two near-infrared fluorescent probes (A and B) containing hemicyanine structures appended to dipicolylamine (DPA), and a dipicolylamine derivative where one pyridine was substituted with pyrazine, respectively, were synthesized and tested for the identification of Zn(II) ions in live cells. In both probes, an acetyl group is attached to the phenolic oxygen atom of the hemicyanine platform to decrease the probe fluorescence background. Probe A displays sensitive fluorescence responses and binds preferentially to Zn(II) ions over other metal ions such as Cd2+ ions with a low detection limit of 0.45 nM. In contrast, the emission spectra of probe B is not significantly affected if Zn(II) ions are added. Probe A possesses excellent membrane permeability and low cytotoxicity, allowing for sensitive imaging of both exogenously supplemented Zn(II) ions in live cells, and endogenously releases Zn(II) ions in cells after treatment of 2,2-dithiodipyridine.

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