Severe Toxic Effects on Pelagic Copepods from Maritime Exhaust Gas Scrubber Effluents

Karwinskia humboldtiana is a poisonous plant that grows in semi desertic areas in north and central México. It produces several substances with different toxic effects. One of them designated T-514 damages severely the lung, kidney and liver, producing in the hepatoeyte large intracellular fat deposits and necrosis. Preliminary observations demonstrated that three is a decrease in the amount of peroxisomes in the hepatocytes of experimentally intoxicated rats and monkeys. To study the effect exerted by the T-514 on peroxisomes, a yeast model was selected, thus, three species: Saccha romices cerevisiae, Ilansenula polymorpha and Candida boidinii were used, because there is information concerning their peroxisome's morphology, enzyme content, biological behaviour under different culture conditions and biogenesis.

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Some Conditions Necessary for Pinocytosis

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100100457 ◽

1968 ◽

Vol 26 ◽

pp. 142-143

Author(s):

M. W. Brightman

Keyword(s):

Smooth Muscle ◽

Cell Membrane ◽

Toxic Effects ◽

Cytological Evidence ◽

Cell Processes

The cytological evidence for pinocytosis is the focal infolding of the cell membrane to form surface pits that eventually pinch off and move into the cytoplasm. This activity, which can be inhibited by oxidative and glycolytic poisons, is performed only by cell processes that are at least 300A wide. However, the interpretation of such toxic effects becomes equivocal if the membrane invaginations do not normally lead to the formation of migratory vesicles, as in some endothelia and in smooth muscle. The present study is an attempt to set forth some conditions under which pinocytosis, as distinct from the mere inclusion of material in surface invaginations, can take place.

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Toxic effects of aerosol propellants on the heart

Archives of Internal Medicine ◽

10.1001/archinte.131.1.162 ◽

1973 ◽

Vol 131 (1) ◽

pp. 162-166 ◽

Cited By ~ 11

Author(s):

W. S. Harris

Keyword(s):

Toxic Effects

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The New Forest Suicide Prevention Initiative (NFSPI)

Crisis ◽

10.1027/0227-5910.26.1.25 ◽

2005 ◽

Vol 26 (1) ◽

pp. 25-33 ◽

Cited By ~ 20

Author(s):

Elizabeth King ◽

Neil Frost

Keyword(s):

Environmental Issues ◽

Exhaust Gas ◽

Telephone Number ◽

Forestry Commission ◽

Car Exhaust ◽

Gas Poisoning ◽

Car Park ◽

Annual Total ◽

New Forest ◽

Car Exhaust Gas

Abstract. A retrospective suicide study revealed that the Forestry Commission car parks in the New Forest in southern England were a previously unrecognized magnet for nonlocal suicides, attracting as high a proportion of “visitors” (35/43 in 1993-97) as among suicides who jumped from the cliffs at the infamous Beachy Head (39/48 in 1993-97). Over 95% of the car park suicides died from car exhaust gas poisoning. A multiagency initiative aimed to reduce the number of suicides in the 140 New Forest car parks where restricting access was impossible, and environmental issues paramount. Signs displaying the Samaritans' national telephone number were erected in the 26 car parks in which 50% of the car park suicides had occurred. Numbers, location, and residence of all car park deaths were monitored for 3 years. Corresponding changes in other forest registration districts were also monitored. During the 3-year intervention period the number of car park suicides fell significantly from 10/year, 1988-1997, to 3.3/year. The average annual total number of suicides in the New Forest registration district also decreased. No significant changes were found in comparable forest districts. The number of suicides in the New Forest car parks remained low during the 2 years following the evaluation.

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