Rational Development of a New Reaction-Based Ratiometric Fluorescent Probe with a Large Stokes Shift for Selective Detection of Bisulfite in Tap Water, Real Food Samples, Onion Tissues, and Zebrafish

2021 ◽  
Author(s):  
Gangqiang Yuan ◽  
Liyi Zhou ◽  
Qiaomei Yang ◽  
Haiyuan Ding ◽  
Libin Tan ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Tap Water ◽  
Stokes Shift ◽  
Food Samples ◽  
Selective Detection ◽  
Large Stokes Shift ◽  
Rational Development ◽  
Ratiometric Fluorescent Probe

Rational Design of a Two-Photon Ratiometric Fluorescent Probe for Hypochlorous Acid with a Large Stokes Shift

2020 ◽  
Vol 92 (16) ◽  
pp. 11029-11034 ◽  
Author(s):  
Long He ◽  
Haiqing Xiong ◽  
Benhua Wang ◽  
Yun Zhang ◽  
Jingpei Wang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Rational Design ◽  
Hypochlorous Acid ◽  
Stokes Shift ◽  
Large Stokes Shift ◽  
Two Photon ◽  
Ratiometric Fluorescent Probe

scholarly journals An effective colorimetric and ratiometric fluorescent probe based FRET with a large Stokes shift for bisulfite

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Wen-Li Wu ◽  
Zhao-Yang Wang ◽  
Xi Dai ◽  
Jun-Ying Miao ◽  
Bao-Xiang Zhao
Keyword(s):  
Fluorescent Probe ◽  
Stokes Shift ◽  
Large Stokes Shift ◽  
Ratiometric Fluorescent Probe

scholarly journals A Phenothiazine-HPQ Based Fluorescent Probe with a Large Stokes Shift for Sensing Biothiols in Living Systems

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2337
Author(s):  
Yan Zheng ◽  
Peng Hou ◽  
Yu Li ◽  
Jingwen Sun ◽  
Hongxia Cui ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Enhancement ◽  
Stokes Shift ◽  
Redox Properties ◽  
Living Systems ◽  
Selective Detection ◽  
Large Stokes Shift ◽  
Low Cytotoxicity ◽  
Mcf 7

Due to the redox properties closely related to numerous physiological and pathological processes, biothiols, including cysteine (Cys), homocysteine (Hcy) and glutathione (GSH), have received considerable attention in biological science. On account of the important physiological roles of these biothiols, it is of profound significance to develop sensitive and selective detection of biothiols to understand their biological profiles. In this work, we reported an efficient fluorescent probe, PHPQ-SH, for detecting biothiols in vitro and vivo, based on the phenothiazine-HPQ skeleton, with DNBS (2,4-dinitrobenzenesulfonate) as the response unit. Probe PHPQ-SH exhibited brilliant sensing performances toward thiols, including a large Stokes shift (138 nm), excellent sensitivity (for GSH, LOD = 18.3 nM), remarkable fluorescence enhancement (163-fold), low cytotoxicity, rapid response (8 min), and extraordinary selectivity. Finally, the probe PHPQ-SH illustrated herein was capable of responding and visualizing biothiols in MCF-7 cells and zebrafish.

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