scholarly journals Studying the Effects of ACE2 Mutations on the Stability, Dynamics, and Dissociation Process of SARS-CoV-2 S1/hACE2 Complexes

2020 ◽  
Vol 19 (11) ◽  
pp. 4609-4623 ◽  
Author(s):  
Hamid Hadi-Alijanvand ◽  
Maryam Rouhani
Keyword(s):  
Dissociation Process ◽  
Stability Dynamics ◽  
The Stability

scholarly journals Stability Constant of Rare Earth Metals with Substituted Thiazoles at 298.15K

2016 ◽  
Vol 64 ◽  
pp. 106-109
Author(s):  
A.B. Naik ◽  
M.S. Poharkar
Keyword(s):  
Rare Earth ◽  
Ionic Strength ◽  
Stability Constant ◽  
Rare Earth Metal ◽  
Rare Earth Metals ◽  
Sodium Perchlorate ◽  
Earth Metal ◽  
Water Mixture ◽  
Dissociation Process ◽  
The Stability

The stability constant on complexation of rare earth metal ions Eu (III), Gd (III), Nd (III) and Tb (III) with substituted thiazole in 70% Dioxane (Dx)-water mixture have been determined by a pH and spectrophotometric method at 298.15K and ionic strength 0.1mol.dm-3(sodium perchlorate). At constant temperature, the stability constant of the formed complexes decreases in the order Tb (III), Gd (III), Eu (III), Nd (III). The dissociation process is non-spontaneous, endothermic and entrophically unfavorable while formation of metal complexes has been found to be spontaneous, endothermic and entrophically favorable.

scholarly journals Modeling the stability dynamics of Ukrainian banking system

2013 ◽  
Vol 8 (2) ◽  
pp. 55-62 ◽  
Author(s):  
Olha Kozmenko ◽  
◽  
Olha Kuzmenko ◽  
Keyword(s):  
Banking System ◽  
Stability Dynamics ◽  
The Stability

Potentiometric and thermodynamic studies of 3-methyl-1-phenyl-{p-[N-(pyrimidin-2-yl)-sulfamoyl]phenylazo}-2-pyrazolin-5-one and its metal complexes

2006 ◽  
Vol 60 (1) ◽  
Author(s):  
A. Fouda ◽  
A. Al-Sarawy ◽  
E. El-Katori
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Stability Constants ◽  
Dissociation Constants ◽  
Transition Metal Ions ◽  
Effect Of Temperature ◽  
Water Mixture ◽  
Dissociation Process ◽  
The Stability ◽  
Metal Ligand

AbstractThe dissociation constants of 3-methyl-1-phenyl-{p-[N-(pyrimidin-2-yl)sulfamoyl]phenylazo}-2-pyrazolin-5-one and metal-ligand stability constants of its complexes with some transition metal ions have been determined potentiometrically in 0.1 M-KCl and ethanol—water mixture (30 vol. %). The order of the stability constants of the formed complexes increases in the sequence Mn2+, Co2+, Ni2+, Cu2+, La3+, Hf3+, UO22+, Zr4+. The effect of temperature was studied and the corresponding thermodynamic parameters (ΔG, ΔH, and ΔS) were derived and discussed. The dissociation process is nonspontaneous, endothermic, and entropically unfavourable. The formation of the metal complexes was found to be spontaneous, exothermic, and entropically favourable.

Pulse dynamics in a power-law falling film

2014 ◽  
Vol 747 ◽  
pp. 460-480 ◽  
Author(s):  
M. Pradas ◽  
D. Tseluiko ◽  
C. Ruyer-Quil ◽  
S. Kalliadasis
Keyword(s):  
Reynolds Number ◽  
Power Law ◽  
Thin Liquid Film ◽  
Small Strain ◽  
Shear Thinning ◽  
Final State ◽  
Local Flow ◽  
Stability Dynamics ◽  
The Stability ◽  
Low Dimensional

AbstractWe examine the stability, dynamics and interactions of solitary waves in a two-dimensional vertically falling thin liquid film that exhibits shear-thinning effects. We use a low-dimensional two-field model that describes the evolution of both the local flow rate and the film thickness and is consistent up to second-order terms in the long-wave expansion. The shear-thinning behaviour is modelled via a power-law formulation with a Newtonian plateau in the limit of small strain rates. Our results show the emergence of a hysteresis behaviour as the control parameter (the Reynolds number) is increased which is directly related to the shear-thinning character of the liquid and can be quantified with both linear analysis arguments and a physical interpretation. We also study pulse interactions, observing that two pulses may attract or repel each other either monotonically or in an oscillatory manner. In large domains we find that for a given Reynolds number the final state depends on the initial condition, a consequence of the presence of multiple solutions.

scholarly journals Modeling the Stability Dynamics of Ukrainian Banking System

2014 ◽  
Author(s):  
Olga Volodimirivna Kozmenko ◽  
Olha Vitaliivna Kuzmenko
Keyword(s):  
Banking System ◽  
Stability Dynamics ◽  
The Stability

scholarly journals Towards elucidating the stability, dynamics and architecture of the nucleosome remodeling and deacetylase complex by using quantitative interaction proteomics

FEBS Journal ◽  
2014 ◽  
Vol 282 (9) ◽  
pp. 1774-1785 ◽  
Author(s):  
Susan L. Kloet ◽  
H. Irem Baymaz ◽  
Matthew Makowski ◽  
Vincent Groenewold ◽  
Pascal W. T. C. Jansen ◽  
...  
Keyword(s):  
Nucleosome Remodeling ◽  
Stability Dynamics ◽  
The Stability ◽  
Interaction Proteomics

Thermodynamics of substituted pyrazolone. V: Potentiometric and conductometric studies of complexes of some transition metals with 4-(4-acetophenyl)hydrazono-3-methyl-2-pyrazolin-5-one

1999 ◽  
Vol 77 (7) ◽  
pp. 1305-1309 ◽  
Author(s):  
Ashraf A El-Bindary ◽  
Adel Z El-Sonbati ◽  
Hanan M Kera
Keyword(s):  
Thermodynamic Parameters ◽  
Stability Constants ◽  
Dissociation Constants ◽  
Transition Metal Ions ◽  
Water Mixture ◽  
Dissociation Process ◽  
Different Temperatures ◽  
The Stability ◽  
Dissociation And Stability Constants ◽  
Key Words 4

Proton-ligand dissociation constants of 4-(4-acetophenyl)hydrazono-3-methyl-2-pyrazolin-5-one (AHMP) and metal-ligand stability constants of its complexes with some transition metal ions were calculated potentiometrically in 0.1 M KCl and 50% (v/v) ethanol-water mixture. The order of stability constants was found to be Th4+ > UO22+ > Ce3+ > La3+ > Mn2+ < Co2+ < Ni2+ < Cu2+ > Zn2+. The dissociation constant, pK1H, of AHMP and the stability constants, log K, of their complexes were determined at different temperatures (298, 308, and 318 K). The corresponding thermodynamic parameters (ΔG, ΔH, and ΔS) were derived and discussed. The dissociation process is nonspontaneous, endothermic, and entropically unfavourable. The formation of the metal complexes has been found to be spontaneous, exothermic, or endothermic (depending the metal), and entropically favourable. The stoichiometries of these complexes were determined conductometrically and indicated the formation of 1:1 and 1:2 (metal:ligand) complexes. Key words: 4-(4-acetophenyl)hydrazono-3-methyl-2-pyrazolin-5-one, dissociation and stability constants, thermodynamic parameters, stoichiometries.

scholarly journals High tolerance for ionizable residues in the hydrophobic interior of proteins

2008 ◽  
Vol 105 (46) ◽  
pp. 17784-17788 ◽  
Author(s):  
Daniel G. Isom ◽  
Brian R. Cannon ◽  
Carlos A. Castañeda ◽  
Aaron Robinson ◽  
Bertrand García-Moreno E.
Keyword(s):  
Water Soluble ◽  
High Tolerance ◽  
Ph Values ◽  
Internal Ionizable Groups ◽  
Ionizable Residues ◽  
Stability Dynamics ◽  
The Stability ◽  
Structural Adaptations ◽  
Ionizable Groups ◽  
Variant Protein

Internal ionizable groups are quite rare in water-soluble globular proteins. Presumably, this reflects the incompatibility between charges and the hydrophobic environment in the protein interior. Here we show that proteins can have an inherently high tolerance for internal ionizable groups. The 25 internal positions in staphylococcal nuclease were substituted one at a time with Lys, Glu, or Asp without abolishing enzymatic activity and without detectable changes in the conformation of the protein. Similar results with substitutions of 6 randomly chosen internal positions in ribonuclease H with Lys and Glu suggest that the ability of proteins to tolerate internal ionizable groups might be a property common to many proteins. Eighty-six of the 87 substitutions made were destabilizing, but in all but one case the proteins remained in the native state at neutral pH. By comparing the stability of each variant protein at two different pH values it was established that the pKa values of most of the internal ionizable groups are shifted; many of the internal ionizable groups are probably neutral at physiological pH values. These studies demonstrate that special structural adaptations are not needed for ionizable groups to exist stably in the hydrophobic interior of proteins. The studies suggest that enzymes and other proteins that use internal ionizable groups for functional purposes could have evolved through the random accumulation of mutations that introduced ionizable groups at internal positions, followed by evolutionary adaptation and optimization to modulate stability, dynamics, and other factors necessary for function.

scholarly journals Orbits Connectivity and the False Asymptotic Behavior at Iterated Functions with Lyapunov Stability

2019 ◽  
Author(s):  
Charles Roberto Telles
Keyword(s):  
Fixed Point ◽  
Asymptotic Behavior ◽  
Lyapunov Stability ◽  
Metric Space ◽  
Average Distance ◽  
The Other ◽  
Opposite Hand ◽  
Iterated Functions ◽  
Stability Dynamics ◽  
The Stability

By defining a constant probabilistic orbit of and iterated functions, the stability dynamics of these functions in possible interactions through connectivity provides the formation of a dynamic fixed point as a metric space between both iterated functions. The presence of a dynamic fixed point identifies qualitatively phases of iteration time lengths and interaction orbits of the event. Qualitative results show that the greater the average distance from one of the functions to the fixed point of the other (all possible solutions), the higher the iteration expression on time (false asymptotic effect) of one of the functions and in the opposite hand, the lower the average distance, the higher orbit&rsquo;s interactions proximity between iterated functions (stability). This feature reveals asymptotic (well-defined) behavior between functions f and g within a well-defined Lyapunov stability.

scholarly journals JET STABILITY, DYNAMICS AND ENERGY TRANSPORT

2012 ◽  
Vol 08 ◽  
pp. 241-252 ◽  
Author(s):  
MANEL PERUCHO
Keyword(s):  
Energy Transport ◽  
State Of The Art ◽  
Maximum Amplitude ◽  
Initial Radius ◽  
Speed Of Light ◽  
Relativistic Jets ◽  
Linear Processes ◽  
Jet Stability ◽  
Stability Dynamics ◽  
The Stability

Relativistic jets carry energy and particles from compact to very large scales compared with their initial radius. This is possible due to their remarkable collimation despite their intrinsic unstable nature. In this contribution, I review the state-of-the-art of our knowledge on instabilities growing in those jets and several stabilising mechanisms that may give an answer to the question of the stability of jets. In particular, during the last years we have learned that the limit imposed by the speed of light sets a maximum amplitude to the instabilities, contrary to the case of classical jets. On top of this stabilising mechanism, the fast growth of unstable modes with small wavelengths prevents the total disruption and entrainment of jets. I also review several non-linear processes that can have an effect on the collimation of extragalactic and microquasar jets. Within those, I remark possible causes for the decollimation and deceleration of FRI jets, as opposed to the collimated FRII's. Finally, I give a summary of the main reasons why jets can propagate through such long distances.

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