3D Bioprinting of Carbohydrazide-Modified Gelatin into Microparticle-Suspended Oxidized Alginate for the Fabrication of Complex-Shaped Tissue Constructs

2020 ◽  
Vol 12 (18) ◽  
pp. 20295-20306 ◽  
Author(s):  
Dong Nyoung Heo ◽  
Mecit Altan Alioglu ◽  
Yang Wu ◽  
Veli Ozbolat ◽  
Bugra Ayan ◽  
...  
Keyword(s):  
3D Bioprinting ◽  
Tissue Constructs

A 3D bioprinting system to produce human-scale tissue constructs with structural integrity

2016 ◽  
Vol 34 (3) ◽  
pp. 312-319 ◽  
Author(s):  
Hyun-Wook Kang ◽  
Sang Jin Lee ◽  
In Kap Ko ◽  
Carlos Kengla ◽  
James J Yoo ◽  
...  
Keyword(s):  
Structural Integrity ◽  
3D Bioprinting ◽  
Tissue Constructs ◽  
Human Scale

scholarly journals Bioinks for 3D bioprinting: an overview

2018 ◽  
Vol 6 (5) ◽  
pp. 915-946 ◽  
Author(s):  
P. Selcan Gungor-Ozkerim ◽  
Ilyas Inci ◽  
Yu Shrike Zhang ◽  
Ali Khademhosseini ◽  
Mehmet Remzi Dokmeci
Keyword(s):  
Emerging Technology ◽  
3D Bioprinting ◽  
Future Perspectives ◽  
Essential Component ◽  
Tissue Constructs ◽  
Functional Tissue ◽  
Further Development

Bioprinting is an emerging technology with various applications in making functional tissue constructs to replace injured or diseased tissues. In all bioprinting strategies, the bioinks are an essential component. We provide an in-depth discussion of the different bioinks currently employed for bioprinting, and outline some future perspectives in their further development.

A graphene–polyurethane composite hydrogel as a potential bioink for 3D bioprinting and differentiation of neural stem cells

2017 ◽  
Vol 5 (44) ◽  
pp. 8854-8864 ◽  
Author(s):  
Chao-Ting Huang ◽  
Lok Kumar Shrestha ◽  
Katsuhiko Ariga ◽  
Shan-hui Hsu
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Composite Hydrogel ◽  
3D Bioprinting ◽  
Tissue Constructs ◽  
Polyurethane Composite ◽  
Associated Proteins

The composite hydrogel ink containing a small amount of graphene (25 ppm) was printed with neural stem cells (NSCs) into 3D cell-laden tissue constructs, expressing neural-associated proteins after culture for only seven days without induction.

Directly coaxial 3D bioprinting of large-scale vascularized tissue constructs

2020 ◽  
Vol 12 (3) ◽  
pp. 035014 ◽  
Author(s):  
Lei Shao ◽  
Qing Gao ◽  
Chaoqi Xie ◽  
Jianzhong Fu ◽  
Meixiang Xiang ◽  
...  
Keyword(s):  
Large Scale ◽  
3D Bioprinting ◽  
Tissue Constructs

Self-Contained Three-Dimensional Bioprinter for Applications in Cardiovascular Research

2019 ◽  
Vol 13 (3) ◽  
Author(s):  
Prabhuti Kharel ◽  
Likitha Somasekhar ◽  
Amy Vecheck ◽  
Kunal Mitra
Keyword(s):  
Functional Characterization ◽  
Three Dimensional ◽  
Environmental Parameters ◽  
3D Bioprinting ◽  
Cardiovascular Research ◽  
Form Complex ◽  
Tissue Constructs ◽  
Long Duration ◽  
Selection Of

Bioprinting is a technique of creating 3D cell-laden structures by accurately dispensing biomaterial to form complex synthetic tissue. The printed constructs aim to mimic the native tissue by preserving the cell functionality and viability within the printed structure. The 3D bioprinting system presented in this paper aims to facilitate the process of 3D bioprinting through its ability to control the environmental parameters within an enclosed printing chamber. This design of the bioprinter targets to eliminate the need for a laminar flow hood, by regulating the necessary environmental conditions important for cell survival, especially during long duration prints. A syringe-based extrusion (SBE) deposition method comprising multiple nozzles is integrated into the system. This allows for a wider selection of biomaterials that can be used for the formation of the extracellular matrix (ECM). Tissue constructs composed of alginate-gelatin hydrogels were mixed with fibrinogen and human endothelial cells which were then characterized and compared using two methodologies: casted and bioprinted. Furthermore, vasculature was incorporated in the bioprinted constructs using sacrificial printing. Structural and functional characterization of the constructs were performed by assessing rheological, mechanical properties, and analyzing live-dead assay measurements.

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