scholarly journals Responsive Hydrogel Binding Matrix for Dual Signal Amplification in Fluorescence Affinity Biosensors and Peptide Microarrays

2021 ◽  
Author(s):  
Simone Hageneder ◽  
Vanessa Jungbluth ◽  
Regina Soldo ◽  
Christian Petri ◽  
Matthias Pertiller ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Peptide Microarrays ◽  
Dual Signal Amplification ◽  
Affinity Biosensors

Experimental Validation of Digital Pre-distortion Technique for Dual-band Dual-signal Amplification by Single Feedback Architecture Employing Dual-band Mixer

2015 ◽  
Vol E98.C (3) ◽  
pp. 242-251 ◽  
Author(s):  
Ikuma ANDO ◽  
Gia KHANH TRAN ◽  
Kiyomichi ARAKI ◽  
Takayuki YAMADA ◽  
Takana KAHO ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Experimental Validation ◽  
Dual Band ◽  
Dual Signal Amplification

scholarly journals Dual-Signal Amplification Strategy for Sensitive MicroRNA Detection Based on Rolling Circle Amplification and Enzymatic Repairing Amplification

ACS Omega ◽  
2020 ◽  
Vol 5 (50) ◽  
pp. 32738-32743
Author(s):  
Fubing Xiao ◽  
Jie Liu ◽  
Qinghui Guo ◽  
Zhibo Du ◽  
Hong Li ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Rolling Circle Amplification ◽  
Rolling Circle ◽  
Microrna Detection ◽  
Amplification Strategy ◽  
Dual Signal Amplification

scholarly journals MiRNA Detection Using a Rolling Circle Amplification and RNA-Cutting Allosteric Deoxyribozyme Dual Signal Amplification Strategy

Biosensors ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 222
Author(s):  
Chenxin Fang ◽  
Ping Ouyang ◽  
Yuxing Yang ◽  
Yang Qing ◽  
Jialun Han ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Rolling Circle Amplification ◽  
Padlock Probe ◽  
Rolling Circle ◽  
Sensing Platform ◽  
Mirna Detection ◽  
Substrate Cleavage ◽  
Amplification Strategy ◽  
Circular Template ◽  
Dual Signal Amplification

A microRNA (miRNA) detection platform composed of a rolling circle amplification (RCA) system and an allosteric deoxyribozyme system is proposed, which can detect miRNA-21 rapidly and efficiently. Padlock probe hybridization with the target miRNA is achieved through complementary base pairing and the padlock probe forms a closed circular template under the action of ligase; this circular template results in RCA. In the presence of DNA polymerase, RCA proceeds and a long chain with numerous repeating units is formed. In the presence of single-stranded DNA (H1 and H2), multi-component nucleic acid enzymes (MNAzymes) are formed that have the ability to cleave substrates. Finally, substrates containing fluorescent and quenching groups and magnesium ions are added to the system to activate the MNAzyme and the substrate cleavage reaction, thus achieving fluorescence intensity amplification. The RCA–MNAzyme system has dual signal amplification and presents a sensing platform that demonstrates broad prospects in the analysis and detection of nucleic acids.

Dual signal amplification based on polysaccharide-initiated ring-opening polymerization and click polymerization for exosomes detection

Talanta ◽  
2021 ◽  
pp. 122531
Author(s):  
Xin Zhu ◽  
Zenghui Liu ◽  
Jinge Li ◽  
Zutian Li ◽  
Fuchun Si ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Click Polymerization ◽  
Dual Signal Amplification

Ultrasensitive and specific multi-miRNA detection based on dual signal amplification

2021 ◽  
Vol 337 ◽  
pp. 129745
Author(s):  
Ensheng Xu ◽  
Yahui Feng ◽  
Haitang Yang ◽  
Peng Li ◽  
Lu Kong ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Mirna Detection ◽  
Dual Signal Amplification

Sensitive electrochemical immunosensor for α-synuclein based on dual signal amplification using PAMAM dendrimer-encapsulated Au and enhanced gold nanoparticle labels

2012 ◽  
Vol 32 (1) ◽  
pp. 224-230 ◽  
Author(s):  
Yarui An ◽  
Xiaoli Jiang ◽  
Wenji Bi ◽  
Hua Chen ◽  
Litong Jin ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Signal Amplification ◽  
Pamam Dendrimer ◽  
Electrochemical Immunosensor ◽  
Dual Signal Amplification

Dual-signal amplification strategy for electrochemiluminescence sandwich biosensor for detection of thrombin

2017 ◽  
Vol 240 ◽  
pp. 742-748 ◽  
Author(s):  
Yingjie Li ◽  
Yuqin Li ◽  
Ning Xu ◽  
Jiahong Pan ◽  
Tufeng Chen ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Amplification Strategy ◽  
Dual Signal Amplification

A novel electrochemical immunosensor based on dual signal amplification of gold nanoparticles and telomerase extension reaction

2014 ◽  
Vol 6 (7) ◽  
pp. 2221-2226 ◽  
Author(s):  
Xiao-Yan Li ◽  
Zi Yi ◽  
Hao Tang ◽  
Xia Chu ◽  
Ru-Qin Yu
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Highly Sensitive ◽  
Dual Signal Amplification

Highly sensitive electrochemical immune analysis was achieved based on dual signal amplification of AuNPs and telomerase extension reaction.

Electrochemical biosensor for detection of pathogenic bacteria based on dual signal amplification of Cu3(PO4)2-mediated click chemistry and DNAzyme

The Analyst ◽  
2021 ◽  
Author(s):  
Hongguo Wei ◽  
Jiayu Wan ◽  
Shengjun Bu ◽  
Wenguang Zhang ◽  
Ma Li ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Magnetic Separation ◽  
Concanavalin A ◽  
Signal Amplification ◽  
Pathogenic Bacteria ◽  
Electrochemical Biosensor ◽  
Inorganic Hybrid ◽  
Highly Sensitive ◽  
Antibody Conjugates ◽  
Dual Signal Amplification

A novel electrochemical biosensor for detecting pathogenic bacteria was designed based on specific magnetic separation and highly sensitive click chemistry. Instead of enzyme-antibody conjugates, organic-inorganic hybrid nanoflowers (Concanavalin A (Con...

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