pH-Responsive Shape Memory Poly(ethylene glycol)–Poly(ε-caprolactone)-based Polyurethane/Cellulose Nanocrystals Nanocomposite

2015 ◽  
Vol 7 (23) ◽  
pp. 12988-12999 ◽  
Author(s):  
Ying Li ◽  
Hongmei Chen ◽  
Dian Liu ◽  
Wenxi Wang ◽  
Ye Liu ◽  
...  
2019 ◽  
Vol 10 (17) ◽  
pp. 2143-2151 ◽  
Author(s):  
Yan Zhang ◽  
Yue Xu ◽  
Chao Wei ◽  
Chuanhao Sun ◽  
Bingkun Yan ◽  
...  

A one-shot method was employed to synthesize ROS/pH responsive methoxy poly(ethylene glycol)-b-polycarbonate (mPEG-b-poly(MN-co-MSe)) with the selenide and tertiary amine groups situated on the backbone.


2013 ◽  
Vol 750-752 ◽  
pp. 1476-1479 ◽  
Author(s):  
Bin Liu ◽  
Guan Hui Gao ◽  
Peng Liu ◽  
Hu Qiang Yi ◽  
Wei Wei ◽  
...  

In this paper, we successfully designed a pH-responsive micelles based on hybrid polypeptide copolymers of poly (L-lysine-4-Azepan-1-yl-butyric)-b-poly (ethylene glycol)-b-poly (L-lysine-Diisopropylamide)-b-poly (L-leucine) (PLL(A)-PEG-PLL(B)-PLLeu) for efficient drug delivery. This pH-responsive nanoparticles were able to response to different pH values (pH=6.8 and 5.5). In vitro, these nanoparticles exhibited a stable and evenly distributed approximately 51 nm, a slightly positive potential about 10.3 mv at pH 7.4, which were crucial for the circulation of drugs in blood. While size and potential were about 130 nm and 34.7 mv at pH 6.8, which were good for drugs in membrane. Furthermore, the loading capability of DOX was up to 11.3%, and the pH-responsive release efficiency reached to 68.3% at pH 5.5. The results indicated that these micelles had huge potential application in cancer delivery.


2015 ◽  
Vol 7 (16) ◽  
pp. 8404-8411 ◽  
Author(s):  
Zhe Zhang ◽  
Qiang Lv ◽  
Xiaoye Gao ◽  
Li Chen ◽  
Yue Cao ◽  
...  

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