scholarly journals In Utero Exposure to Citalopram Mitigates Maternal Stress Effects on Fetal Brain Development

2019 ◽  
Vol 10 (7) ◽  
pp. 3307-3317 ◽  
Author(s):  
Juan C. Velasquez ◽  
Qiuying Zhao ◽  
Yen Chan ◽  
Ligia C.M. Galindo ◽  
Christelle Simasotchi ◽  
...  
Keyword(s):  
Brain Development ◽  
Maternal Stress ◽  
Fetal Brain ◽  
In Utero ◽  
In Utero Exposure ◽  
Stress Effects ◽  
Fetal Brain Development

scholarly journals Correction to “In Utero Exposure to Citalopram Mitigates Maternal Stress Effects on Fetal Brain Development”

2020 ◽  
Vol 11 (3) ◽  
pp. 484-484
Author(s):  
Juan C. Velasquez ◽  
Qiuying Zhao ◽  
Yen Chan ◽  
Ligia C. M. Galindo ◽  
Christelle Simasotchi ◽  
...  
Keyword(s):  
Brain Development ◽  
Maternal Stress ◽  
Fetal Brain ◽  
In Utero ◽  
In Utero Exposure ◽  
Stress Effects ◽  
Fetal Brain Development

scholarly journals Neuroplacentology in congenital heart disease: placental connections to neurodevelopmental outcomes

2021 ◽  
Author(s):  
Rachel L. Leon ◽  
Imran N. Mir ◽  
Christina L. Herrera ◽  
Kavita Sharma ◽  
Catherine Y. Spong ◽  
...  
Keyword(s):  
Brain Development ◽  
Congenital Heart ◽  
Fetal Brain ◽  
In Utero ◽  
Structure And Function ◽  
Brain Growth ◽  
Neurodevelopmental Outcomes ◽  
Fetal Brain Development ◽  
And Function

Abstract Children with congenital heart disease (CHD) are living longer due to effective medical and surgical management. However, the majority have neurodevelopmental delays or disorders. The role of the placenta in fetal brain development is unclear and is the focus of an emerging field known as neuroplacentology. In this review, we summarize neurodevelopmental outcomes in CHD and their brain imaging correlates both in utero and postnatally. We review differences in the structure and function of the placenta in pregnancies complicated by fetal CHD and introduce the concept of a placental inefficiency phenotype that occurs in severe forms of fetal CHD, characterized by a myriad of pathologies. We propose that in CHD placental dysfunction contributes to decreased fetal cerebral oxygen delivery resulting in poor brain growth, brain abnormalities, and impaired neurodevelopment. We conclude the review with key areas for future research in neuroplacentology in the fetal CHD population, including (1) differences in structure and function of the CHD placenta, (2) modifiable and nonmodifiable factors that impact the hemodynamic balance between placental and cerebral circulations, (3) interventions to improve placental function and protect brain development in utero, and (4) the role of genetic and epigenetic influences on the placenta–heart–brain connection. Impact Neuroplacentology seeks to understand placental connections to fetal brain development. In fetuses with CHD, brain growth abnormalities begin in utero. Placental microstructure as well as perfusion and function are abnormal in fetal CHD.

Fetal brain development of twins assessed in utero by ultrasound: implications for schizophrenia

1996 ◽  
Vol 19 (2-3) ◽  
pp. 141-149 ◽  
Author(s):  
John H. Gilmore ◽  
Diana O. Perkins ◽  
Mark A. Kliewer ◽  
Marvin L. Hage ◽  
Susan G. Silva ◽  
...  
Keyword(s):  
Brain Development ◽  
Fetal Brain ◽  
In Utero ◽  
Fetal Brain Development

Quantitative MRI measurements of human fetal brain development in utero

NeuroImage ◽  
2006 ◽  
Vol 33 (2) ◽  
pp. 463-470 ◽  
Author(s):  
Rachel Grossman ◽  
Chen Hoffman ◽  
Yael Mardor ◽  
Anat Biegon
Keyword(s):  
Brain Development ◽  
Fetal Brain ◽  
In Utero ◽  
Quantitative Mri ◽  
Human Fetal Brain ◽  
Fetal Brain Development ◽  
Mri Measurements

Techniques for in utero, longitudinal MRI of fetal brain development in baboons at 3T

Methods ◽  
2010 ◽  
Vol 50 (3) ◽  
pp. 147-156 ◽  
Author(s):  
Feng Liu ◽  
Marianne Garland ◽  
Yunsuo Duan ◽  
Raymond I. Stark ◽  
Dongrong Xu ◽  
...  
Keyword(s):  
Brain Development ◽  
Fetal Brain ◽  
In Utero ◽  
Longitudinal Mri ◽  
Fetal Brain Development

scholarly journals Mapping fetal brain development based on automated segmentation and 4D brain atlasing

2020 ◽  
Author(s):  
Haotian Li ◽  
Guohui Yan ◽  
Wanrong Luo ◽  
Tintin Liu ◽  
Yan Wang ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Brain Development ◽  
Chinese Population ◽  
Brain Mri ◽  
Fetal Brain ◽  
In Utero ◽  
Brain Atlas ◽  
Morphological Development ◽  
Brain Extraction ◽  
Fetal Brain Development

AbstractFetal brain MRI has become an important tool for in utero assessment of brain development and disorders. However, quantitative analysis of fetal brain MRI remains difficult, partially due to the limited tools for automated preprocessing and the lack of normative brain templates. In this paper, we proposed an automated pipeline for fetal brain extraction, super-resolution reconstruction, and fetal brain atlasing to quantitatively map in utero fetal brain development during mid-to-late gestation in a Chinese population. First, we designed a U-net convolutional neural network for automated fetal brain extraction, which achieved an average accuracy of 97%. We then generated a developing fetal brain atlas, using an iterative linear and nonlinear registration approach. Based on the 4D spatiotemporal atlas, we quantified the morphological development of the fetal brain between 23-36 weeks of gestation. The proposed pipeline enabled the fully-automated volumetric reconstruction for clinically available fetal brain MRI data, and the 4D fetal brain atlas provided normative templates for quantitative analysis of potential fetal brain abnormalities, especially in the Chinese population.

scholarly journals Association Between Socioeconomic Status and In Utero Fetal Brain Development

2021 ◽  
Vol 4 (3) ◽  
pp. e213526
Author(s):  
Yuan-Chiao Lu ◽  
Kushal Kapse ◽  
Nicole Andersen ◽  
Jessica Quistorff ◽  
Catherine Lopez ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Brain Development ◽  
Fetal Brain ◽  
In Utero ◽  
Fetal Brain Development
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