scholarly journals Mechanics of Mineralized Collagen Fibrils upon Transient Loads

ACS Nano ◽  
2020 ◽  
Vol 14 (7) ◽  
pp. 8307-8316
Author(s):  
Mario Milazzo ◽  
Gang Seob Jung ◽  
Serena Danti ◽  
Markus J. Buehler
Keyword(s):  
Collagen Fibrils ◽  
Transient Loads ◽  
Mineralized Collagen

scholarly journals Molecular origin of viscoelasticity in mineralized collagen fibrils

2021 ◽  
Author(s):  
Mario Milazzo ◽  
Alessio David ◽  
Gang Seob Jung ◽  
Serena Danti ◽  
Markus J. Buehler
Keyword(s):  
Collagen Fibrils ◽  
Skeletal System ◽  
Mineralized Tissue ◽  
Molecular Origin ◽  
Mineralized Collagen

Bone is mineralized tissue constituting the skeletal system, supporting and protecting body organs and tissues. In addition to such fundamental mechanical functions, bone also plays a remarkable role in sound...

Intrafibrillar Mineralization of Collagen using a Liquid-Phase Mineral Precursor

2003 ◽  
Vol 774 ◽  
Author(s):  
Matthew J. Olszta ◽  
Elliot P. Douglas ◽  
Laurie B. Gower
Keyword(s):  
Liquid Phase ◽  
Material Science ◽  
Type I Collagen ◽  
Collagen Matrix ◽  
Collagen Fibrils ◽  
Type I ◽  
Mineral Phase ◽  
Capillary Action ◽  
Acid Etch ◽  
Mineralized Collagen

AbstractIntrafibrillar mineralization of type-I collagen with hydroxyapatite (HA) is the basis of the complex biological composite known as bone, which from a material science perspective is a fascinating example of an interpenetrating bioceramic composite. Using a polymer-induced liquid-precursor (PILP) process, collagen substrates were highly infiltrated with a liquid-phase mineral precursor to calcium carbonate (CaCO3). At sections of partially mineralized collagen, banded mineral patterns were observed perpendicular to the collagen fibrils, while other fibrils were completely mineralized. An acid etch, used to preferentially remove superficial mineral, further revealed such banded patterns in fully mineralized samples. Removal of the collagen matrix with a dilute hypochlorite solution showed an interpenetrating mineral phase, with mineral disks that spanned the diameter of the pre-existing collagen fibrils, supporting our hypothesis that intrafibrillar mineralization can be achieved via capillary action applied to a liquid-phase mineral precursor.

Failure of mineralized collagen fibrils: Modeling the role of collagen cross-linking

2008 ◽  
Vol 41 (7) ◽  
pp. 1427-1435 ◽  
Author(s):  
Thomas Siegmund ◽  
Matthew R. Allen ◽  
David B. Burr
Keyword(s):  
Collagen Fibrils ◽  
Cross Linking ◽  
Collagen Cross Linking ◽  
Mineralized Collagen

scholarly journals Mechanical properties of mineralized collagen fibrils as influenced by demineralization

2008 ◽  
Vol 162 (3) ◽  
pp. 404-410 ◽  
Author(s):  
M. Balooch ◽  
S. Habelitz ◽  
J.H. Kinney ◽  
S.J. Marshall ◽  
G.W. Marshall
Keyword(s):  
Mechanical Properties ◽  
Collagen Fibrils ◽  
Mineralized Collagen

Growth of mineralized collagen films by oriented calcium fluoride nanocrystals assembly with enhanced cell proliferation

2021 ◽  
Author(s):  
Weijian Fang ◽  
Hang Ping ◽  
Ying Huang ◽  
Hao Xie ◽  
Hao Wang ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Calcium Fluoride ◽  
Collagen Fibrils ◽  
Calcified Tissue ◽  
Hydroxyapatite Nanocrystals ◽  
Inorganic Components ◽  
Mineralized Collagen

Bone is a highly calcified tissue with 60 wt% inorganic components. It is made up of mineralized collagen fibrils, where the platelet-like hydroxyapatite nanocrystals orientally deposit within collagen fibrils. Inspired...

scholarly journals Molecular mechanics of mineralized collagen fibrils in bone

2013 ◽  
Vol 4 (1) ◽  
Author(s):  
Arun K. Nair ◽  
Alfonso Gautieri ◽  
Shu-Wei Chang ◽  
Markus J. Buehler
Keyword(s):  
Molecular Mechanics ◽  
Collagen Fibrils ◽  
Mineralized Collagen

3D Random Walk Model of Diffusion in Human Hypo- and Hyper- Mineralized Collagen Fibrils

2021 ◽  
pp. 110586
Author(s):  
Fabiano Bini ◽  
Andrada Pica ◽  
Andrea Marinozzi ◽  
Franco Marinozzi
Keyword(s):  
Random Walk ◽  
Collagen Fibrils ◽  
Random Walk Model ◽  
Mineralized Collagen
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