Stable Organic Photosensitizer Nanoparticles with Absorption Peak beyond 800 Nanometers and High Reactive Oxygen Species Yield for Multimodality Phototheranostics

ACS Nano ◽  
2020 ◽  
Vol 14 (8) ◽  
pp. 9917-9928 ◽  
Author(s):  
Yingpeng Wan ◽  
Guihong Lu ◽  
Wei-Chih Wei ◽  
Yi-Hsuan Huang ◽  
Shengliang Li ◽  
...  
2015 ◽  
Vol 78 (12) ◽  
pp. 2200-2206 ◽  
Author(s):  
FANG LIU ◽  
MEI LIU ◽  
LIHUI DU ◽  
DAOYING WANG ◽  
ZHIMING GENG ◽  
...  

This study evaluated the antibacterial effect of the combination of ɛ-polylysine (ɛ-PL) and nisin against Enterococcus faecalis strains. The combination of ɛ-PL and nisin showed synergistic antibacterial activity against three Enterococcus strains. Scanning electron microscopy and a membrane permeability assay revealed that the combined treatment with ɛ-PL and nisin synergistically damaged the cell morphology of E. faecalis strain R612Z1 cells. Both ɛ-PL and nisin can dissipate the transmembrane electric potential of E. faecalis R612Z1 cells, but these peptides did not affect the transmembrane pH gradient. The combination of ɛ-PL and nisin can produce a high reactive oxygen species level in E. faecalis R612Z1 cells. The results indicated that the uptake of ɛ-PL into cells was promoted through nisin and that the combination of ɛ-PL and nisin could produce a high reactive oxygen species level in E. faecalis R612Z1 cells, leading to cell growth inhibition.


2015 ◽  
Vol 291 (1) ◽  
pp. 423-435 ◽  
Author(s):  
Jason Sims ◽  
Carlo V. Bruschi ◽  
Chloé Bertin ◽  
Nicole West ◽  
Michael Breitenbach ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e111068 ◽  
Author(s):  
Isaac Cano ◽  
Vitaly Selivanov ◽  
David Gomez-Cabrero ◽  
Jesper Tegnér ◽  
Josep Roca ◽  
...  

2009 ◽  
pp. c3 ◽  
Author(s):  
Helena M. Cochemé ◽  
Michael P. Murphy

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