scholarly journals Role of Voluminous Substituents in Controlling the Optical Properties of Disc/Planar-Like Small Organic Molecules: Toward Molecular Emission in Solid State

ACS Omega ◽  
2017 ◽  
Vol 2 (9) ◽  
pp. 5348-5356 ◽  
Author(s):  
Sunil Kumar ◽  
Meenu Singh ◽  
Pankaj Gaur ◽  
Jwo-Huei Jou ◽  
Subrata Ghosh
Keyword(s):  
Optical Properties ◽  
Solid State ◽  
Organic Molecules ◽  
Small Organic Molecules ◽  
Molecular Emission

Near-Infrared Solid-State Lasers Based on Small Organic Molecules

ACS Photonics ◽  
2019 ◽  
Vol 6 (11) ◽  
pp. 2590-2599 ◽  
Author(s):  
Jun-Jie Wu ◽  
Xue-Dong Wang ◽  
Liang-Sheng Liao
Keyword(s):  
Solid State ◽  
Near Infrared ◽  
Organic Molecules ◽  
Solid State Lasers ◽  
Small Organic Molecules

Role of spatial distortions on the quadratic nonlinear optical properties of octupolar organic and metallo-organic molecules

2007 ◽  
Vol 126 (3) ◽  
pp. 034312 ◽  
Author(s):  
Sébastien Bidault ◽  
Sophie Brasselet ◽  
Joseph Zyss ◽  
Olivier Maury ◽  
Hubert Le Bozec
Keyword(s):  
Optical Properties ◽  
Nonlinear Optical ◽  
Organic Molecules ◽  
Nonlinear Optical Properties

scholarly journals Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress

2020 ◽  
Vol 21 (6) ◽  
pp. 2002 ◽  
Author(s):  
Darcy C. Engelhart ◽  
Priti Azad ◽  
Suwayda Ali ◽  
Jeffry C. Granados ◽  
Gabriel G. Haddad ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Drosophila Melanogaster ◽  
Organic Molecules ◽  
Fruit Fly ◽  
Evolutionary Analysis ◽  
Oxygen Species ◽  
Small Organic Molecules ◽  
Evolutionarily Conserved

The SLC22 family of transporters is widely expressed, evolutionarily conserved, and plays a major role in regulating homeostasis by transporting small organic molecules such as metabolites, signaling molecules, and antioxidants. Analysis of transporters in fruit flies provides a simple yet orthologous platform to study the endogenous function of drug transporters in vivo. Evolutionary analysis of Drosophila melanogaster putative SLC22 orthologs reveals that, while many of the 25 SLC22 fruit fly orthologs do not fall within previously established SLC22 subclades, at least four members appear orthologous to mammalian SLC22 members (SLC22A16:CG6356, SLC22A15:CG7458, CG7442 and SLC22A18:CG3168). We functionally evaluated the role of SLC22 transporters in Drosophila melanogaster by knocking down 14 of these genes. Three putative SLC22 ortholog knockdowns—CG3168, CG6356, and CG7442/SLC22A—did not undergo eclosion and were lethal at the pupa stage, indicating the developmental importance of these genes. Additionally, knocking down four SLC22 members increased resistance to oxidative stress via paraquat testing (CG4630: p < 0.05, CG6006: p < 0.05, CG6126: p < 0.01 and CG16727: p < 0.05). Consistent with recent evidence that SLC22 is central to a Remote Sensing and Signaling Network (RSSN) involved in signaling and metabolism, these phenotypes support a key role for SLC22 in handling reactive oxygen species.

The design of new photochromic polymers incorporating covalently or ionically linked spiropyran/polyoxometalate hybrids

2017 ◽  
Vol 5 (25) ◽  
pp. 6343-6351 ◽  
Author(s):  
Irene Bazzan ◽  
Patricia Bolle ◽  
Olivier Oms ◽  
Hanène Salmi ◽  
Nadine Aubry-Barroca ◽  
...  
Keyword(s):  
Optical Properties ◽  
Solid State ◽  
Photochromic Polymers ◽  
Grafting Onto

Novel photochromic polymers highlight through their solid-state optical properties the key role of grafting onto the coloration and fading kinetics.

Photoexcitations in Oligothiophenes: The Role of Conformation Mobility and Intermolecular Interactions.

1999 ◽  
Vol 598 ◽  
Author(s):  
Chiara Botta ◽  
Silvia Destri ◽  
William Porzio ◽  
Gianni Bongiovanni ◽  
Andrea Mura ◽  
...  
Keyword(s):  
Optical Properties ◽  
Solid State ◽  
Intermolecular Interactions ◽  
Photophysical Properties ◽  
Supramolecular Organization ◽  
Relaxation Processes ◽  
Chain Packing ◽  
Backbone Conformation ◽  
Packing Arrangement

ABSTRACTThe optical properties of substituted and unsubstituted oligothiophenes are analysed with respect to their supramolecular organization in the solid state. The spectra typical of the isolated molecules are obtained by reducing the intermolecular interactions by both lateral chain substitution and by inclusion in a host organic crystal. The photophysical properties of the weakly interacting oligothiophenes are strongly influenced by their backbone conformation and conformational mobility. Oligomers included in the channels of a guest crystal show fast torsional relaxation processes during the photoexcitation. Powders of β-substituted oligomers display optical properties dependent on the conformation of their particular chain packing arrangement.

Labeling of Nanofiber-Forming Peptides by Site-Directed Bioconjugation: Effect of Spacer Length on Self-Assembly

2019 ◽  
Vol 16 (2) ◽  
pp. 319-325
Author(s):  
Alessandra Scelsi ◽  
Brigida Bochicchio ◽  
Antonietta Pepe
Keyword(s):  
Self Assembly ◽  
Organic Molecules ◽  
Periodate Oxidation ◽  
Photonic Devices ◽  
Serine Residue ◽  
Spacer Length ◽  
Small Organic Molecules ◽  
Self Assembling ◽  
Versatile Tool

Background: The conjugation of small organic molecules to self-assembling peptides is a versatile tool to decorate nanostructures with original functionalities. Labeling with chromophores or fluorophores, for example, creates optically active fibers with potential interest in photonic devices. Aim and Objective: In this work, we present a rapid and effective labeling procedure for a self-assembling peptide able to form nanofibers. Rapid periodate oxidation of the N-terminal serine residue of the peptide and subsequent conjugation with dansyl moiety generated fluorophore-decorated peptides. Results: Three dansyl-conjugated self-assembling peptides with variable spacer-length were synthesized and characterized and the role of the size of the linker between fluorophore and peptide in self-assembling was investigated. Our results show that a short linker can alter the self-assembly in nanofibers of the peptide. Conclusions: Herein we report on an alternative strategy for creating functionalized nanofibrils, able to expand the toolkit of chemoselective bioconjugation strategies to be used in site-specific decoration of self-assembling peptides.

scholarly journals Bent DNA Bows as Sensing Amplifiers for Detecting DNA-Interacting Salts and Molecules

Sensors ◽  
2020 ◽  
Vol 20 (11) ◽  
pp. 3112
Author(s):  
Jack Freeland ◽  
Lihua Zhang ◽  
Shih-Ting Wang ◽  
Mason Ruiz ◽  
Yong Wang
Keyword(s):  
Organic Molecules ◽  
Inorganic Salts ◽  
Dna Interactions ◽  
Bent Dna ◽  
Small Organic Molecules ◽  
Cellular Processes ◽  
Economic Methods ◽  
Simple Economic ◽  
Potential Use

Due to the central role of DNA, its interactions with inorganic salts and small organic molecules are important. For example, such interactions play important roles in various fundamental cellular processes in living systems and are involved in many DNA-damage related diseases. Strategies to improve the sensitivity of existing techniques for studying DNA interactions with other molecules would be appreciated in situations where the interactions are too weak. Here we report our development and demonstration of bent DNA bows for amplifying, sensing, and detecting the interactions of 14 inorganic salts and small organic molecules with DNA. With the bent DNA bows, these interactions were easily visualized and quantified in gel electrophoresis, which were difficult to measure without bending. In addition, the strength of the interactions of DNA with the various salts/molecules were quantified using the modified Hill equation. This work highlights the amplification effects of the bending elastic energy stored in the DNA bows and the potential use of the DNA bows for quantitatively measuring DNA interactions with small molecules as simple economic methods; it may also pave the way for exploiting the bent DNA bows for other applications such as screening DNA-interacting molecules and drugs.

Tuning of MEH-PPV electro-optical properties by incorporation of benzylidene-malononitrile-based small organic molecules

2020 ◽  
Vol 3 (5) ◽  
pp. 687-692
Author(s):  
Hassen Dhifaoui ◽  
Meenakshi Pegu ◽  
Walid Aloui ◽  
Abdelaziz Bouazizi ◽  
Samrana Kazim ◽  
...  
Keyword(s):  
Optical Properties ◽  
Organic Molecules ◽  
Small Organic Molecules ◽  
Benzylidene Malononitrile
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