Linear Cationic Click Polymers/DNA Nanoparticles: In Vitro Structure–Activity Relationship and In Vivo Evaluation for Gene Delivery

Activity Relationship ◽

In Vivo Evaluation ◽

Dna Nanoparticles ◽

Structure–Activity Relationship and in Vitro and in Vivo Evaluation of the Potent Cytotoxic Anti-microtubule AgentN-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium Chloride and Its Analogues As Antitumor Agents

Journal of Medicinal Chemistry ◽

10.1021/jm400639z ◽

2013 ◽

Vol 56 (17) ◽

pp. 6829-6844 ◽

Cited By ~ 18

Author(s):

Aleem Gangjee ◽

Ying Zhao ◽

Sudhir Raghavan ◽

Cristina C. Rohena ◽

Susan L. Mooberry ◽

...

Keyword(s):

Antitumor Agents ◽

Activity Relationship ◽

In Vivo Evaluation ◽

Novel pyrazolo[4,3-d]pyrimidine microtubule targeting agents (MTAs): Synthesis, structure–activity relationship, in vitro and in vivo evaluation as antitumor agents

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2021.127923 ◽

2021 ◽

Vol 41 ◽

pp. 127923

Author(s):

Farhana Islam ◽

Tasdique M. Quadery ◽

Ruoli Bai ◽

Lerin R. Luckett-Chastain ◽

Ernest Hamel ◽

...

Keyword(s):

Antitumor Agents ◽

Activity Relationship ◽

In Vivo Evaluation ◽

Structure Activity ◽

Microtubule Targeting Agents

Synthesis of new generation triazolyl- and isoxazolyl-containing 6-nitro-2,3-dihydroimidazooxazoles as anti-TB agents: in vitro, structure–activity relationship, pharmacokinetics and in vivo evaluation

Organic & Biomolecular Chemistry ◽

10.1039/c5ob00054h ◽

2015 ◽

Vol 13 (12) ◽

pp. 3610-3624 ◽

Cited By ~ 14

Author(s):

Gurunadham Munagala ◽

Kushalava Reddy Yempalla ◽

Samsher Singh ◽

Sumit Sharma ◽

Nitin Pal Kalia ◽

...

Keyword(s):

Activity Relationship ◽

In Vivo Evaluation ◽

Structure Activity ◽

New Generation

Promising nitroimidazoloxazole scaffold gives another novel triazolyl-containing 6-nitro-2,3-dihydroimidazooxazole as anti-TB lead.

Structure–activity relationship, in vitro and in vivo evaluation of novel dienyl sulphonyl fluorides as selective BuChE inhibitors for the treatment of Alzheimer's disease

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2021.1959571 ◽

2021 ◽

Vol 36 (1) ◽

pp. 1860-1873

Author(s):

Chengyao Wu ◽

Guijuan Zhang ◽

Zai-Wei Zhang ◽

Xia Jiang ◽

Ziwen Zhang ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Activity Relationship ◽

In Vivo Evaluation ◽

STRUCTURE-ACTIVITY RELATIONSHIP OF VARIOUS ANALOGUES OF β-CORTICOTRROPHIN DETERMINED BY REFERENCE TO VARIOUS PARAMETERS IN VITRO AND IN VIVO

Acta Endocrinologica ◽

10.1530/acta.0.061s029 ◽

1969 ◽

Vol 61 (1_Suppl) ◽

pp. S29

Author(s):

Pierre A. Desaulles ◽

René Maier ◽

Matthys Staehelin

Keyword(s):

Activity Relationship ◽

Structure Activity ◽

Relationship Of

The selective 5-HT2A receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH

Biochemical Pharmacology ◽

10.1016/j.bcp.2020.113979 ◽

2020 ◽

Vol 177 ◽

pp. 113979 ◽

Cited By ~ 3

Author(s):

Anders A. Jensen ◽

Adam L. Halberstadt ◽

Emil Märcher-Rørsted ◽

Anna U. Odland ◽

Muhammad Chatha ◽

...

Keyword(s):

Receptor Agonist ◽

Ex Vivo ◽

Activity Relationship ◽

Binding Characteristics ◽

Fluoro-benzimidazole derivatives to cure Alzheimer’s disease: In-silico studies, synthesis, structure-activity relationship and in vivo evaluation for β secretase enzyme inhibition

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.102936 ◽

2019 ◽

Vol 88 ◽

pp. 102936 ◽

Cited By ~ 1

Author(s):

Sayyad Ali ◽

Muhammad Hassham Hassan Bin Asad ◽

Soham Maity ◽

Wahid Zada ◽

Albert A. Rizvanov ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Enzyme Inhibition ◽

In Silico ◽

Activity Relationship ◽

Benzimidazole Derivatives ◽

In Vivo Evaluation ◽

Structure Activity ◽

In Silico Studies

Radiochemical Investigations of99mTc−N3S-X-BBN[7−14]NH2: An in Vitro/in Vivo Structure−Activity Relationship Study Where X = 0-, 3-, 5-, 8-, and 11-Carbon Tethering Moieties

Bioconjugate Chemistry ◽

10.1021/bc020034r ◽

2003 ◽

Vol 14 (1) ◽

pp. 93-102 ◽

Cited By ~ 63

Author(s):

C. Jeffrey Smith ◽

Hariprasad Gali ◽

Gary L. Sieckman ◽

Chris Higginbotham ◽

Wynn A. Volkert ◽

...

Keyword(s):

Activity Relationship ◽

Structure Activity ◽

Relationship Study

Fungal metabolite ophiobolin A as a promising anti-glioma agent: In vivo evaluation, structure–activity relationship and unique pyrrolylation of primary amines

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2015.08.066 ◽

2015 ◽

Vol 25 (20) ◽

pp. 4544-4548 ◽

Cited By ~ 19

Author(s):

Ramesh Dasari ◽

Marco Masi ◽

Romana Lisy ◽

Marlène Ferdérin ◽

Lance R. English ◽

...

Keyword(s):

Activity Relationship ◽

Primary Amines ◽

Fungal Metabolite ◽

In Vivo Evaluation ◽

Discovery and Structure−Activity Relationship of Antagonists of B-Cell Lymphoma 2 Family Proteins with Chemopotentiation Activity in Vitro and in Vivo

Journal of Medicinal Chemistry ◽

10.1021/jm050754u ◽

2006 ◽

Vol 49 (3) ◽

pp. 1165-1181 ◽

Cited By ~ 94

Author(s):

Michael D. Wendt ◽

Wang Shen ◽

Aaron Kunzer ◽

William J. McClellan ◽

Milan Bruncko ◽

...

Keyword(s):

B Cell ◽

Cell Lymphoma ◽

B Cell Lymphoma ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of