Polyhedral Oligomeric Silsesquioxane Nanocomposite Thin Films via Layer-by-layer Electrostatic Self-Assembly

2006 ◽  
Vol 18 (16) ◽  
pp. 3726-3732 ◽  
Author(s):  
Guojun Wu ◽  
Zhaohui Su
2009 ◽  
Vol 9 (3) ◽  
pp. 1839-1843 ◽  
Author(s):  
Ying-Ling Liu ◽  
Chuan-Shun Liu ◽  
Wei-Hong Chen ◽  
Shi-Yi Chen ◽  
Ko-Shung Wang ◽  
...  

2002 ◽  
Author(s):  
Brent Viers ◽  
Shawn Phillips ◽  
Timothy Haddad ◽  
Alan Esker ◽  
Joe Polidan

Pharmaceutics ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1208
Author(s):  
Narsimha Mamidi ◽  
Ramiro Velasco Delgadillo ◽  
Aldo Gonzáles Ortiz ◽  
Enrique Barrera

Herein, poly (N-(4-aminophenyl) methacrylamide))-carbon nano-onions (PAPMA-CNOs = f-CNOs) and anilinated-poly (ether ether ketone) (AN-PEEK) have synthesized, and AN-PEEK/f-CNOs composite thin films were primed via layer-by-layer (LbL) self-assembly for stimuli-responsive drug release. The obtained thin films exhibited pH-responsive drug release in a controlled manner; pH 4.5 = 99.2% and pH 6.5 = 59.3% of doxorubicin (DOX) release was observed over 15 days. Supramolecular π-π stacking interactions between f-CNOs and DOX played a critical role in controlling drug release from thin films. Cell viability was studied with human osteoblast cells and augmented viability was perceived. Moreover, the thin films presented 891.4 ± 8.2 MPa of the tensile strength (σult), 43.2 ± 1.1 GPa of Young’s modulus (E), and 164.5 ± 1.7 Jg−1 of toughness (K). Quantitative scrutiny revealed that the well-ordered aligned nanofibers provide critical interphase, and this could be responsible for augmented tensile properties. Nonetheless, a pH-responsive and mechanically robust biocompatible thin-film system may show potential applications in the biomedical field.


Langmuir ◽  
2017 ◽  
Vol 33 (46) ◽  
pp. 13332-13342 ◽  
Author(s):  
Huiwen He ◽  
Si Chen ◽  
Xiaoqian Tong ◽  
Zhihang An ◽  
Meng Ma ◽  
...  

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