Electrochemical Aptasensor Based on Proximity-Dependent Surface Hybridization Assay for Single-Step, Reusable, Sensitive Protein Detection

2007 ◽  
Vol 129 (50) ◽  
pp. 15448-15449 ◽  
Author(s):  
Yan-Li Zhang ◽  
Yong Huang ◽  
Jian-Hui Jiang ◽  
Guo-Li Shen ◽  
Ru-Qin Yu
2009 ◽  
Vol 21 (11) ◽  
pp. 1327-1333 ◽  
Author(s):  
Yan-Li Zhang ◽  
Peng-Fei Pang ◽  
Jian-Hui Jiang ◽  
Guo-Li Shen ◽  
Ru-Qin Yu

2018 ◽  
Vol 66 (38) ◽  
pp. 10106-10112 ◽  
Author(s):  
Xinai Zhang ◽  
Chenyong Huang ◽  
Yanjuan Jiang ◽  
Yuxiang Jiang ◽  
Jianzhong Shen ◽  
...  

2013 ◽  
Vol 753-755 ◽  
pp. 2113-2116 ◽  
Author(s):  
Han Feng Cui ◽  
Hao Fan ◽  
Yan Lin

A sensitive electrochemical aptasensor for detection of thrombin based on target protein-induced strand displacement is presented. For this proposed aptasensor, dsDNA which is from immobilized probe DNA (IP) which has a hybridized with aptamer(Apt) initially was immobilized on the Au electrode through thiol group of IP,while a DNA labeled with PdS nanoparticles was used as a detection probe (DP-PdS). When Au electrode immersed into solution which contain target protein and DP-PdS, the aptamer preferred to form G-quarter structure with the present target protein and dsDNA was released into immobilized probe DNA (IP) which could be hybridized with DP-PdS. After dissolving PdS from electrode, a mercury-film electrode was used for electrochemical detection of these Pd2+ ions which offered excellent electrochemical signal transduction. Detection of thrombin was specific without being affected by the coexistence of other proteins such as BSA and lysozyme, and as low as 2.3×10-11 mol/L of thrombin was detected.


2017 ◽  
Vol 5 (27) ◽  
pp. 5362-5372 ◽  
Author(s):  
Hong-Lei Shuai ◽  
Xu Wu ◽  
Ke-Jing Huang

In this work, we report the development of an ultrasensitive sandwich-type electrochemical aptasensor for protein detection.


2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Galina S. Zamay ◽  
Tatiana N. Zamay ◽  
Vasilii A. Kolovskii ◽  
Alexandr V. Shabanov ◽  
Yury E. Glazyrin ◽  
...  

2012 ◽  
Vol 36 (1) ◽  
pp. 12-17 ◽  
Author(s):  
Wei Cheng ◽  
Shijia Ding ◽  
Qing Li ◽  
Tianxiao Yu ◽  
Yibin Yin ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document