Microphotoelectrochemical Surface-Enhanced Raman Spectroscopy: Toward Bridging Hot-Electron Transfer with a Molecular Reaction

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pp. 8483-8489 ◽  
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Wei Wang ◽  
Hong-Yu Guo ◽  
Chao Zhan ◽  
Sai Duan ◽  
...  
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Hong-Jia Wang ◽  
Hua Zhang ◽  
Zhong-Qun Tian ◽  
Jian-Feng Li

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pp. 825-827 ◽  
Author(s):  
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K.A. Bunding Lee ◽  
R.A. Uphaus ◽  
T.M. Cotton

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Vol 128 (17) ◽  
pp. 173105
Author(s):  
Hui-Shu Feng ◽  
Fan Dong ◽  
Hai-Sheng Su ◽  
Matthew M. Sartin ◽  
Bin Ren

ChemSusChem ◽  
2013 ◽  
Vol 6 (3) ◽  
pp. 487-492 ◽  
Author(s):  
Hoang K. Ly ◽  
Falk Harnisch ◽  
Siang-Fu Hong ◽  
Uwe Schröder ◽  
Peter Hildebrandt ◽  
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Yanfei Shen ◽  
Takashi Nakanishi ◽  
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Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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