Detection of Opioids on Mail/Packages Using Open Port Interface Mass Spectrometry (OPI-MS)

2020 ◽  
Vol 31 (11) ◽  
pp. 2370-2378
Author(s):  
Haidy Metwally ◽  
Prashant Agrawal ◽  
Rachael Smith ◽  
Chang Liu ◽  
Yves LeBlanc ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Open Port

scholarly journals Application of 3D printed tools for customized open port probe-electrospray mass spectrometry

Talanta ◽  
2020 ◽  
Vol 215 ◽  
pp. 120894 ◽  
Author(s):  
Piotr Sosnowski ◽  
Gérard Hopfgartner
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry ◽  
3D Printed ◽  
Open Port

scholarly journals Ultra-High-Throughput Acoustic Droplet Ejection-Open Port Interface-Mass Spectrometry for Parallel Medicinal Chemistry

2020 ◽  
Vol 11 (6) ◽  
pp. 1101-1110 ◽  
Author(s):  
Kenneth J. DiRico ◽  
Wenyi Hua ◽  
Chang Liu ◽  
Joseph W. Tucker ◽  
Anokha S. Ratnayake ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Throughput ◽  
Medicinal Chemistry ◽  
Droplet Ejection ◽  
Open Port

Open port sampling interface mass spectrometry of wipe-based explosives, oxidizers, and narcotics for trace contraband detection

2021 ◽  
Author(s):  
Thomas P Forbes ◽  
Jeffrey Lawrence ◽  
Changtong Hao ◽  
Greg Gillen
Keyword(s):  
Mass Spectrometry ◽  
Law Enforcement ◽  
Physicochemical Properties ◽  
Homeland Security ◽  
Rapid Screening ◽  
Organic P ◽  
Sampling Interface ◽  
Open Port

Rapid screening for chemical traces of explosives and narcotics is widely used to support homeland security and law enforcement. These target compounds span a range of physicochemical properties from organic...

scholarly journals Open Port Probe Sampling Interface for the Direct Coupling of Biocompatible Solid-Phase Microextraction to Atmospheric Pressure Ionization Mass Spectrometry

2017 ◽  
Vol 89 (7) ◽  
pp. 3805-3809 ◽  
Author(s):  
Germán Augusto Gómez-Ríos ◽  
Chang Liu ◽  
Marcos Tascon ◽  
Nathaly Reyes-Garcés ◽  
Don W. Arnold ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Atmospheric Pressure ◽  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Atmospheric Pressure Ionization ◽  
Sampling Interface ◽  
Pressure Ionization Mass Spectrometry ◽  
Open Port

scholarly journals Ultrahigh-Throughput ESI-MS: Sampling Pushed to Six Samples per Second by Acoustic Ejection Mass Spectrometry

2020 ◽  
Author(s):  
Tim Häbe ◽  
Chang Liu ◽  
Tom Covey ◽  
Roman P. Simon ◽  
Wolfgang Reindl ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Enzyme Assay ◽  
Sampling Rate ◽  
Internal Standard ◽  
Stress Tests ◽  
Esi Ms ◽  
Droplet Ejection ◽  
Signal Suppression ◽  
Dog Plasma ◽  
Open Port

<div> <p> We present an acoustic ejection mass spectrometry (AEMS) setup for ESI-MS based sample </p><p> injection at a sampling rate faster than current ESI and MALDI techniques. A modified acoustic </p><p> droplet ejection system was combined with an open port interface and a modified ESI source. To </p><p> simulate applications of drug metabolism and pharmacokinetics analysis and high-throughput </p><p> screening campaigns, two stress tests were performed regarding ion suppression and system </p><p> endurance in combination with minor sample preparation. Maximum sampling rate was 6 Hz for </p><p> dextromethorphan and d3-dextrorphan (each 100 nM) for 1152 injections in 63 s at FWHM of </p><p> 105 ms and %RSD of 7.7%/7.5% without internal standard correction. Enzyme assay buffer and </p><p> crude dog plasma caused signal suppression of 51%/73% at %RSD of 5.7%/6.7% (n = 120) and </p><p> stable OPI performance during 1100 injections. An endurance buffer revealed minor OPI pollution </p><p> and constant signals for >25.000 injections (%RSD = 8.5%, n = 10,557). </p></div>

scholarly journals Combined Falling Drop/Open Port Sampling Interface System for Automated Flow Injection Mass Spectrometry

2017 ◽  
Vol 89 (22) ◽  
pp. 12578-12586 ◽  
Author(s):  
Gary J. Van Berkel ◽  
Vilmos Kertesz ◽  
Matt Orcutt ◽  
Adam Bentley ◽  
Jim Glick ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Flow Injection ◽  
Interface System ◽  
Sampling Interface ◽  
Open Port

scholarly journals Fast quantitation of opioid isomers in human plasma by differential mobility spectrometry/mass spectrometry via SPME/open-port probe sampling interface

2017 ◽  
Vol 991 ◽  
pp. 89-94 ◽  
Author(s):  
Chang Liu ◽  
Germán Augusto Gómez-Ríos ◽  
Bradley B. Schneider ◽  
J.C.Yves Le Blanc ◽  
Nathaly Reyes-Garcés ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Human Plasma ◽  
Differential Mobility Spectrometry ◽  
Differential Mobility ◽  
Sampling Interface ◽  
Open Port

Fluid Dynamics of the Open Port Interface for High-Speed Nanoliter Volume Sampling Mass Spectrometry

2021 ◽  
Author(s):  
Chang Liu ◽  
Gary J. Van Berkel ◽  
Peter Kovarik ◽  
J. Blair Perot ◽  
Venkatesh Inguva ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Mass Spectrometry ◽  
High Speed ◽  
Open Port
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