Rapid Characterization of Drugs in Biological Fluid and Seized Material Using Thermal-Assisted Carbon Fiber Ionization Mass Spectrometry

2021 ◽  
Vol 32 (4) ◽  
pp. 969-976
Author(s):  
Junbo Zhao ◽  
Hui Yan ◽  
Yan Shi ◽  
Baohua Sheng ◽  
Ping Xiang
Keyword(s):  
Mass Spectrometry ◽  
Carbon Fiber ◽  
Biological Fluid ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Rapid Characterization

scholarly journals Exploration of Rapid Evaporative-Ionization Mass Spectrometry as a Shotgun Approach for the Comprehensive Characterization of Kigelia Africana (Lam) Benth. Fruit

Molecules ◽  
2020 ◽  
Vol 25 (4) ◽  
pp. 962 ◽  
Author(s):  
Katia Arena ◽  
Francesca Rigano ◽  
Domenica Mangraviti ◽  
Francesco Cacciola ◽  
Francesco Occhiuto ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Bacterial Infections ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Sampling Device ◽  
Inflammatory Processes ◽  
Rapid Characterization ◽  
Application Fields ◽  
Shotgun Approach

Rapid evaporative-ionization mass spectrometry (REIMS) coupled with an electroknife as a sampling device was recently employed in many application fields to obtain a rapid characterization of different samples without any need for extraction or cleanup procedures. In the present research, REIMS was used to obtain a metabolic profiling of the Kigelia africana fruit, thus extending the applicability of such a technique to the investigation of phytochemical constituents. In particular, the advantages of REIMS linked to a typical electrosurgical handpiece were applied for a comprehensive screening of this botanical species, by exploiting the mass accuracy and tandem MS capabilities of a quadrupole-time of flight analyzer. Then, 78 biomolecules were positively identified, including phenols, fatty acids and phospholipids. In the last decade, Kigelia africana (Lam.) Benth. fruit has attracted special interest for its drug-like properties, e.g., its use for infertility treatments and as anti-tumor agent, as well as against fungal and bacterial infections, diabetes, and inflammatory processes. Many of these properties are currently correlated to the presence of phenolic compounds, also detected in the present study, while the native lipid composition is here reported for the first time and could open new directions in the evaluation of therapeutic activity.

Characterization of different decomposition stages of biowaste using FT-IR spectroscopy and pyrolysis-field ionization mass spectrometry

2005 ◽  
Vol 16 (1) ◽  
pp. 67-79 ◽  
Author(s):  
Ena Smidt ◽  
Kai-uwe Eckhardt ◽  
Peter Lechner ◽  
Hans-rolf Schulten ◽  
Peter Leinweber
Keyword(s):  
Mass Spectrometry ◽  
Ir Spectroscopy ◽  
Ionization Mass Spectrometry ◽  
Field Ionization ◽  
Ionization Mass ◽  
Ft Ir ◽  
Decomposition Stages ◽  
Ft Ir Spectroscopy
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