Investigation of Fragmentation Pathways of Fentanyl Analogues and Novel Synthetic Opioids by Electron Ionization High-Resolution Mass Spectrometry and Electrospray Ionization High-Resolution Tandem Mass Spectrometry

2020 ◽  
Vol 31 (2) ◽  
pp. 277-291 ◽  
Author(s):  
Qin Nan ◽  
Wu Hejian ◽  
Xiang Ping ◽  
Shen Baohua ◽  
Zhao Junbo ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Tandem Mass Spectrometry ◽  
Electrospray Ionization ◽  
High Resolution Mass Spectrometry ◽  
Tandem Mass ◽  
Fragmentation Pathways ◽  
Fentanyl Analogues ◽  
Novel Synthetic Opioids ◽  
Resolution Mass

scholarly journals The Copper(II) Ions Solvent Extraction with a New Compound: 2,6-Bis(4-Methoxybenzoyl)-Diaminopyridine

Processes ◽  
2019 ◽  
Vol 7 (12) ◽  
pp. 954 ◽  
Author(s):  
Daria Bożejewicz ◽  
Katarzyna Witt ◽  
Małgorzata A. Kaczorowska ◽  
Borys Ośmiałowski
Keyword(s):  
Mass Spectrometry ◽  
Solvent Extraction ◽  
High Resolution ◽  
Stability Constant ◽  
Tandem Mass Spectrometry ◽  
High Resolution Mass Spectrometry ◽  
Chloroform Solution ◽  
Tandem Mass ◽  
The Stability ◽  
Resolution Mass

A new compound 2,6-bis(4-methoxybenzoyl)-diaminopyridine (L) was used as an extractant for copper(II) ion recovery in a solvent extraction conducted at a temperature of 25 °C. The best results (99% recovery of copper(II) ions) were obtained when the aqueous phase contained 0.001 mol/dm3 Cu(II) and 0.2 mol/dm3 NH3 (pH~5.8), while the organic phase was a 0.001 mol/dm3 chloroform solution of 2,6-bis(4-methoxybenzoyl)-diaminopyridine. Spectrophotometry studies were used to determine the dissociation constant of the tested compound and determine the stability constant of the complex of subjected compound with copper(II) ions. The high-resolution mass spectrometry (HRMS) and higher energy collisional dissociation tandem mass spectrometry (HCD MS/MS) methods have been applied for the confirmation of the structure of 2,6-bis(4-methoxybenzoyl)-diaminopyridine and to determine its complexation with Cu(II) in solution.

Sign in / Sign up

Export Citation Format

Share Document