scholarly journals Structure−Activity Relationship Study of Prion Inhibition by 2-Aminopyridine-3,5-dicarbonitrile-Based Compounds:  Parallel Synthesis, Bioactivity, and in Vitro Pharmacokinetics.

2007 ◽  
Vol 50 (5) ◽  
pp. 1086-1086
Author(s):  
Barnaby C. H. May ◽  
Julie A. Zorn ◽  
Juanita Witkop ◽  
John Sherrill ◽  
Andrew C. Wallace ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Parallel Synthesis ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study

Radiochemical Investigations of99mTc−N3S-X-BBN[7−14]NH2:  An in Vitro/in Vivo Structure−Activity Relationship Study Where X = 0-, 3-, 5-, 8-, and 11-Carbon Tethering Moieties

2003 ◽  
Vol 14 (1) ◽  
pp. 93-102 ◽  
Author(s):  
C. Jeffrey Smith ◽  
Hariprasad Gali ◽  
Gary L. Sieckman ◽  
Chris Higginbotham ◽  
Wynn A. Volkert ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study

Synthesis of tyrosol glycosides and their structure–activity relationship study in biochemical assays and in human cells in vitro

2017 ◽  
Vol 280 ◽  
pp. S118
Author(s):  
Eva Horvathova ◽  
Eliska Galova ◽  
Andrea Sevcovicova ◽  
Martina Klapakova ◽  
Andrej Bohac ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Human Cells ◽  
Activity Relationship ◽  
Structure Activity ◽  
Biochemical Assays ◽  
Relationship Study

Synthesis and In Vitro Antimicrobial Activity of Medicinally Important Novel N-alkyl, N-aryl and Urea Derivatives of 1-benzhydryl Piperizine: A Structure-Activity Relationship Study

2009 ◽  
Vol 6 (2) ◽  
pp. 146-154
Author(s):  
Channapillekoppal Ananda Kumar ◽  
Karunakara Murthy ◽  
Marlinganadoddi Sadashiva ◽  
Mallappanahally Vinaya ◽  
Naraganahalli Thimmegowda ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Urea Derivatives ◽  
In Vitro Antimicrobial Activity ◽  
Structure Activity ◽  
Relationship Study ◽  
Derivatives Of

2-Substituted-5-Nitroheterocycles: In Vitro Anti-Helicobacter pylori Activity and Structure-Activity Relationship Study

2009 ◽  
Vol 5 (6) ◽  
pp. 529-534 ◽  
Author(s):  
Alireza Foroumadi ◽  
Maedeh Sorkhi ◽  
Mohammad Moshafi ◽  
Maliheh Safavi ◽  
Ardeshir Rineh ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study

Structure activity relationship study on the peptide hormone preptin, a novel bone-anabolic agent for the treatment of osteoporosis

2016 ◽  
Vol 14 (39) ◽  
pp. 9225-9238 ◽  
Author(s):  
Zaid Amso ◽  
Renata Kowalczyk ◽  
Maureen Watson ◽  
Young-Eun Park ◽  
Karen E. Callon ◽  
...  
Keyword(s):  
Peptide Hormone ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Treatment Of Osteoporosis ◽  
Anabolic Agent ◽  
Structure Activity ◽  
Relationship Study ◽  
Matrix Mineralisation ◽  
Rat Osteoblasts

Replacement of serine at position 3 of preptin (1-16) with alanine increased the proliferation and matrix mineralisation of foetal cultures of primary rat osteoblasts in vitro.

Structure–activity relationship study of dendritic polyglycerolamines for efficient siRNA transfection

RSC Advances ◽  
2015 ◽  
Vol 5 (96) ◽  
pp. 78760-78770 ◽  
Author(s):  
Fatemeh Sheikhi Mehrabadi ◽  
Ole Hirsch ◽  
Reiner Zeisig ◽  
Paola Posocco ◽  
Erik Laurini ◽  
...  
Keyword(s):  
In Silico ◽  
Gene Transfection ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Sirna Transfection ◽  
Structure Activity ◽  
Relationship Study

Structure–activity relationship studies were performed through in vitro, in silico, and in vivo analysis in order to evaluate the gene transfection potential of dendritic polyglycerolamines with different amine loadings.

Structure-Activity Relationship Study of 16 a-Thiocamptothecins: an Integrated In Vitro and In Silico Approach

ChemMedChem ◽  
2010 ◽  
Vol 5 (12) ◽  
pp. 2006-2015 ◽  
Author(s):  
Cristian Samorì ◽  
Giovanni L. Beretta ◽  
Greta Varchi ◽  
Andrea Guerrini ◽  
Simone DiemspMicco ◽  
...  
Keyword(s):  
In Silico ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study
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