Discovery of Aminobenzyloxyarylamides as κ Opioid Receptor Selective Antagonists: Application to Preclinical Development of a κ Opioid Receptor Antagonist Receptor Occupancy Tracer

2011 ◽  
Vol 54 (23) ◽  
pp. 8000-8012 ◽  
Author(s):  
Charles H. Mitch ◽  
Steven J. Quimby ◽  
Nuria Diaz ◽  
Concepcion Pedregal ◽  
Marta G. de la Torre ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Opioid Receptor ◽  
Receptor Occupancy ◽  
Preclinical Development ◽  
Opioid Receptor Antagonist ◽  
Selective Antagonists

scholarly journals Samidorphan, an opioid receptor antagonist, attenuates drug-induced increases in extracellular dopamine concentrations and drug self-administration in male Wistar rats

2021 ◽  
pp. 173157
Author(s):  
Jacobi I. Cunningham ◽  
Mark S. Todtenkopf ◽  
Reginald L. Dean ◽  
Marc R. Azar ◽  
George F. Koob ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Opioid Receptor ◽  
Wistar Rats ◽  
Self Administration ◽  
Drug Induced ◽  
Opioid Receptor Antagonist ◽  
Extracellular Dopamine ◽  
Male Wistar Rats

Naloxonazine, a specific mu-opioid receptor antagonist, attenuates the increment of locomotor activity induced by acute methamphetamine in mice

2012 ◽  
Vol 212 (1) ◽  
pp. 61-65 ◽  
Author(s):  
Chih-Cheng Chien ◽  
Yih-Jing Lee ◽  
Lir-Wan Fan ◽  
Ing-Kang Ho ◽  
Lu-Tai Tien
Keyword(s):  
Locomotor Activity ◽  
Receptor Antagonist ◽  
Opioid Receptor ◽  
Mu Opioid Receptor ◽  
Mu Opioid ◽  
Opioid Receptor Antagonist

Naltrindole-5'-isothiocyanate: a nonequilibrium, highly selective .delta.-opioid receptor antagonist

1990 ◽  
Vol 33 (6) ◽  
pp. 1547-1548 ◽  
Author(s):  
P. S. Portoghese ◽  
M. Sultana ◽  
A. E. Takemori
Keyword(s):  
Receptor Antagonist ◽  
Opioid Receptor ◽  
Delta Opioid Receptor ◽  
Opioid Receptor Antagonist

Effects of Naldemedine, a Peripherally Acting μ-Opioid Receptor Antagonist, on Inhibition of Large Intestinal Transit Induced by Morphine in Rodent Models

2017 ◽  
Vol 152 (5) ◽  
pp. S508
Author(s):  
Toshiyuki Kanemasa ◽  
Hiroko Ono ◽  
Atsushi Nakamura ◽  
Yasuhidse Morioka ◽  
Minoru Hasegawa
Keyword(s):  
Receptor Antagonist ◽  
Opioid Receptor ◽  
Intestinal Transit ◽  
Rodent Models ◽  
Opioid Receptor Antagonist ◽  
Μ Opioid Receptor

Alvimopan, a peripherally acting mu-opioid receptor antagonist, compared with placebo in postoperative ileus after major abdominal surgery

2005 ◽  
Vol 20 (1) ◽  
pp. 64-70 ◽  
Author(s):  
E. R. Viscusi ◽  
S. Goldstein ◽  
T. Witkowski ◽  
A. Andonakakis ◽  
R. Jan ◽  
...  
Keyword(s):  
Abdominal Surgery ◽  
Receptor Antagonist ◽  
Opioid Receptor ◽  
Postoperative Ileus ◽  
Mu Opioid Receptor ◽  
Major Abdominal Surgery ◽  
Mu Opioid ◽  
Opioid Receptor Antagonist
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