Structural Study of Acidic Phospholipid−Basic Homopolypeptide Complexes by31P and13C Solid-State NMR Chemical Shifts

1998 ◽  
Vol 102 (17) ◽  
pp. 3073-3076 ◽  
Author(s):  
Daisuke Sato ◽  
Naoki Asakawa ◽  
Minoru Sakurai ◽  
Yoshio Inoue
Keyword(s):  
Solid State ◽  
Structural Study ◽  
Solid State Nmr ◽  
Chemical Shifts ◽  
Nmr Chemical Shifts ◽  
Acidic Phospholipid

scholarly journals Inside Cover: Natural Abundance 15 N and 13 C Solid-State NMR Chemical Shifts: High Sensitivity Probes of the Halogen Bond Geometry (Chem. Eur. J. 47/2016)

2016 ◽  
Vol 22 (47) ◽  
pp. 16694-16694 ◽  
Author(s):  
Paolo Cerreia Vioglio ◽  
Luca Catalano ◽  
Vera Vasylyeva ◽  
Carlo Nervi ◽  
Michele R. Chierotti ◽  
...  
Keyword(s):  
Solid State ◽  
Solid State Nmr ◽  
Halogen Bond ◽  
Chemical Shifts ◽  
High Sensitivity ◽  
Natural Abundance ◽  
Nmr Chemical Shifts

scholarly journals NMR chemical shifts of urea loaded copper benzoate. A joint solid-state NMR and DFT study

2019 ◽  
Vol 101 ◽  
pp. 31-37 ◽  
Author(s):  
Zhipeng Ke ◽  
Lauren E. Jamieson ◽  
Daniel M. Dawson ◽  
Sharon E. Ashbrook ◽  
Michael Bühl
Keyword(s):  
Solid State ◽  
Solid State Nmr ◽  
Chemical Shifts ◽  
Dft Study ◽  
Nmr Chemical Shifts

Solid State NMR Chemical Shifts of Chalcogenides and Pnictides

1993 ◽  
pp. 49-73 ◽  
Author(s):  
Hellmut Eckert ◽  
Kelly Moran ◽  
Deanna Franke ◽  
Christopher Hudalla
Keyword(s):  
Solid State ◽  
Solid State Nmr ◽  
Chemical Shifts ◽  
Nmr Chemical Shifts

Improving the accuracy of solid-state nuclear magnetic resonance chemical shift prediction with a simple molecular correction

2019 ◽  
Vol 21 (27) ◽  
pp. 14992-15000 ◽  
Author(s):  
Martin Dračínský ◽  
Pablo Unzueta ◽  
Gregory J. O. Beran
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Solid State ◽  
Magnetic Resonance ◽  
Chemical Shift ◽  
Solid State Nmr ◽  
Chemical Shifts ◽  
Chemical Shift Prediction ◽  
Nmr Chemical Shifts ◽  
Nuclear Magnetic

A simple molecular correction improves significantly the accuracy of predictions of solid-state NMR chemical shifts.

scholarly journals Natural Abundance15N and13C Solid-State NMR Chemical Shifts: High Sensitivity Probes of the Halogen Bond Geometry

2016 ◽  
Vol 22 (47) ◽  
pp. 16819-16828 ◽  
Author(s):  
Paolo Cerreia Vioglio ◽  
Luca Catalano ◽  
Vera Vasylyeva ◽  
Carlo Nervi ◽  
Michele R. Chierotti ◽  
...  
Keyword(s):  
Solid State ◽  
Solid State Nmr ◽  
Halogen Bond ◽  
Chemical Shifts ◽  
High Sensitivity ◽  
Nmr Chemical Shifts

scholarly journals Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR

eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Simon Erlendsson ◽  
Kamil Gotfryd ◽  
Flemming Hofmann Larsen ◽  
Jonas Sigurd Mortensen ◽  
Michel-Andreas Geiger ◽  
...  
Keyword(s):  
Solid State ◽  
Binding Site ◽  
Solid State Nmr ◽  
Chemical Shifts ◽  
Substrate Binding ◽  
Experimental Conditions ◽  
Specific Chemical ◽  
Sodium Dependent ◽  
Number Of Binding Sites ◽  
Neurotransmitter:Sodium Symporter

The Neurotransmitter:Sodium Symporters (NSSs) represent an important class of proteins mediating sodium-dependent uptake of neurotransmitters from the extracellular space. The substrate binding stoichiometry of the bacterial NSS protein, LeuT, and thus the principal transport mechanism, has been heavily debated. Here we used solid state NMR to specifically characterize the bound leucine ligand and probe the number of binding sites in LeuT. We were able to produce high-quality NMR spectra of substrate bound to microcrystalline LeuT samples and identify one set of sodium-dependent substrate-specific chemical shifts. Furthermore, our data show that the binding site mutants F253A and L400S, which probe the major S1 binding site and the proposed S2 binding site, respectively, retain sodium-dependent substrate binding in the S1 site similar to the wild-type protein. We conclude that under our experimental conditions there is only one detectable leucine molecule bound to LeuT.

scholarly journals 14N1H HMQC Solid-State NMR as a Powerful Tool to Study Amorphous Formulations – an Exemplary Study of Paclitaxel Loaded Polymer Micelles

2020 ◽  
Author(s):  
Marvin Grüne ◽  
Robert Luxenhofer ◽  
Dinu Iuga ◽  
Steven P. Brown ◽  
Ann-Christin Pöppler
Keyword(s):  
Solid State ◽  
Solid State Nmr ◽  
Chemical Shifts ◽  
Mas Nmr ◽  
Cancer Drug ◽  
Polymer Micelles ◽  
Promising Tool ◽  
Nmr Characterization

We present <sup>14</sup>N-<sup>1</sup>H HMQC MAS NMR experiments in the solid state as a promising tool to study amorphous formulations. Poly(2-oxazoline) based polymer micelles loaded with different amounts of the cancer drug paclitaxel serve to highlight the possibilities offered by these experiments: While the very similar <sup>15</sup>N chemical shifts hamper a solid-state NMR characterization based on this nucleus, <sup>14</sup>N is a very versatile alternative. <sup>14</sup>N-<sup>1</sup>H HMQC experiments yield well-separated signals, which are spread over a large ppm range, provide information on the symmetry of the nitrogen environment and probe <sup>14</sup>N-<sup>1</sup>H through-space proximities.

Two-dimensional solid-state NMR studies of crystalline poly(ethylene oxide): Conformations and chemical shifts

Polymer ◽  
2005 ◽  
Vol 46 (25) ◽  
pp. 11737-11743 ◽  
Author(s):  
D.J. Harris ◽  
T.J. Bonagamba ◽  
M. Hong ◽  
K. Schmidt-Rohr
Keyword(s):  
Solid State ◽  
Ethylene Oxide ◽  
Solid State Nmr ◽  
Chemical Shifts ◽  
Two Dimensional ◽  
Nmr Studies ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene
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