Efficient in Vivo Gene Transfer by Intraperitoneal Injection of Plasmid DNA and Calcium Carbonate Microflowers in Mice

2012 ◽  
Vol 9 (7) ◽  
pp. 1962-1970 ◽  
Author(s):  
Shintaro Fumoto ◽  
Sayuri Nakajima ◽  
Toyoharu Mine ◽  
Naoki Yoshikawa ◽  
Takashi Kitahara ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Gene Transfer ◽  
Plasmid Dna ◽  
Intraperitoneal Injection ◽  
In Vivo Gene Transfer

HIGH EFFICIENCY TARGETED IN VIVO GENE TRANSFER TO KIDNEY TUMORS USING INTRAARTERIAL ADMINISTRATION OF PLASMID DNA IN COMPLEX WITH CATIONIC POLYLIPOSOME

1999 ◽  
pp. 142
Author(s):  
Woo-Chul Moon ◽  
Sam-Young Moon ◽  
Joon-Hyun Han ◽  
Hung-Jin Shim ◽  
Byung-Goo Kim
Keyword(s):  
Gene Transfer ◽  
Plasmid Dna ◽  
High Efficiency ◽  
Kidney Tumors ◽  
In Vivo Gene Transfer

In Vivo Gene Transfer and Expression in Rat Stomach by Submucosal Injection of Plasmid DNA

1996 ◽  
Vol 7 (5) ◽  
pp. 589-593 ◽  
Author(s):  
Tetsuo Takehara ◽  
Norio Hayashi ◽  
Masato Yamamoto ◽  
Yasuhide Miyamoto ◽  
Hideyuki Fusamoto ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Plasmid Dna ◽  
Rat Stomach ◽  
Submucosal Injection ◽  
In Vivo Gene Transfer

scholarly journals In vivo gene transfer using cetylated polyethylenimine.

2004 ◽  
Vol 51 (3) ◽  
pp. 693-702 ◽  
Author(s):  
Aleksander Sochanik ◽  
Tomasz Cichoń ◽  
Monika Makselon ◽  
Małgorzata Strózyk ◽  
Ryszard Smolarczyk ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Plasmid Dna ◽  
Dna Degradation ◽  
Dna Transfer ◽  
Luciferase Expression ◽  
Luciferase Gene ◽  
Amine Groups ◽  
In Vivo Gene Transfer

This report describes gene transfer in vitro as well as in vivo using cetylated low-molecular mass (600 Da) polyethylenimine (28% of amine groups substituted with cetyl moieties), termed CT-PEI. This compound is hydrophobic and has to be incorporated into liposomes in order to be suitable for gene transfer studies. Serum-induced plasmid DNA degradation assay demonstrated that CT-PEI-containing liposomal carriers could protect complexed DNA (probably via condensation). In vitro luciferase gene expression achieved using medium supplemented with 10% serum was comparable to that achieved in serum-reduced medium and was highest for CT-PEI/cholesterol liposomes, followed by CT-PEI/dioleoylphosphatidylcholine liposomes and PEI 600 Da (uncetylated) carrier. In vivo systemic transfer into mice was most efficient when liposome formulations contained CT-PEI and cholesterol. Higher luciferase expression was then observed in lungs than in liver. liposomes containing cetylated polyethylenimine and cholesterol are a suitable vehicle for investigating systemic plasmid DNA transfer into lungs.

In vivo gene transfer into the adult mammalian central nervous system by continuous injection of plasmid DNA–cationic liposome complex

1998 ◽  
Vol 780 (1) ◽  
pp. 119-128 ◽  
Author(s):  
Takashi Imaoka ◽  
Isao Date ◽  
Takashi Ohmoto ◽  
Tatsuji Yasuda ◽  
Masaaki Tsuda
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Gene Transfer ◽  
Plasmid Dna ◽  
Cationic Liposome ◽  
Mammalian Central Nervous System ◽  
Continuous Injection ◽  
In Vivo Gene Transfer

1860: Generation of Fluorescent Sperm by Use of in VIVO Gene Transfer to Hamster Testes

2007 ◽  
Vol 177 (4S) ◽  
pp. 617-618
Author(s):  
Hiraki Kubota ◽  
Kevin Coward ◽  
Olivia Hibbitt ◽  
Nilendran Prathalingam ◽  
William Holt ◽  
...  
Keyword(s):  
Gene Transfer ◽  
In Vivo Gene Transfer

Tissue-Targeted In Vivo Gene Transfer Coupled with Histone Deacetylase Inhibitor Depsipeptide (FK228) Enhances Adenoviral Infection in Rat Renal Cancer Allograft Model Systems

Urology ◽  
2007 ◽  
Vol 70 (6) ◽  
pp. 1230-1236 ◽  
Author(s):  
Minoru Kobayashi ◽  
Takashi Okada ◽  
Takashi Murakami ◽  
Keiya Ozawa ◽  
Eiji Kobayashi ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Histone Deacetylase ◽  
Renal Cancer ◽  
Histone Deacetylase Inhibitor ◽  
Model Systems ◽  
Adenoviral Infection ◽  
Deacetylase Inhibitor ◽  
In Vivo Gene Transfer

scholarly journals In-vivo gene transfer induces transgene expression in cells and secretions of the mouse cauda epididymis

2009 ◽  
Vol 15 (6) ◽  
pp. 355-361 ◽  
Author(s):  
P. Esponda ◽  
R. Carballada
Keyword(s):  
Gene Transfer ◽  
Transgene Expression ◽  
In Vivo Gene Transfer ◽  
In Cells

In vivo expression and antitumor activity of p53 gene transfer with naked plasmid DNA in an ovarian cancer xenograft model in nude mice

2006 ◽  
Vol 32 (5) ◽  
pp. 449-453 ◽  
Author(s):  
Pierre Collinet ◽  
Rodolphe Vereecque ◽  
Frédéric Sabban ◽  
Denis Vinatier ◽  
Eric Leblanc ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Gene Transfer ◽  
Antitumor Activity ◽  
Nude Mice ◽  
Plasmid Dna ◽  
Xenograft Model ◽  
P53 Gene ◽  
Naked Plasmid ◽  
Naked Plasmid Dna
Sign in / Sign up

Export Citation Format

Share Document