Physical Chemical Drug–Drug Interactions from Drug Discovery to Registration: New Opportunities for the Pharmaceutical Scientist To Impact Drug Development

2013 ◽  
Vol 10 (11) ◽  
pp. 3967-3969
Author(s):  
Joseph A. Ware ◽  
Gena Dalziel
Keyword(s):  
Drug Discovery ◽  
Drug Development ◽  
Drug Interactions ◽  
Physical Chemical ◽  
Pharmaceutical Scientist

scholarly journals How Can We Tie Drug Development Seeds to Clinical ?^|^mdash;For Succeeding in Drug Discovery by Academia^|^mdash;

2013 ◽  
Vol 133 (2) ◽  
pp. 181-182
Author(s):  
Taisuke Hojo ◽  
Masatoshi Narita
Keyword(s):  
Drug Discovery ◽  
Drug Development

scholarly journals An integrated dataset for in silico drug discovery

2010 ◽  
Vol 7 (3) ◽  
Author(s):  
Simon J Cockell ◽  
Jochen Weile ◽  
Phillip Lord ◽  
Claire Wipat ◽  
Dmytro Andriychenko ◽  
...  
Keyword(s):  
Systems Biology ◽  
Drug Discovery ◽  
Drug Development ◽  
Data Integration ◽  
In Silico ◽  
Drug Repositioning ◽  
Integrated Systems ◽  
Integration Platform ◽  
Treatment Indications ◽  
New Treatment

SummaryDrug development is expensive and prone to failure. It is potentially much less risky and expensive to reuse a drug developed for one condition for treating a second disease, than it is to develop an entirely new compound. Systematic approaches to drug repositioning are needed to increase throughput and find candidates more reliably. Here we address this need with an integrated systems biology dataset, developed using the Ondex data integration platform, for the in silico discovery of new drug repositioning candidates. We demonstrate that the information in this dataset allows known repositioning examples to be discovered. We also propose a means of automating the search for new treatment indications of existing compounds.

scholarly journals Predicting Drug-Drug Interactions for Premarket Drug Development Process: A Network Based Approach

2018 ◽  
Vol 11 (1) ◽  
pp. 1
Author(s):  
S. D. L. Gunawardena ◽  
A. R. Weerasinghe ◽  
M. W. A. C. R. Wijesinghe
Keyword(s):  
Drug Development ◽  
Drug Interactions ◽  
Development Process ◽  
Drug Development Process

Translational in vitro research: integrating 3D drug discovery and development processes into the drug development pipeline

2019 ◽  
Vol 24 (1) ◽  
pp. 26-30 ◽  
Author(s):  
Jens M. Kelm ◽  
Madhu Lal-Nag ◽  
Gurusingham Sitta Sittampalam ◽  
Marc Ferrer
Keyword(s):  
Drug Discovery ◽  
Drug Development ◽  
Drug Discovery And Development ◽  
Development Processes ◽  
Development Pipeline

FDA Public Meeting Report on “Drug Interactions With Hormonal Contraceptives: Public Health and Drug Development Implications”

2018 ◽  
Vol 58 (12) ◽  
pp. 1655-1665 ◽  
Author(s):  
Mohammad Akbar ◽  
Erin Berry-Bibee ◽  
Diana L. Blithe ◽  
Ruth S. Day ◽  
Alison Edelman ◽  
...  
Keyword(s):  
Public Health ◽  
Drug Development ◽  
Drug Interactions ◽  
Hormonal Contraceptives ◽  
Meeting Report ◽  
Public Meeting

New development and update on China Bioanalysis Forum

Bioanalysis ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 199-201
Author(s):  
Fan Jin ◽  
Daniel Tang ◽  
Kelly Dong ◽  
Dafang Zhong
Keyword(s):  
Drug Discovery ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Drug Development ◽  
Research And Development ◽  
Continuous Growth ◽  
Contract Research Organization ◽  
Drug Discovery And Development ◽  
Medicine Research ◽  
New Development

This article provides an update on new development of China Bioanalysis Forum (CBF). CBF became a member association of Chinese Pharmaceutical Association (CPA) at the end of 2019. The official ceremony and first scientific symposium were held in Shanghai on 18 September 2020. The president of Chinese Pharmaceutical Association and representatives from industry, Contract Research Organization (CRO), hospitals and academic institutes attended the ceremony. Seven experts in the field gave presentations on various topics including Drug Metabolism and Pharmacokinetics (DMPK) and bioanalytical support in drug discovery and development as well as experience in Traditional Chinese Medicine research. With the continuous growth of research and development in China, it is well acknowledged that bioanalysis provides critical support for new innovative medicines and generic drug development in the region.

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