The relationship of plasma glutamine to ammonium and of glycine to acid-base balance in propionic acidaemia

2003 ◽  
Vol 26 (1) ◽  
pp. 89-91 ◽  
Author(s):  
Z. N. Al-Hassnan ◽  
S. A. Boyadjiev ◽  
V. Praphanphoj ◽  
A. Hamosh ◽  
N. E. Braverman ◽  
...  
Keyword(s):  
Propionic Acidaemia ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance ◽  
Relationship Of ◽  
The Relationship

Effect of potassium depletion on cerebrospinal fluid bicarbonate homeostasis

1976 ◽  
Vol 231 (2) ◽  
pp. 579-587 ◽  
Author(s):  
EE Nattie ◽  
SM Tenney
Keyword(s):  
Potassium Depletion ◽  
Acid Base Balance ◽  
Acid Base ◽  
Arterial Pco2 ◽  
Mixed Acid ◽  
Base Balance ◽  
Upward Direction ◽  
Relationship Of ◽  
The Relationship ◽  
K Depletion

We have examined the effect of K depletion on CSF [HCO3-] homeostasis in awake rats. The relationship of CSF [HCO3-] to arterial [HCO3-] in metabolic acid-base disturbances is displaced is an upward direction and has a significantly increased slope in K-depleted vs. control rats (0.51 +/- 0.02 vs. 0.42 +/- 0.02). Results of partial K-repletion experiments, with peripheral acid-base balance held constant, suggest that the effect is K specific. The K-depleted animals also exhibit a wider (CSF-arterial) PCO2 difference than controls (11.1 vs. 8.4 mmHg). When CSF [HCO3-] is shown as a function of CSF PCO2 the data of K-depleted rats are no longer displaced when compared to controls but still have a significantly greater slope (1.21 +/- 0.23 vs. 0.89 +/- 0.08). This increased slope is interpreted to reflect enhanced HCO3- movement from blood to CSF at high arterial [HCO3-]. Analysis of our data and observations from the literature in conditions of mixed acid-base disturbances suggest that CSF [HCO3-] is determined by a) CSF PCO2 and b) the level of arterial [HCO3-] when the latter is greater than the normal CSF [HCO3-].

Calculation of physiological acid-base parameters in multicompartment systems with application to human blood

2003 ◽  
Vol 95 (6) ◽  
pp. 2333-2344 ◽  
Author(s):  
E. Wrenn Wooten
Keyword(s):  
Base Change ◽  
Strong Ion Difference ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Parameters ◽  
Present Formalism ◽  
Base Balance ◽  
Multicompartment Systems ◽  
Relationship Of ◽  
The Relationship

A general formalism for calculating parameters describing physiological acid-base balance in single compartments is extended to multicompartment systems and demonstrated for the multicompartment example of human whole blood. Expressions for total titratable base, strong ion difference, change in total titratable base, change in strong ion difference, and change in Van Slyke standard bicarbonate are derived, giving calculated values in agreement with experimental data. The equations for multicompartment systems are found to have the same mathematical interrelationships as those for single compartments, and the relationship of the present formalism to the traditional form of the Van Slyke equation is also demonstrated. The multicompartment model brings the strong ion difference theory to the same quantitative level as the base excess method.

scholarly journals pH-regulation: the role of the hepatorenal system

1987 ◽  
Vol 6 (3) ◽  
pp. 115-117
Author(s):  
M. J. Pitout ◽  
G. T. Willemse
Keyword(s):  
Ph Regulation ◽  
Buffer System ◽  
Urea Synthesis ◽  
Ph Homeostasis ◽  
Acid Base Balance ◽  
Bicarbonate Concentration ◽  
Acid Base ◽  
Base Balance ◽  
The Relationship

The regulation of the acid-base balance is generally regarded as a well entrenched area. However, a number of confusing views on pH-homeostasis, especially with reference to the relationship between the kidney and the ammonium buffer system, appear regularly in textbooks. One reason is that the correct stoichiometry of acid-base regulation is not mentioned. Recently the rote of the liver in pH regulation by controlling the bicarbonate concentration through urea synthesis is proposed. In this paper the role of the liver and kidneys as a team is discussed.

scholarly journals Importancia del equilibrio ácido-base en la salud a partir de la alimentación

Tequio ◽  
2019 ◽  
Vol 2 (6) ◽  
pp. 45-53
Author(s):  
Héctor Ulises Bernardino Hernández ◽  
Arturo Zapién Martínez
Keyword(s):  
Human Body ◽  
The Body ◽  
Acid Base Balance ◽  
Food And Nutrition ◽  
Optimal Health ◽  
Base Balance ◽  
Unbalanced Diet ◽  
Relationship Of ◽  
The Relationship ◽  
Multiple Health

Food and nutrition have become a topic of interest due to the multiple health problems related to diet that have developed in recent years. Eating correctly is not necessarily following a long list of prohibitions, it is only necessary to know which food can correctly fulfill the nutrients that the human body needs. The pH balance is fundamental to have an optimal health, because when there is an increase in acidity, the body activates different systems to protect healthy cells and tissues. However, an unbalanced diet causes an excessive acidity that the human body cannot neutralize, which alters the proper cell functioning. The present paper describes the relationship of the acid-base balance with nourishment and its possible effects on health

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