Transforming growth factor-β1 expression in early biopsy specimen predicts long-term graft function following pediatric renal transplantation

2001 ◽  
Vol 15 (3) ◽  
pp. 185-191 ◽  
Author(s):  
Takeshi Ishimura ◽  
Masato Fujisawa ◽  
Shuji Isotani ◽  
Akihiro Higuchi ◽  
Kazumoto Iijima ◽  
...  
2005 ◽  
Vol 25 (3_suppl) ◽  
pp. 15-17 ◽  
Author(s):  
Peter J. Margetts ◽  
Kook-Hwan Oh ◽  
Martin Kolb

We have provided evidence from adenovirus-mediated gene transfer to the peritoneum that transforming growth factor-β1 mimics many of the functional and structural changes in the peritoneum in patients on long-term peritoneal dialysis, including fibrosis, increased submesothelial thickness, angiogenesis, increased solute transport, and ultrafiltration dysfunction. We review several key properties of this important fibrogenic molecule.


2005 ◽  
Vol 173 (4S) ◽  
pp. 159-159
Author(s):  
Wun-Jae Kim ◽  
ChangYi Quan ◽  
Pil-Du Jeoung ◽  
Eun-Jung Kim ◽  
Ji-Yeon Kim ◽  
...  

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