Big data and personalized medicine: the role of pathology

AccessScience ◽  
2015 ◽  
AI & Society ◽  
2021 ◽  
Author(s):  
Antonio Carnevale ◽  
Emanuela A. Tangari ◽  
Andrea Iannone ◽  
Elena Sartini

2018 ◽  
Vol 127 (2) ◽  
pp. 72-78 ◽  
Author(s):  
Kelvin Young ◽  
Gilda da Cunha Santos ◽  
Paul Card ◽  
Natasha Leighl

Author(s):  
Shankargouda Patil ◽  
Barnali Majumdar ◽  
Kamran Habib Awan ◽  
Gargi S. Sarode ◽  
Sachin C. Sarode ◽  
...  

Biobanks provide a platform for innovative biomedical research and has improvised translational and personalized medicine to a great extent. Time 2009 published 10 ideas changing the world right now with biobanks on the list emphasizing its role in discovery and development of new therapeutic drugs. They form the cornerstone, providing resources for future investigations and biomarker discovery to understand the effects of genetic, environmental and lifestyle factors on human morbidity, mortality and health. The aim of this review paper is to understand the role of biobanking in cancer research, the challenges faced and strategies to overcome these, for long term and sustainable research in the field of oncology.


TECHNOLOGY ◽  
2018 ◽  
Vol 06 (03n04) ◽  
pp. 79-100 ◽  
Author(s):  
Paulina Krzyszczyk ◽  
Alison Acevedo ◽  
Erika J. Davidoff ◽  
Lauren M. Timmins ◽  
Ileana Marrero-Berrios ◽  
...  

Cancer is a devastating disease that takes the lives of hundreds of thousands of people every year. Due to disease heterogeneity, standard treatments, such as chemotherapy or radiation, are effective in only a subset of the patient population. Tumors can have different underlying genetic causes and may express different proteins in one patient versus another. This inherent variability of cancer lends itself to the growing field of precision and personalized medicine (PPM). There are many ongoing efforts to acquire PPM data in order to characterize molecular differences between tumors. Some PPM products are already available to link these differences to an effective drug. It is clear that PPM cancer treatments can result in immense patient benefits, and companies and regulatory agencies have begun to recognize this. However, broader changes to the healthcare and insurance systems must be addressed if PPM is to become part of standard cancer care.


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