A lens model: Potent metaphor to facilitate finely tuned patient assessments

1997 ◽  
Author(s):  
Ann W. Aukamp
2006 ◽  
Author(s):  
Sarah Miller ◽  
Alex Kirlik
Keyword(s):  

1997 ◽  
Author(s):  
Gregory L. Brake ◽  
Michael E. Doherty ◽  
Gernot D. Kleiter
Keyword(s):  

2008 ◽  
Vol 38 (2) ◽  
pp. 29
Author(s):  
MITCHEL L. ZOLER

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Zhen Li ◽  
Sumin Gu ◽  
Yumeng Quan ◽  
Kulandaiappan Varadaraj ◽  
Jean X. Jiang

AbstractCongenital cataracts are associated with gene mutations, yet the underlying mechanism remains largely unknown. Here we reported an embryonic chick lens model that closely recapitulates the process of cataract formation. We adopted dominant-negative site mutations that cause congenital cataracts, connexin, Cx50E48K, aquaporin 0, AQP0R33C, αA-crystallin, CRYAA R12C and R54C. The recombinant retroviruses containing these mutants were microinjected into the occlusive lumen of chick lenses at early embryonic development. Cx50E48K expression developed cataracts associated with disorganized nuclei and enlarged extracellular spaces. Expression of AQP0R33C resulted in cortical cataracts, enlarged extracellular spaces and distorted fiber cell organization. αA crystallin mutations distorted lens light transmission and increased crystalline protein aggregation. Together, retroviral expression of congenital mutant genes in embryonic chick lenses closely mimics characteristics of human congenital cataracts. This model will provide an effective, reliable in vivo system to investigate the development and underlying mechanism of cataracts and other genetic diseases.


2021 ◽  
pp. 103985622110061
Author(s):  
Jeffrey C L Looi ◽  
Stephen Allison ◽  
Stephen R Kisely ◽  
William Pring ◽  
Rebecca E Reay ◽  
...  

Objective: The Australian Federal government introduced new COVID-19-Psychiatrist-Medicare-Benefits-Schedule (MBS) telehealth-items to assist with providing private specialist care. We investigate private psychiatrists’ uptake of telehealth, and face-to-face consultations for April–September 2020 for the state of Victoria, which experienced two consecutive waves of COVID-19. We compare these to the same 6 months in 2019. Method: MBS-item-consultation data were extracted for video, telephone and face-to-face consultations with a psychiatrist for April–September 2020 and compared to face-to-face consultations in the same period of 2019 Victoria-wide, and for all of Australia. Results: Total Victorian psychiatry consultations (telehealth and face-to-face) rose by 19% in April–September 2020 compared to 2019, with telehealth comprising 73% of this total. Victoria’s increase in total psychiatry consultations was 5% higher than the all-Australian increase. Face-to-face consultations in April–September 2020 were only 46% of the comparative 2019 consultations. Consultations of less than 15 min duration (87% telephone and 13% video) tripled in April–September 2020, compared to the same period last year. Video consultations comprised 41% of total telehealth provision: these were used mainly for new patient assessments and longer consultations. Conclusions: During the pandemic, Victorian private psychiatrists used COVID-19-MBS-telehealth-items to substantially increase the number of total patient care consultations for 2020 compared to 2019.


2021 ◽  
Vol 42 (Supplement_1) ◽  
pp. S172-S173
Author(s):  
Lauren B Nosanov ◽  
Kaitlyn Libraro ◽  
Jamie Heffernan ◽  
Philip H Chang ◽  
Abraham Houng ◽  
...  

Abstract Introduction An institutional Burn Intensive Care Unit (ICU) Rounding Tool was implemented for both quality improvement data collection and trainee education. Forms are completed by trainee team members daily for all critically ill patients prior to teaching rounds. Gathered data are structured to facilitate evaluation of patient volume status, sepsis risk and ventilator management. The forms are then used to guide discussion among students, residents, mid-level providers, fellows, attending surgeons and other members of the multi-disciplinary rounding team. We conducted a series of interviews with trainees regarding their user experience to assess the tool’s educational utility. Methods A convenience sample of residents who had recently completed their Burn Surgery rotation were interviewed in a structured format. Questions focused on the form’s ease of use and comprehensibility. Emphasis was placed on the extent to which it stimulates learning while rounding. Additional feedback was sought for the purpose of improving the tool for continued use. Results Participants were post-graduate year one or two resident physicians training in General Surgery, Urology, Emergency Medicine or Anesthesia. Prior experience and comfort with ICU level care ranged from very little to moderate. All interviewees found the tool helpful in their patient assessments, though the current layout of the form was a frustration for many. Overall, they unanimously found the forms beneficial for preparation of patient presentations and felt that utilization during rounds facilitated learning. Conclusions Interviews with trainees on their burn surgery rotation demonstrate that implementation of an ICU Rounding Tool has provided educational benefit, particularly for those less experienced in intensive care. Feedback from this cohort will be used to improve the tool’s usability. Our next steps will include a more formal survey of all trainees involved since the inception of this project.


1998 ◽  
Vol 50 (1) ◽  
pp. 175-186
Author(s):  
Katsuaki Asano ◽  
Takeshi Fukuyama
Keyword(s):  

2005 ◽  
Vol 22 (2) ◽  
pp. 128-135 ◽  
Author(s):  
Brendon J. Brewer ◽  
Geraint F. Lewis

AbstractGravitational lensing can magnify a distant source, revealing structural detail which is normally unresolvable. Recovering this detail through an inversion of the influence of gravitational lensing, however, requires optimisation of not only lens parameters, but also of the surface brightness distribution of the source. This paper outlines a new approach to this inversion, utilising genetic algorithms to reconstruct the source profile. In this initial study, the effects of image degradation due to instrumental and atmospheric effects are neglected and it is assumed that the lens model is accurately known, but the genetic algorithm approach can be incorporated into more general optimisation techniques, allowing the optimisation of both the parameters for a lensing model and the surface brightness of the source.


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