The state of LGBQ affirmative therapy clinical research: A mixed-methods systematic synthesis.

2018 ◽  
Vol 5 (1) ◽  
pp. 82-98 ◽  
Author(s):  
Tiffany O'Shaughnessy ◽  
Zachary Speir
Keyword(s):  
Mixed Methods ◽  
Clinical Research ◽  
The State ◽  
Affirmative Therapy ◽  
Systematic Synthesis

Editors' note: The state of clinical research in neurology

Neurology ◽  
2018 ◽  
Vol 91 (21) ◽  
pp. 983.1-983
Author(s):  
James E. Siegler ◽  
Steven Galetta
Keyword(s):  
Clinical Research ◽  
The State

scholarly journals Adapting Coordinated Specialty Care in the Post-COVID-19 Era: Study Protocol for an Integrative Mixed-methods Study

2021 ◽  
Author(s):  
Sapana Patel ◽  
Iruma Bello ◽  
Leopoldo J. Cabassa ◽  
Ilana R. Nossel ◽  
Melanie M. Wall ◽  
...  
Keyword(s):  
New York ◽  
Mixed Methods ◽  
Service Utilization ◽  
New York State ◽  
Specialty Care ◽  
The State ◽  
Care Process ◽  
Model Adaptation ◽  
York State ◽  
State And Local

Abstract Background: Coordinated Specialty Care (CSC) programs provide evidence-based services for young people with a recent onset of a psychotic disorder. OnTrackNY is a nationally recognized model of CSC treatment in New York state. In 2019, OnTrackNY was awarded a hub within the Early Psychosis Intervention Network (EPINET) to advance its learning health care system (LHS). The OnTrackNY network is comprised of 23 CSC teams across New York state. OnTrack Central, an intermediary organization, provides training and implementation support to OnTrackNY teams. OnTrack Central coordinates a centralized data collection protocol for quality improvement and evaluation of program fidelity and a mechanism to support practice based-research. OnTrackNY sites’ breadth coupled with OnTrack Central oversight provides an opportunity to examine the impacts of the COVID-19 crisis in New York State. Methods: This project will examine the implications of modifications to service delivery within the OnTrackNY LHS during and after the COVID-19 crisis. We will use the Framework for Reporting Adaptations and Modifications-Enhanced (FRAME) to classify systematically, code, and analyze modifications to CSC services and ascertain their impact. We will utilize integrative mixed methods. Qualitative interviews with multi-level stakeholders (program participants, families, providers, team leaders, agency leaders, trainers (OnTrack Central), and decision-makers at the state and local levels) will be used to understand the process making decisions, information about modifications to CSC services, and their impact. Analysis of OnTrackNY program data will facilitate examining trends in team staffing and functioning, and participant service utilization and outcomes. Study findings will be summarized in a CSC Model Adaptation Guide, which will identify modifications as fidelity consistent or not, and their impact on service utilization and care outcomes. Discussion: A CSC Model Adaptation Guide will inform CSC programs, and the state and local mental health authorities to which they are accountable, regarding modifications to CSC services and the impact of these changes on care process, and participant service utilization and outcomes. The guide will also inform the development of tailored technical assistance that CSC programs may need within OnTrackNY, the EPINET network, and CSC programs nationally. Trial Registration: NCT04021719, July 16th, 2019.

Separatist Threat, Militarization and Voter Turnout: Exploring the Dynamics of the 2017 Governorship Election in Anambra State, Nigeria

2020 ◽  
Vol 55 (8) ◽  
pp. 1093-1107
Author(s):  
Peter O. Mbah ◽  
Thaddeus C. Nzeadibe ◽  
Chikodiri Nwangwu ◽  
Ambrose O. Iheanacho ◽  
Christopher Okonkwo Eze ◽  
...  
Keyword(s):  
Mixed Methods ◽  
Voter Turnout ◽  
Political Development ◽  
State Building ◽  
The State ◽  
Mixed Methods Approach ◽  
Anambra State ◽  
Political Exclusion ◽  
The Impact

Using the qual-dominant mixed methods approach, this study analysed the impact of the separatist threat and the militarization of elections on voter turnout during the 2017 governorship election in Anambra State, Nigeria. Findings indicate that perceived and real marginalization of the Igbo in Nigeria’s state-building is largely driving the neo-Biafra separatist threat to boycott elections in Anambra State. This does not only account for the state militarization of elections in order to guarantee security; it also inadvertently engendered fear among citizens, undermined voter turnout and exacerbated political exclusion. This study concludes that inclusive political development presents an opportunity for de-escalation of separatist threats, demilitarization of elections and enhancement of voter turnout in Nigeria.

Trials in thrombectomy for acute ischemic stroke: Describing the state of clinical research in the field

2021 ◽  
Vol 200 ◽  
pp. 106360
Author(s):  
Michael L. Martini ◽  
Sean N. Neifert ◽  
Jacques J. Lara-Reyna ◽  
William H. Shuman ◽  
Travis R. Ladner ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Clinical Research ◽  
Acute Ischemic Stroke ◽  
The State

The State of Stroke Clinical Research

2015 ◽  
Vol 15 (2) ◽  
pp. 6-7
Author(s):  
M. Cunningham ◽  
G. Hankey
Keyword(s):  
Clinical Research ◽  
The State

The Manipulation of the Boundary Layer

1938 ◽  
Vol 42 (333) ◽  
pp. 816-838 ◽  
Author(s):  
E. G. Richardson
Keyword(s):  
Boundary Layer ◽  
Turbulent Flow ◽  
Clinical Research ◽  
Opposite Effect ◽  
The State ◽  
The Past ◽  
Flow Round ◽  
State Of Affairs ◽  
Vexed Question

In this paper I have endeavoured to give an account of the various methods which have been employed in the past ten years to alter—for better or worse— the conditions in the boundary layer of a body in turbulent flow. I have refrained from speaking of “ control ” in reference to the-boundary layer, since in the minds of most people, this implies an amelioration of the flow and a reduction of drag. As will appear in what follows, some of the devices in which I and other experimenters have been concerned have just the opposite effect. Nevertheless, following the principles current in clinical research in medicine, I think we should find both what conditions will cause “ deterioration ”—if one may use the term—as well as those which will cause “ improvement ” of the flow round a body, if we are to progress in our knowledge of the state of affairs in the boundary layer. Working rather on my own in aerodynamics and not being committed to any rigid programme of research, I have followed my bent to explore unorthodox paths of experiment, the results of which I present with some diffidence in the hope that engineers may pursue them further with better equipment. I am afraid I have not gone deeply into the vexed question of the efficiency—in the engineering sense—of the devices I am going to describe to you, since, as a physicist that—nevertheless, important—aspect of the question does not interest me.

Author response: The state of clinical research in neurology

Neurology ◽  
2018 ◽  
Vol 91 (21) ◽  
pp. 984.1-984
Author(s):  
Deborah A. Hall
Keyword(s):  
Clinical Research ◽  
The State ◽  
Author Response

Abstract W P306: Identifying Stroke Researcher Challenges to Minority Inclusion in Clinical Research

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Heather Carman ◽  
Leigh Quarles ◽  
Lauren Southwick ◽  
Emma K Benn ◽  
Salina P Waddy ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Mixed Methods ◽  
Best Practices ◽  
Clinical Research ◽  
Focus Groups ◽  
Minority Recruitment ◽  
Mixed Methods Approach ◽  
Recruitment And Retention ◽  
Patient Reported ◽  
Key Informant

Background: Race-ethnic disparities exist in stroke incidence, recurrence and mortality. Minority participation in stroke clinical trials is staggeringly low. A significant literature describes patient-reported barriers to recruitment, but researcher barriers are not well documented. Aim: To assess stroke researcher best practices and challenges to minority inclusion in stroke trials. Methods: The National Initiative for Minority Involvement in Neurological Clinical Trials (NIMICT) uses a mixed methods approach including surveys, focus groups and key informant interviews to expand on understanding of minority recruitment and retention in stroke clinical trials. We designed and tested a 40-item survey based on literature review and used the results to inform semi-structured focus groups and key informant interviews among stroke clinical trial investigators (N=110). Results: Key stroke investigators, identified through the Princeton Conference, were invited via email to participate in the survey. Over 70% (n=93) responded: 68% White. Less than half (N=43) reported actively setting recruitment goals for minority inclusion. Only 37% (N=29) required cultural sensitivity training for recruitment staff. Over 80% reported treating adults unable to consent and were concerned about acute stroke time constraints negatively impacting patient/family participation decisions. Key themes from focus groups (N=17) included: 1) Role of government in defining valid minority sub analyses and enforcing existing inclusion guidelines; 2) Challenges unique to acute setting including consent in conditions of prognostic uncertainty; 3) Lack of scientific/research literacy in the lay population; 4) Lack of community engagement including Primary Care Physicians; 5) Lack of cost data to adequately budget for inclusion efforts. Best practices included health literate consent forms, cultural competency, and motivational interview training for coordinators. Conclusion: NIMICT’s mixed methods approach contributes new perspectives on unique challenges in stroke clinical research. These findings will inform strategies to improve minority recruitment and retention among neurological clinical trials.

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